Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts

(2015) Jurian Schuijers et al.   Cell Stem Cell

Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine

(2015) Samuel Asfaha et al.   Cell Stem Cell

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling

(2015) Jitka Stancikova et al.   CELLULAR SIGNALLING

β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis

(2015) Jing Cai et al.   GENES & DEVELOPMENT

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice

(2014) L. Tumova et al.   MOLECULAR CANCER THERAPEUTICS

Wnt signaling in adult intestinal stem cells and cancer

(2013) Michaela Krausova et al.   CELLULAR SIGNALLING

Intestinal label-retaining cells are secretory precursors expressing Lgr5

(2013) Simon J. A. Buczacki et al.   NATURE

A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice

(2012) J. Waaler et al.   CANCER RESEARCH

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

(2012) Anne E. Powell et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Troy, a Tumor Necrosis Factor Receptor Family Member, Interacts With Lgr5 to Inhibit Wnt Signaling in Intestinal Stem Cells

(2012) Bohumil Fafilek et al.   GASTROENTEROLOGY

A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal

(2012) J. H. van Es et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

(2012) Johan H. van Es et al.   NATURE CELL BIOLOGY

Paneth Cells in Intestinal Homeostasis and Tissue Injury

(2012) Sabrina Roth et al.   PLoS One

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling

(2011) Lenka Doubravska et al.   CELLULAR SIGNALLING

Generation of two modified mouse alleles of the Hic1 tumor suppressor gene

(2011) Vendula Pospichalova et al.   GENESIS

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis

(2011) M. L. Angus-Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

(2009) Laurens G. van der Flier et al.   CELL

Dazap2 modulates transcription driven by the Wnt effector TCF-4

(2009) Jan Lukas et al.   NUCLEIC ACIDS RESEARCH

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE