Immune Regulation during Chronic Visceral Leishmaniasis

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Risk Factors for Visceral Leishmaniasis and Asymptomatic Leishmania donovani Infection in India and Nepal

(2014) Albert Picado et al.   PLoS One

The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum

(2013) Lise Lefèvre et al.   IMMUNITY

A New Model of Progressive Visceral Leishmaniasis in Hamsters by Natural Transmission via Bites of Vector Sand Flies

(2013) Hamide Aslan et al.   JOURNAL OF INFECTIOUS DISEASES

CD8 T Cell Exhaustion in Human Visceral Leishmaniasis

(2013) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

Common variants in the HLA-DRB1–HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

(2013) Michaela Fakiola et al.   NATURE GENETICS

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

Reassessment of Immune Correlates in Human Visceral Leishmaniasis as Defined by Cytokine Release in Whole Blood

(2012) Om Prakash Singh et al.   Clinical and Vaccine Immunology

Leishmaniasis: an update of current pharmacotherapy

(2012) Shyam Sundar et al.   EXPERT OPINION ON PHARMACOTHERAPY

Tissue damage and immunity in cutaneous leishmaniasis

(2012) S. Nylén et al.   PARASITE IMMUNOLOGY

Regulatory T Cells Suppress T Cell Activation at the Pathologic Site of Human Visceral Leishmaniasis

(2012) Ambak K. Rai et al.   PLoS One

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

The diverse roles of monocytes in inflammation caused by protozoan parasitic diseases

(2012) Meru Sheel et al.   TRENDS IN PARASITOLOGY

Leishmanization revisited: Immunization with a naturally attenuated cutaneous Leishmania donovani isolate from Sri Lanka protects against visceral leishmaniasis

(2012) Laura-Isobel McCall et al.   VACCINE

Visceral leishmaniasis in a patient with AIDS: early pathological diagnosis using conventional histology, PCR and electron microscopy is the key for adequate treatment

(2012) Albrecht Stenzinger et al.   VIRCHOWS ARCHIV

Evidence for Involvement of Th17 Type Responses in Post Kala Azar Dermal Leishmaniasis (PKDL)

(2012) Gajendra Kumar Katara et al.   PLoS Neglected Tropical Diseases

Leishmania Induces Survival, Proliferation and Elevated Cellular dNTP Levels in Human Monocytes Promoting Acceleration of HIV Co-Infection

(2012) David J. Mock et al.   PLoS Pathogens

Leishmania promastigotes: building a safe niche within macrophages

(2012) Neda Moradin et al.   Frontiers in Cellular and Infection Microbiology

Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India

(2011) Sanjana Mehrotra et al.   BMC Medical Genetics

No evidence for association between SLC11A1and visceral leishmaniasis in India

(2011) Sanjana Mehrotra et al.   BMC Medical Genetics

Leishmaniasis

(2011) Lukasz Kedzierski   Human vaccines & immunotherapeutics

Post-kala-azar dermal leishmaniasis: recent developments

(2011) Sarman Singh et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

IL-27 and IL-21 Are Associated with T Cell IL-10 Responses in Human Visceral Leishmaniasis

(2011) Nasim Akhtar Ansari et al.   JOURNAL OF IMMUNOLOGY

IL-10 Neutralization Promotes Parasite Clearance in Splenic Aspirate Cells From Patients With Visceral Leishmaniasis

(2011) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial

(2011) Shyam Sundar et al.   LANCET

Diagnosis of Indian Visceral Leishmaniasis by Nucleic Acid Detection Using PCR

(2011) Pankaj Srivastava et al.   PLoS One

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis

(2011) Jaya Chakravarty et al.   VACCINE

Post-Kala-azar Dermal Leishmaniasis in Nepal: A Retrospective Cohort Study (2000–2010)

(2011) Surendra Uranw et al.   PLoS Neglected Tropical Diseases

Foxp3 and IL-10 Expression Correlates with Parasite Burden in Lesional Tissues of Post Kala Azar Dermal Leishmaniasis (PKDL) Patients

(2011) Gajendra Kumar Katara et al.   PLoS Neglected Tropical Diseases

Incidence of Symptomatic and Asymptomatic Leishmania donovani Infections in High-Endemic Foci in India and Nepal: A Prospective Study

(2011) Bart Ostyn et al.   PLoS Neglected Tropical Diseases

Serological Markers of Sand Fly Exposure to Evaluate Insecticidal Nets against Visceral Leishmaniasis in India and Nepal: A Cluster-Randomized Trial

(2011) Kamlesh Gidwani et al.   PLoS Neglected Tropical Diseases

Evaluation of Ex Vivo Human Immune Response against Candidate Antigens for a Visceral Leishmaniasis Vaccine

(2010) Rajiv Kumar et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Hematologic Changes in Visceral Leishmaniasis/Kala Azar

(2010) Neelam Varma et al.   INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION

Post-kala-azar dermal leishmaniasis - an overview

(2010) Sudipto Ganguly et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice

(2010) Jane E. Dalton et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10

(2010) M. Rodriguez-Garcia et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Risk factors for visceral leishmaniasis in India: further evidence on the role of domestic animals

(2010) S. P. Singh et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

(2010) Alejandro Llanos-Cuentas et al.   VACCINE

Of Cattle, Sand Flies and Men: A Systematic Review of Risk Factor Analyses for South Asian Visceral Leishmaniasis and Implications for Elimination

(2010) Caryn Bern et al.   PLoS Neglected Tropical Diseases

Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63

(2010) Irazú Contreras et al.   PLoS Pathogens

IL-27 Regulates IL-10 and IL-17 from CD4+ Cells in Nonhealing Leishmania major Infection

(2009) C. F. Anderson et al.   JOURNAL OF IMMUNOLOGY

IL-21 Mediates Suppressive Effects via Its Induction of IL-10

(2009) R. Spolski et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis

(2009) Iván D. Vélez et al.   VACCINE

B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

(2009) Trupti Joshi et al.   PLoS Pathogens

The Relationship between Leishmaniasis and AIDS: the Second 10 Years

(2008) J. Alvar et al.   CLINICAL MICROBIOLOGY REVIEWS

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections

(2008) Sang-Jun Ha et al.   IMMUNOLOGICAL REVIEWS

Increased Levels of Interleukin‐10 and IgG3 Are Hallmarks of Indian Post–Kala-Azar Dermal Leishmaniasis

(2008) Sudipto Ganguly et al.   JOURNAL OF INFECTIOUS DISEASES

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE

Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif

(2008) Issa Abu-Dayyeh et al.   PLoS Neglected Tropical Diseases