Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness

Development and Survival of MYC-driven Lymphomas Requires MYC-Antagonist MNT to Curb MYC-induced Apoptosis

(2020) Hai Vu Nguyen et al.   BLOOD

Target gene-independent functions of MYC oncoproteins

(2020) Apoorva Baluapuri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

(2020) Arnaud Augert et al.   CANCER CELL

Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma

(2020) Nathiya Muthalagu et al.   Cancer Discovery

The Roles of Embryonic Transcription Factor BRACHYURY in Tumorigenesis and Progression

(2020) Ming Chen et al.   Frontiers in Oncology

The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer

(2020) Masaru Sasaki et al.   CANCER LETTERS

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities

(2019) Andrea Scelfo et al.   MOLECULAR CELL

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

(2019) Nadezda A. Fursova et al.   MOLECULAR CELL

Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15

(2019) Yuna Guo et al.   AGING CELL

Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis

(2019) Haritha Mathsyaraja et al.   GENES & DEVELOPMENT

Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma

(2019) Paula Llabata et al.   MOLECULAR CANCER RESEARCH

Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization

(2018) Curtis A. Thorne et al.   DEVELOPMENTAL CELL

MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6

(2018) Bastian Stielow et al.   PLoS Genetics

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

(2018) Franz X. Schaub et al.   Cell Systems

Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia

(2018) Shih-Han Lee et al.   NATURE

The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis

(2018) Patrick A. Carroll et al.   Frontiers of Medicine

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

(2018) Derek H. Janssens et al.   Epigenetics & Chromatin

Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer

(2017) Sagar R. Shah et al.   Cell Reports

Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes

(2017) Mitsuhiro Endoh et al.   eLife

MNT and Emerging Concepts of MNT‐MYC Antagonism

(2017) Guang Yang et al.   Genes

Lung Cancer Subtypes Generate Unique Immune Responses

(2016) Stephanie E. Busch et al.   JOURNAL OF IMMUNOLOGY

Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD)

(2016) Q-Y Sun et al.   LEUKEMIA

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells

(2016) Ayumu Suzuki et al.   Nature Communications

Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer

(2016) H. Zhang et al.   Cancer Discovery

Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

(2016) Anne Laugesen et al.   Cold Spring Harbor Perspectives in Medicine

Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis

(2015) Patrick A. Carroll et al.   CANCER CELL

Redeployment of Myc and E2f1–3 drives Rb-deficient cell cycles

(2015) Huayang Liu et al.   NATURE CELL BIOLOGY

Context-dependent actions of Polycomb repressors in cancer

(2015) M Koppens et al.   ONCOGENE

MYC, Metabolism, and Cancer

(2015) Z. E. Stine et al.   Cancer Discovery

A simple method for generating high-resolution maps of genome-wide protein binding

(2015) Peter J Skene et al.   eLife

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

(2014) Li Shen et al.   BMC GENOMICS

Mga is essential for the survival of pluripotent cells during peri-implantation development

(2014) A. J. Washkowitz et al.   DEVELOPMENT

Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

(2014) Rui Du et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

(2014) Francisco J. Sánchez-Rivera et al.   NATURE

Processed pseudogenes acquired somatically during cancer development

(2014) Susanna L. Cooke et al.   Nature Communications

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Max is a repressor of germ cell-related gene expression in mouse embryonic stem cells

(2013) Ikuma Maeda et al.   Nature Communications

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

(2012) Javier Muñoz et al.   EMBO JOURNAL

MGA, a suppressor ofMYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

(2012) Lorenzo De Paoli et al.   LEUKEMIA & LYMPHOMA

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis

(2012) J. M. Link et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms

(2011) Tomoaki Hishida et al.   Cell Stem Cell

L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure

(2011) Patrick Trojer et al.   MOLECULAR CELL

The tbx/bHLH transcription factor mga regulates gata4 and organogenesis

(2010) Amir Rikin et al.   DEVELOPMENTAL DYNAMICS

The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

(2010) Romaine I. Fernando et al.   JOURNAL OF CLINICAL INVESTIGATION

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

(2009) Laurens G. van der Flier et al.   CELL

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression

(2008) M T Pickering et al.   ONCOGENE