The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells
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Title
The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-24
DOI
10.1038/s41598-021-89931-9
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Note: Only part of the references are listed.- Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update
- (2020) Jinyun Dong et al. DRUG RESISTANCE UPDATES
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- (2020) Dong Jun Park et al. Journal for ImmunoTherapy of Cancer
- A Novel Function for KLF4 in Modulating the De-Differentiation of EpCAM−/CD133− nonStem Cells into EpCAM+/CD133+ Liver Cancer Stem Cells in HCC Cell Line HuH7
- (2020) Zeynep Firtina Karagonlar et al. Cells
- A Novel CD133- and EpCAM-Targeted Liposome With Redox-Responsive Properties Capable of Synergistically Eliminating Liver Cancer Stem Cells
- (2020) Zihua Wang et al. Frontiers in Chemistry
- Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications
- (2019) Yu Toyoda et al. Frontiers in Pharmacology
- Hepatocellular Carcinoma
- (2019) Augusto Villanueva NEW ENGLAND JOURNAL OF MEDICINE
- Functional consequences of enhanced expression of STIM1 and Orai1 in Huh-7 hepatocellular carcinoma tumor-initiating cells
- (2019) B. Karacicek et al. BMC CANCER
- Antiproliferative activity of (R)-4′-methylklavuzon on hepatocellular carcinoma cells and EpCAM+/CD133+ cancer stem cells via SIRT1 and Exportin-1 (CRM1) inhibition
- (2019) Murat Delman et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The ABC subfamily A transporters: Multifaceted players with incipient potentialities in cancer
- (2019) Michela Pasello et al. SEMINARS IN CANCER BIOLOGY
- miR-223 overexpression inhibits doxorubicin-induced autophagy by targeting FOXO3a and reverses chemoresistance in hepatocellular carcinoma cells
- (2019) Yue Zhou et al. Cell Death & Disease
- Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway
- (2018) Regina Cheuk-Lam Lo et al. CELL DEATH AND DIFFERENTIATION
- ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma
- (2018) Maria Paula Ceballos Mancini et al. CURRENT MEDICINAL CHEMISTRY
- HBV infection potentiates resistance to S-phase arrest-inducing chemotherapeutics by inhibiting CHK2 pathway in diffuse large B-cell lymphoma
- (2018) Xinying Zhao et al. Cell Death & Disease
- Relevance of Two Genes in the Multidrug Resistance of Hepatocellular Carcinoma: In Vivo and Clinical Studies
- (2018) Zhengang Sun et al. TUMORI
- Targeting Cancer Stemness in the Clinic: From Hype to Hope
- (2018) Caner Saygin et al. Cell Stem Cell
- The evolving concept of liver cancer stem cells
- (2017) Kouki Nio et al. Molecular Cancer
- Lessons Learned from Two Decades of Anticancer Drugs
- (2017) Zhichao Liu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Hepatitis B virus X protein promotes the stem-like properties of OV6+ cancer cells in hepatocellular carcinoma
- (2017) Chao Wang et al. Cell Death & Disease
- Effect of adipocyte-secreted factors on EpCAM+/CD133+ hepatic stem cell population
- (2016) Zeynep Firtina Karagonlar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Epithelial cell adhesion molecule in human hepatocellular carcinoma cell lines: a target of chemoresistence
- (2016) Yan Li et al. BMC CANCER
- Transarterial chemoembolization vs bland embolization in hepatocellular carcinoma: A meta-analysis of randomized trials
- (2016) Antonio Facciorusso et al. United European Gastroenterology Journal
- MiR-122 Reverses the Doxorubicin-Resistance in Hepatocellular Carcinoma Cells through Regulating the Tumor Metabolism
- (2016) Chenwei Pan et al. PLoS One
- Tumorspheres Derived from HCC Cells are Enriched with Cancer Stem Cell-like Cells and Present High Chemoresistance Dependent on the Akt Pathway
- (2015) Xiao-Li Zhang et al. Anti-Cancer Agents in Medicinal Chemistry
- A role for cancer stem cells in therapy resistance: Cellular and molecular mechanisms
- (2015) Monica Cojoc et al. SEMINARS IN CANCER BIOLOGY
- Hepatocellular carcinoma: from hepatocyte to liver cancer stem cell
- (2015) Ioannis Karakasiliotis et al. Frontiers in Physiology
- Label-retaining liver cancer cells are relatively resistant to sorafenib
- (2013) Hong-Wu Xin et al. GUT
- Doxorubicin and 5-fluorouracil resistant hepatic cancer cells demonstrate stem-like properties
- (2012) Ngoc Bich Vu et al. CYTOTECHNOLOGY
- Investigational ABC transporter inhibitors
- (2012) Marco Falasca et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthase
- (2012) Kaustubh N. Bhinge et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- CD133+EpCAM+ Phenotype Possesses More Characteristics of Tumor Initiating Cells in Hepatocellular Carcinoma Huh7 Cells
- (2012) Yi Chen et al. International Journal of Biological Sciences
- Salinomycin as a Drug for Targeting Human Cancer Stem Cells
- (2012) Cord Naujokat et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance
- (2012) K. Meirelles et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines
- (2011) Lu Cao et al. BMC GASTROENTEROLOGY
- CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation
- (2011) Terence Kin Wah Lee et al. Cell Stem Cell
- Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma
- (2011) Satoshi Shimizu et al. INTERNATIONAL JOURNAL OF CANCER
- Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations
- (2011) Xiaoli Chen et al. JOURNAL OF HEPATOLOGY
- Cancer Stem Cells and Self-renewal
- (2010) C. A. O'Brien et al. CLINICAL CANCER RESEARCH
- Granulin-Epithelin Precursor and ATP-Dependent Binding Cassette (ABC)B5 Regulate Liver Cancer Cell Chemoresistance
- (2010) Siu Tim Cheung et al. GASTROENTEROLOGY
- P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910
- (2010) Zheng INTERNATIONAL JOURNAL OF ONCOLOGY
- CD13 is a therapeutic target in human liver cancer stem cells
- (2010) Naotsugu Haraguchi et al. JOURNAL OF CLINICAL INVESTIGATION
- Expression of multidrug resistance-associated protein 1 in hepatocellular carcinoma is associated with a more aggressive tumour phenotype and may reflect a progenitor cell origin
- (2010) Sara Vander Borght et al. LIVER INTERNATIONAL
- Doxorubicin pathways
- (2010) Caroline F. Thorn et al. Pharmacogenetics and Genomics
- Quantitative evaluation of DNA hypermethylation in malignant and benign breast tissue and fluids
- (2009) Weizhu Zhu et al. INTERNATIONAL JOURNAL OF CANCER
- EpCAM, a new marker for cancer stem cells in hepatocellular carcinoma
- (2009) Benoit Terris et al. JOURNAL OF HEPATOLOGY
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Significance of CD90+ Cancer Stem Cells in Human Liver Cancer
- (2008) Zhen Fan Yang et al. CANCER CELL
- EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features
- (2008) Taro Yamashita et al. GASTROENTEROLOGY
- Expansion of CD133-Expressing Liver Cancer Stem Cells in Liver-Specific Phosphatase and Tensin Homolog Deleted on Chromosome 10-Deleted Mice
- (2008) C. Bart Rountree et al. STEM CELLS
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