One-Pot Asymmetric Synthesis of an Aminodiol Intermediate of Florfenicol Using Engineered Transketolase and Transaminase
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
One-Pot Asymmetric Synthesis of an Aminodiol Intermediate of Florfenicol Using Engineered Transketolase and Transaminase
Authors
Keywords
-
Journal
ACS Catalysis
Volume 11, Issue 12, Pages 7477-7488
Publisher
American Chemical Society (ACS)
Online
2021-06-09
DOI
10.1021/acscatal.1c01229
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Directed Evolution of l-Threonine Aldolase for the Diastereoselective Synthesis of β-Hydroxy-α-amino Acids
- (2021) Wenlong Zheng et al. ACS Catalysis
- Biocatalysis in drug discovery and development
- (2020) Anna Fryszkowska et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Biocatalysis: Enzymatic Synthesis for Industrial Applications
- (2020) Shuke Wu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multi-enzyme cascade for improving β-hydroxy-α-amino acids production by engineering L-threonine transaldolase and combining acetaldehyde elimination system
- (2020) Lian Xu et al. BIORESOURCE TECHNOLOGY
- Enzymatic Synthesis of Aliphatic Acyloins Catalyzed by Thermostable Transketolase
- (2020) Laurence Hecquet et al. ChemCatChem
- Engineering of l-threonine aldolase for the preparation of 4-(methylsulfonyl)phenylserine, an important intermediate for the synthesis of florfenicol and thiamphenicol
- (2020) Zhicheng Liu et al. ENZYME AND MICROBIAL TECHNOLOGY
- Construction of a Highly Diastereoselective Aldol Reaction System with l-Threonine Aldolase by Computer-Assisted Rational Molecular Modification and Medium Engineering
- (2020) Wenlong Zheng et al. ORGANIC LETTERS
- A Single‐Transaminase‐Catalyzed Biocatalytic Cascade for Efficient Asymmetric Synthesis of l ‐Phosphinothricin
- (2020) Feng Cheng et al. CHEMBIOCHEM
- Methoxamine Synthesis in a Biocatalytic 1-Pot 2-Step Cascade Approach
- (2019) Vanessa Erdmann et al. ACS Catalysis
- One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases
- (2019) Tatiana P. Fedorchuk et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- One-pot, two-step transaminase and transketolase synthesis of l - gluco -heptulose from l -arabinose
- (2018) Maria Bawn et al. ENZYME AND MICROBIAL TECHNOLOGY
- Asymmetric Synthesis of Florfenicol via Dynamic Reductive Kinetic Resolution with Ketoreductases
- (2018) Jie Zou et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Biocatalytic approaches towards the stereoselective synthesis of vicinal amino alcohols
- (2018) Pankaj Gupta et al. NEW JOURNAL OF CHEMISTRY
- Recent Advances in ω-Transaminase-Mediated Biocatalysis for the Enantioselective Synthesis of Chiral Amines
- (2018) Mahesh D. Patil et al. Catalysts
- In Silico Based Engineering Approach to Improve Transaminases for the Conversion of Bulky Substrates
- (2018) Moritz Voss et al. ACS Catalysis
- Engineering a thermostable transketolase for arylated substrates
- (2017) Thangavelu Saravanan et al. GREEN CHEMISTRY
- Transaminase biocatalysis: optimization and application
- (2017) Fei Guo et al. GREEN CHEMISTRY
- Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
- (2017) David K. Romney et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Active Site Engineering of ω-Transaminase Guided by Docking Orientation Analysis and Virtual Activity Screening
- (2017) Sang-Woo Han et al. ACS Catalysis
- Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts
- (2017) Iustina Slabu et al. ACS Catalysis
- Transaminase Triggered Aza-Michael Approach for the Enantioselective Synthesis of Piperidine Scaffolds
- (2016) James Ryan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic asymmetric transfer hydrogenation/dynamic kinetic resolution: an efficient synthesis of florfenicol
- (2016) Xinlong Wang et al. TETRAHEDRON
- Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes
- (2016) Pierre E. Affaticati et al. Scientific Reports
- Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications
- (2015) Fabian Steffen-Munsberg et al. BIOTECHNOLOGY ADVANCES
- Second generation engineering of transketolase for polar aromatic aldehyde substrates
- (2015) Panwajee Payongsri et al. ENZYME AND MICROBIAL TECHNOLOGY
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- Multi-step synthesis strategies towards 1,2-amino alcohols with special emphasis on phenylpropanolamines
- (2015) Torsten Sehl et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines
- (2014) Elaine O'Reilly et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structure and functioning mechanism of transketolase
- (2014) German A. Kochetov et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Two Steps in One Pot: Enzyme Cascade for the Synthesis of Nor(pseudo)ephedrine from Inexpensive Starting Materials
- (2013) Torsten Sehl et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Engineering stereoselectivity of ThDP-dependent enzymes
- (2013) Helen C. Hailes et al. FEBS Journal
- PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
- (2013) Daniel R. Roe et al. Journal of Chemical Theory and Computation
- Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
- (2013) Romelia Salomon-Ferrer et al. Journal of Chemical Theory and Computation
- An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase
- (2012) Bo Wang et al. CHEMICAL COMMUNICATIONS
- Stereoselective Synthesis of (−)-Chloramphenicol, (+)-Thiamphenicol and (+)-Sphinganine via Chiral Tricyclic Iminolactone
- (2012) Qiong Li et al. CHINESE JOURNAL OF CHEMISTRY
- An Efficient Enantioselective Synthesis of Florfenicol Based on Sharpless Asymmetric Dihydroxylation
- (2012) Fen-Er Chen et al. SYNTHESIS-STUTTGART
- Kinetic resolution of aromatic β-amino acids by ω-transaminase
- (2011) Han-Seop Bea et al. CHEMICAL COMMUNICATIONS
- A Facile and Efficient Asymmetric Synthesis of Florfenicol
- (2011) Fen-Er Chen et al. SYNLETT
- An efficient enantioselective synthesis of florfenicol via asymmetric aziridination
- (2011) Zhonghua Wang et al. TETRAHEDRON
- An efficient enantioselective synthesis of florfenicol via a vanadium-catalyzed asymmetric epoxidation
- (2011) Feng Li et al. TETRAHEDRON-ASYMMETRY
- Immobilization of Candida rugosa lipase on glass beads for enantioselective hydrolysis of racemic Naproxen methyl ester
- (2010) Elif Yilmaz et al. BIORESOURCE TECHNOLOGY
- α,α′-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes
- (2010) James L. Galman et al. CHEMICAL COMMUNICATIONS
- The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action
- (2010) Lars Mitschke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rational assignment of key motifs for function guides in silico enzyme identification
- (2010) Matthias Höhne et al. Nature Chemical Biology
- ω-Transaminases as efficient biocatalysts to obtain novel chiral selenium-amine ligands for Pd-catalysis
- (2010) Leandro H. Andrade et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
- (2010) C. K. Savile et al. SCIENCE
- Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases
- (2008) Dominik Koszelewski et al. ADVANCED SYNTHESIS & CATALYSIS
- New stereoselective synthesis of thiamphenicol and florfenicol from enantiomerically pure cyanohydrin: a chemo-enzymatic approach
- (2008) Wenya Lu et al. TETRAHEDRON
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search