Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system

Structural analysis of the outer surface proteins from Borrelia burgdorferi paralogous gene family 54 that are thought to be the key players in the pathogenesis of Lyme disease

(2020) Kalvis Brangulis et al.   JOURNAL OF STRUCTURAL BIOLOGY

Skin Interface, a Key Player for Borrelia Multiplication and Persistence in Lyme Borreliosis

(2020) Quentin Bernard et al.   TRENDS IN PARASITOLOGY

New Insights Into CRASP-Mediated Complement Evasion in the Lyme Disease Enzootic Cycle

(2020) Yi-Pin Lin et al.   Frontiers in Cellular and Infection Microbiology

Complement Evasion by Lyme Disease Spirochetes

(2020) Jon T. Skare et al.   TRENDS IN MICROBIOLOGY

Complement Evasion Contributes to Lyme Borreliae–Host Associations

(2020) Yi-Pin Lin et al.   TRENDS IN PARASITOLOGY

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C

(2020) Yi-Pin Lin et al.   PLoS Pathogens

Complement evasion strategies of Borrelia burgdorferi sensu lato

(2020) Vinaya Dulipati et al.   FEBS LETTERS

Interactions between Borrelia burgdorferi and ticks

(2020) Cheyne Kurokawa et al.   NATURE REVIEWS MICROBIOLOGY

Identification of the proteins of Borrelia garinii interacting with human brain microvascular endothelial cells

(2020) Zuzana Tkáčová et al.   Ticks and Tick-Borne Diseases

Outer surface protein polymorphisms linked to host-spirochete association in Lyme borreliae

(2019) Danielle M. Tufts et al.   MOLECULAR MICROBIOLOGY

Tracking of Borrelia afzelii transmission from infected Ixodes ricinus nymphs to mice

(2019) Tereza Pospisilova et al.   INFECTION AND IMMUNITY

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Susceptibility to infection with Borrelia afzelii and TLR2 polymorphism in a wild reservoir host

(2019) Andrea Gomez-Chamorro et al.   Scientific Reports

Getting under the birds’ skin: tissue tropism of Borrelia burgdorferi s.l. in naturally and experimentally infected avian hosts

(2019) Ana Cláudia Norte et al.   MICROBIAL ECOLOGY

The hijackers guide to escaping complement: Lessons learned from pathogens

(2019) David Ermert et al.   MOLECULAR IMMUNOLOGY

A soft tick Ornithodoros moubata salivary protein OmCI is a potent inhibitor to prevent avian complement activation

(2019) Amber M. Frye et al.   Ticks and Tick-Borne Diseases

Vector competence studies with hard ticks and Borrelia burgdorferi sensu lato spirochetes: A review

(2019) Lars Eisen   Ticks and Tick-Borne Diseases

Host and parasite thermal ecology jointly determine the effect of climate warming on epidemic dynamics

(2018) Alyssa-Lois M. Gehman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental infection by microparasites affects the oxidative balance in their avian reservoir host the blackbird Turdus merula

(2018) Ana Cláudia Norte et al.   Ticks and Tick-Borne Diseases

Identification of Lyme borreliae proteins promoting vertebrate host blood-specific spirochete survival in Ixodes scapularis nymphs using artificial feeding chambers

(2018) Thomas Hart et al.   Ticks and Tick-Borne Diseases

Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission

(2018) Thomas Hart et al.   PLoS Pathogens

Anticoagulants impact on innate immune responses and bacterial survival in whole blood models of Neisseria meningitidis infection

(2018) Lea Strobel et al.   Scientific Reports

Infection Kinetics and Tropism of Borrelia burgdorferi sensu lato in Mouse After Natural (via Ticks) or Artificial (Needle) Infection Depends on the Bacterial Strain

(2018) Natacha Sertour et al.   Frontiers in Microbiology

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts

(2018) Ashley L. Marcinkiewicz et al.   CELLULAR MICROBIOLOGY

The role of complement inhibitors beyond controlling inflammation

(2017) A. M. Blom   JOURNAL OF INTERNAL MEDICINE

Interactions between host immune response and antigenic variation that control Borrelia burgdorferi population dynamics

(2017) Wei Zhou et al.   MICROBIOLOGY-SGM

UFBoot2: Improving the Ultrafast Bootstrap Approximation

(2017) Diep Thi Hoang et al.   MOLECULAR BIOLOGY AND EVOLUTION

ModelFinder: fast model selection for accurate phylogenetic estimates

(2017) Subha Kalyaanamoorthy et al.   NATURE METHODS

Closely-related Borrelia burgdorferi (sensu stricto) strains exhibit similar fitness in single infections and asymmetric competition in multiple infections

(2017) Evelyn C. Rynkiewicz et al.   Parasites & Vectors

Genomic insights into the ancient spread of Lyme disease across North America

(2017) Katharine S. Walter et al.   Nature Ecology & Evolution

Inefficient co-feeding transmission of Borrelia afzelii in two common European songbirds

(2017) Dieter J. A. Heylen et al.   Scientific Reports

Recurrent evolution of host and vector association in bacteria of the Borrelia burgdorferi sensu lato species complex

(2016) Noémie S. Becker et al.   BMC GENOMICS

Co-infections and transmission dynamics in a tick-borne bacterium community exposed to songbirds

(2016) Dieter Heylen et al.   ENVIRONMENTAL MICROBIOLOGY

Complement in disease: a defence system turning offensive

(2016) Daniel Ricklin et al.   Nature Reviews Nephrology

Live-vaccinia virus encapsulation in pH-sensitive polymer increases safety of a reservoir-targeted Lyme disease vaccine by targeting gastrointestinal release

(2016) Aurelie Kern et al.   VACCINE

Can environmental change affect host/parasite-mediated speciation?

(2016) Franziska S. Brunner et al.   ZOOLOGY

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

(2016) Brandon L. Garcia et al.   PLoS Pathogens

Lyme borreliosis

(2016) Allen C. Steere et al.   Nature Reviews Disease Primers

Evidence for Host-Genotype Associations of Borrelia burgdorferi Sensu Stricto

(2016) Samir Mechai et al.   PLoS One

Genetic Dissection of the Host Tropism of Human-Tropic Pathogens

(2015) Florian Douam et al.   Annual Review of Genetics

Evolutionary Aspects of Emerging Lyme Disease in Canada

(2015) N. H. Ogden et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

BGA66 and BGA71 facilitate complement resistance ofBorrelia bavariensisby inhibiting assembly of the membrane attack complex

(2015) Claudia Hammerschmidt et al.   MOLECULAR MICROBIOLOGY

Virulence of recurrent infestations with Borrelia-infected ticks in a Borrelia-amplifying bird

(2015) Dieter J. A. Heylen et al.   Scientific Reports

Evolutionary genomics of Borrelia burgdorferi sensu lato: Findings, hypotheses, and the rise of hybrids

(2014) Wei-Gang Qiu et al.   INFECTION GENETICS AND EVOLUTION

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

(2014) Lam-Tung Nguyen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Assessing the Effects of Climate on Host-Parasite Interactions: A Comparative Study of European Birds and Their Parasites

(2014) Anders Pape Møller et al.   PLoS One

Strain-Specific Variation of the Decorin-Binding Adhesin DbpA Influences the Tissue Tropism of the Lyme Disease Spirochete

(2014) Yi-Pin Lin et al.   PLoS Pathogens

Versatile Roles of CspA Orthologs in Complement Inactivation of Serum-Resistant Lyme Disease Spirochetes

(2013) Claudia Hammerschmidt et al.   INFECTION AND IMMUNITY

Ecological factors that determine Ixodes ricinus tick burdens in the great tit (Parus major), an avian reservoir of Borrelia burgdorferi s.l.

(2013) Dieter Heylen et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

BBA70 ofBorrelia burgdorferiIs a Novel Plasminogen-binding Protein

(2013) Arno Koenigs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Experimental infection of cotton rats and bobwhite quail with Rickettsia parkeri

(2013) Gail Moraru et al.   Parasites & Vectors

CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway

(2013) T. Hallstrom et al.   mBio

Changing geographic ranges of ticks and tick-borne pathogens: drivers, mechanisms and consequences for pathogen diversity

(2013) Nick H. Ogden et al.   Frontiers in Cellular and Infection Microbiology

Genetics ofBorrelia burgdorferi

(2012) Dustin Brisson et al.   Annual Review of Genetics

Spatial spread and demographic expansion of Lyme borreliosis spirochaetes in Eurasia

(2012) Stephanie A. Vollmer et al.   INFECTION GENETICS AND EVOLUTION

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

(2012) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

(2012) Tao Lin et al.   PLoS One

Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression

(2012) Peter Kraiczy et al.   Ticks and Tick-Borne Diseases

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

(2011) Tim J. Schuijt et al.   Cell Host & Microbe

Allelic Variation of the Lyme Disease Spirochete Adhesin DbpA Influences Spirochetal Binding to Decorin, Dermatan Sulfate, and Mammalian Cells

(2011) Vivian M. Benoit et al.   INFECTION AND IMMUNITY

Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi

(2011) Ignas Bunikis et al.   JOURNAL OF MICROBIOLOGICAL METHODS

A molecular evolutionary concept connecting nonhost resistance, pathogen host range, and pathogen speciation

(2011) Paul Schulze-Lefert et al.   TRENDS IN PLANT SCIENCE

TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations

(2010) Federico Abascal et al.   NUCLEIC ACIDS RESEARCH

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice

(2010) N.D. van Burgel et al.   Ticks and Tick-Borne Diseases

Fast, adaptive evolution at a bacterial host-resistance locus: The PFam54 gene array in Borrelia burgdorferi

(2009) Ewa Wywial et al.   GENE

Fibronectin Binds to and Induces Conformational Change in a Disordered Region of Leptospiral Immunoglobulin-like Protein B

(2009) Yi-Pin Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial Dynamics of Lyme Disease: A Review

(2008) Mary E. Killilea et al.   EcoHealth

The Tick Salivary Protein Salp15 Inhibits the Killing of Serum-Sensitive Borrelia burgdorferi Sensu Lato Isolates

(2008) T. J. Schuijt et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi Complement Regulator-Acquiring Surface Protein 2 Does Not Contribute to Complement Resistance or Host Infectivity

(2008) Adam S. Coleman et al.   PLoS One

Factor H family proteins and human diseases

(2008) Mihály Józsi et al.   TRENDS IN IMMUNOLOGY

Convergence and parallelism reconsidered: what have we learned about the genetics of adaptation?

(2007) J ARENDT et al.   TRENDS IN ECOLOGY & EVOLUTION