Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis

Intranasal vaccination with Listeria ivanovii as vector of Mycobacterium tuberculosis antigens promotes specific lung-localized cellular and humoral immune responses

(2020) Ming-juan Jiang et al.   Scientific Reports

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

(2020) João Calmeiro et al.   Pharmaceutics

An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes

(2020) Md Anik Ashfaq Khan et al.   Parasites & Vectors

Investigation of the antigenicity and protective efficacy of Leishmania promastigote membrane antigens in search of potential diagnostic and vaccine candidates against visceral leishmaniasis

(2020) Sarfaraz Ahmad Ejazi et al.   Parasites & Vectors

A TLR9-adjuvanted vaccine formulated into dissolvable microneedle patches or cationic liposomes protects against leishmaniasis after skin or subcutaneous immunization

(2020) Juliane S. Lanza et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The macrophage microtubule network acts as a key cellular controller of the intracellular fate of Leishmania infantum

(2020) Sandrine Cojean et al.   PLoS Neglected Tropical Diseases

Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses

(2020) Youhui Si et al.   Science Advances

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

(2020) Ahmed O. Hassan et al.   CELL

Effective Nanoparticle-Based Nasal Vaccine Against Latent and Congenital Toxoplasmosis in Sheep

(2020) Céline Ducournau et al.   Frontiers in Immunology

The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy

(2019) Juliana Elena Silveira Pratti et al.   PLoS Neglected Tropical Diseases

Pam3CSK4 adjuvant given intranasally boosts anti-Leishmania immunogenicity but not protective immune responses conferred by LaAg vaccine against visceral leishmaniasis

(2019) Caio Loureiro Salgado et al.   MICROBES AND INFECTION

Nanoencapsulated retinoic acid as a safe tolerogenic adjuvant for intranasal vaccination against cutaneous leishmaniasis

(2019) Izabella P.S. Bezerra et al.   VACCINE

The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro

(2019) Laíse B. Oliveira et al.   Frontiers in Cellular and Infection Microbiology

Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy

(2019) Alti Dayakar et al.   Frontiers in Immunology

Functional aspects of T cell diversity in visceral leishmaniasis

(2019) Junaid Jibran Jawed et al.   BIOMEDICINE & PHARMACOTHERAPY

Nrf2 downregulates zymosan-induced neutrophil activation and modulates migration

(2019) Doumet Georges Helou et al.   PLoS One

Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge

(2019) Xiaoyan Zheng et al.   PLoS Pathogens

PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani

(2018) Samar Habib et al.   INFECTION AND IMMUNITY

Intranasal but not subcutaneous vaccination with LaAg allows rapid expansion of protective immunity against cutaneous leishmaniasis

(2018) Izabella Pereira Silva Bezerra et al.   VACCINE

Noninvasive vaccination against infectious diseases

(2018) Zhichao Zheng et al.   Human Vaccines & Immunotherapeutics

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

Leishmania donovani Exploits Macrophage Heme Oxygenase-1 To Neutralize Oxidative Burst and TLR Signaling–Dependent Host Defense

(2018) Shriya Saha et al.   JOURNAL OF IMMUNOLOGY

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

(2018) Silvia Sánchez-Ramón et al.   Frontiers in Immunology

Nanoparticle Vaccines Against Infectious Diseases

(2018) Rashmirekha Pati et al.   Frontiers in Immunology

Synthetic parasites: a successful mucosal nanoparticle vaccine against Toxoplasma congenital infection in mice

(2017) Céline Ducournau et al.   Future Microbiology

Microbiota: Leishmaniasis breaks the equilibrium

(2017) Irene Vacca   NATURE REVIEWS MICROBIOLOGY

Intranasal co-administration of 1,8-cineole with influenza vaccine provide cross-protection against influenza virus infection

(2017) Yun Li et al.   PHYTOMEDICINE

Splenic CD4+ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression

(2017) Audrie A. Medina-Colorado et al.   PLoS One

Role of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines

(2016) Antara Banerjee et al.   CELLULAR IMMUNOLOGY

Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

(2016) Mariana Costa Duarte et al.   Revista da Sociedade Brasileira de Medicina Tropical

Dendritic Cells andLeishmaniaInfection: Adding Layers of Complexity to a Complex Disease

(2016) Daniel Feijó et al.   Journal of Immunology Research

Porous nanoparticles as delivery system of complex antigens for an effective vaccine against acute and chronic Toxoplasma gondii infection

(2015) Isabelle Dimier-Poisson et al.   BIOMATERIALS

Therapy with radio-attenuated vaccine in experimental murine visceral leishmaniasis showed enhanced T cell and inducible nitric oxide synthase levels, suppressed tumor growth factor-beta production with higher expression of some signaling molecules

(2015) Sanchita Datta et al.   Brazilian Journal of Infectious Diseases

Vaccines for visceral leishmaniasis: A review

(2015) Keerti Jain et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Intranasal vaccination with killed Leishmania amazonensis promastigotes antigen (LaAg) associated with CAF01 adjuvant induces partial protection in BALB/c mice challenged with Leishmania (infantum) chagasi - CORRIGENDUM

(2015) JANINE MIRANDA LEAL et al.   PARASITOLOGY

Intranasal Vaccination with Leishmanial Antigens Protects Golden Hamsters (Mesocricetus auratus) Against Leishmania (Viannia) braziliensis Infection

(2015) Luzinei da Silva-Couto et al.   PLoS Neglected Tropical Diseases

Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies

(2015) Shujing Wang et al.   Protein & Cell

Choose your models wisely: How different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro

(2014) Heleen Dewitte et al.   JOURNAL OF CONTROLLED RELEASE

Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection

(2014) Herbert de Matos Guedes et al.   Parasites & Vectors

Immune Regulation during Chronic Visceral Leishmaniasis

(2014) Rebecca J. Faleiro et al.   PLoS Neglected Tropical Diseases

Leishmania donovaniPrevents Oxidative Burst-mediated Apoptosis of Host Macrophages through Selective Induction of Suppressors of Cytokine Signaling (SOCS) Proteins

(2013) Supriya Srivastav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T Cell-Derived IL-10 Determines Leishmaniasis Disease Outcome and Is Suppressed by a Dendritic Cell Based Vaccine

(2013) Tobias Schwarz et al.   PLoS Pathogens

MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length

(2012) J. K. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cell-based in vitro assays for vaccine immunogenicity

(2012) Rob J. Vandebriel et al.   Human Vaccines & Immunotherapeutics

Low and high-dose intradermal infection with Leishmania majorand Leishmania amazonensis in C57BL/6 mice

(2010) Denise Fonseca Côrtes et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Positively-Charged, Porous, Polysaccharide Nanoparticles Loaded with Anionic Molecules Behave as ‘Stealth’ Cationic Nanocarriers

(2009) Archibald Paillard et al.   PHARMACEUTICAL RESEARCH