Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

Diversity and robustness of bone morphogenetic protein pattern formation

(2021) Aasakiran Madamanchi et al.   DEVELOPMENT

Cytonemes with complex geometries and composition extend into invaginations of target cells

(2021) Brent M. Wood et al.   JOURNAL OF CELL BIOLOGY

Generation of extracellular morphogen gradients: the case for diffusion

(2021) Kristina S. Stapornwongkul et al.   NATURE REVIEWS GENETICS

Polarized sorting of Patched enables cytoneme‐mediated Hedgehog reception in the Drosophila wing disc

(2020) Laura González‐Méndez et al.   EMBO JOURNAL

Specialized cytonemes induce self-organization of stem cells

(2020) Sergi Junyent et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

(2020) Ian J. McGough et al.   NATURE

Analysis on gene modular network reveals morphogen-directed development robustness in Drosophila

(2020) Shuo Zhang et al.   Cell Discovery

Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal

(2020) Yusuke Mii et al.   Frontiers in Cell and Developmental Biology

Hedgehog produced by the drosophila wing imaginal disc induces distinct responses in three target tissues

(2020) Ryo Hatori et al.   DEVELOPMENT

Glutamate signaling at cytoneme synapses

(2019) Hai Huang et al.   SCIENCE

Cytoneme-mediated signaling essential for tumorigenesis

(2019) Sol Fereres et al.   PLoS Genetics

Morphogen gradient reconstitution reveals Hedgehog pathway design principles

(2018) Pulin Li et al.   SCIENCE

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

(2018) Benjamin Mattes et al.   eLife

The Elegance of Sonic Hedgehog: Emerging Novel Functions for a Classic Morphogen

(2018) A. Denise R. Garcia et al.   JOURNAL OF NEUROSCIENCE

Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

(2018) Lijuan Du et al.   eLife

Adult Muscle Formation RequiresDrosophilaMoleskin for Proliferation of Wing Disc-Associated Muscle Precursors

(2017) Kumar Vishal et al.   GENETICS

Cytoneme-mediated cell-cell contacts for Hedgehog reception

(2017) Laura González-Méndez et al.   eLife

Adult Muscle Formation RequiresDrosophilaMoleskin for Proliferation of Wing Disc-Associated Muscle Precursors

(2017) Kumar Vishal et al.   GENETICS

Role of cytonemes in Wnt transport

(2016) Eliana Stanganello et al.   JOURNAL OF CELL SCIENCE

Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs

(2016) Yasuo Yamazaki et al.   NATURE CELL BIOLOGY

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

(2016) Masato Morikawa et al.   Cold Spring Harbor Perspectives in Biology

Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes

(2016) Hai Huang et al.   eLife

Decapentaplegic and growth control in the developing Drosophila wing

(2015) Takuya Akiyama et al.   NATURE

Filopodia-based Wnt transport during vertebrate tissue patterning

(2015) Eliana Stanganello et al.   Nature Communications

Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

(2015) Hai Huang et al.   eLife

Paracrine signaling mediated at cell-cell contacts

(2014) Sougata Roy et al.   BIOESSAYS

Cytoneme-Mediated Contact-Dependent Transport of the Drosophila Decapentaplegic Signaling Protein

(2014) S. Roy et al.   SCIENCE

Hedgehog on the move: a precise spatial control of Hedgehog dispersion shapes the gradient

(2013) Ana-Citlali Gradilla et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

(2013) Marcus Bischoff et al.   NATURE CELL BIOLOGY

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Homeobox Transcription Factor Cut Coordinates Patterning and Growth During Drosophila Airway Remodeling

(2013) C. Pitsouli et al.   Science Signaling

Morphogen Gradients: From Generation to Interpretation

(2011) Katherine W. Rogers et al.   Annual Review of Cell and Developmental Biology

SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless

(2011) Peng Zhang et al.   CELL RESEARCH

Regulation of BMP activity and range in Drosophila wing development

(2011) Laurel A Raftery et al.   CURRENT OPINION IN CELL BIOLOGY

Drosophila G-protein-coupled receptor kinase 2 regulates cAMP-dependent Hedgehog signaling

(2011) S. Cheng et al.   DEVELOPMENT

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking

(2011) Matthias Nowak et al.   NATURE CELL BIOLOGY

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium

(2011) A. Callejo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity of Drosophila Cytonemes for Distinct Signaling Pathways

(2011) S. Roy et al.   SCIENCE

Vesicular and Plasma Membrane Transporters for Neurotransmitters

(2011) R. D. Blakely et al.   Cold Spring Harbor Perspectives in Biology

Role of the Drosophila Non-Visual ß-Arrestin Kurtz in Hedgehog Signalling

(2011) Cristina Molnar et al.   PLoS Genetics

Morphogen gradients in development: from form to function

(2011) Jan L. Christian   Wiley Interdisciplinary Reviews-Developmental Biology

Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells

(2010) Nichol E. Holodick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc

(2009) A. Perez-Garijo et al.   DEVELOPMENT

The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene

(2008) D. J. McKay et al.   DEVELOPMENT