Morphogen gradient reconstitution reveals Hedgehog pathway design principles

Scaling Pattern to Variations in Size during Development of the Vertebrate Neural Tube

(2016) Aysu Uygur et al.   DEVELOPMENTAL CELL

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update

(2016) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Dynamics of epigenetic regulation at the single-cell level

(2016) L. Bintu et al.   SCIENCE

Morphogen rules: design principles of gradient-mediated embryo patterning

(2015) J. Briscoe et al.   DEVELOPMENT

Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms

(2015) Michael Cohen et al.   Nature Communications

A Predictive Model of Bifunctional Transcription Factor Signaling during Embryonic Tissue Patterning

(2014) Jan Philipp Junker et al.   DEVELOPMENTAL CELL

Positional Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical Framework

(2014) G. Tka ik et al.   GENETICS

An inducible transgene expression system for zebrafish and chick

(2013) S. S. Gerety et al.   DEVELOPMENT

The Utility of Paradoxical Components in Biological Circuits

(2013) Yuval Hart et al.   MOLECULAR CELL

Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning

(2013) Timothy A. Sanders et al.   NATURE

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

(2013) Marcus Bischoff et al.   NATURE CELL BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

(2012) Nikolaos Balaskas et al.   CELL

Differential Diffusivity of Nodal and Lefty Underlies a Reaction-Diffusion Patterning System

(2012) P. Muller et al.   SCIENCE

Signaling Mechanisms Controlling Cell Fate and Embryonic Patterning

(2012) N. Perrimon et al.   Cold Spring Harbor Perspectives in Biology

Pulsed Feedback Defers Cellular Differentiation

(2012) Joe H. Levine et al.   PLOS BIOLOGY

Morphogen Gradients: From Generation to Interpretation

(2011) Katherine W. Rogers et al.   Annual Review of Cell and Developmental Biology

Improved Tet-responsive promoters with minimized background expression

(2010) Rainer Loew et al.   BMC BIOTECHNOLOGY

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

(2010) E. W. Humke et al.   GENES & DEVELOPMENT

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Morphogen Gradient Formation

(2009) O. Wartlick et al.   Cold Spring Harbor Perspectives in Biology

Positive feedback in cellular control systems

(2008) Alexander Y. Mitrophanov et al.   BIOESSAYS