Reconstructing aspects of human embryogenesis with pluripotent stem cells

Evaluating totipotency using criteria of increasing stringency

(2021) Eszter Posfai et al.   NATURE CELL BIOLOGY

Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo

(2021) Tao Tan et al.   CELL

Human naive epiblast cells possess unrestricted lineage potential

(2021) Ge Guo et al.   Cell Stem Cell

Naive stem cell blastocyst model captures human embryo lineage segregation

(2021) Ayaka Yanagida et al.   Cell Stem Cell

Modelling human blastocysts by reprogramming fibroblasts into iBlastoids

(2021) Xiaodong Liu et al.   NATURE

Blastocyst-like structures generated from human pluripotent stem cells

(2021) Leqian Yu et al.   NATURE

Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

(2020) Susanne C. van den Brink et al.   NATURE

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

An in vitro model of early anteroposterior organization during human development

(2020) Naomi Moris et al.   NATURE

From pluripotency to totipotency: an experimentalist's guide to cellular potency

(2020) Alba Redó Riveiro et al.   DEVELOPMENT

Initiation of a conserved trophectoderm program in human, cow and mouse embryos

(2020) Claudia Gerri et al.   NATURE

Reprogramming roadmap reveals route to human induced trophoblast stem cells

(2020) Xiaodong Liu et al.   NATURE

Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro

(2020) Gianluca Amadei et al.   DEVELOPMENTAL CELL

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

(2020) Jesse V. Veenvliet et al.   SCIENCE

Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation

(2019) Joseph Massey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking

(2019) Mijo Simunovic et al.   NATURE CELL BIOLOGY

Establishment of porcine and human expanded potential stem cells

(2019) Xuefei Gao et al.   NATURE CELL BIOLOGY

MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices

(2019) Christopher S. McGinnis et al.   NATURE METHODS

Controlled modelling of human epiblast and amnion development using stem cells

(2019) Yi Zheng et al.   NATURE

Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells

(2019) Cody Kime et al.   Stem Cell Reports

Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures

(2019) Ronghui Li et al.   CELL

Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid

(2019) Berna Sozen et al.   DEVELOPMENTAL CELL

A developmental landscape of 3D-cultured human pre-gastrulation embryos

(2019) Lifeng Xiang et al.   NATURE

Derivation of Human Trophoblast Stem Cells

(2018) Hiroaki Okae et al.   Cell Stem Cell

Blastocyst-like structures generated solely from stem cells

(2018) Nicolas C. Rivron et al.   NATURE

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures

(2018) Berna Sozen et al.   NATURE CELL BIOLOGY

Deconstructing and reconstructing the mouse and human early embryo

(2018) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

(2018) Leonardo Beccari et al.   NATURE

Establishment of mouse expanded potential stem cells

(2017) Jian Yang et al.   NATURE

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

(2017) Sarah Ellys Harrison et al.   SCIENCE

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

(2017) Meng Zhu et al.   Nature Communications

Molecular Criteria for Defining the Naive Human Pluripotent State

(2016) Thorold W. Theunissen et al.   Cell Stem Cell

Low versus atmospheric oxygen tension for embryo culture in assisted reproduction: a systematic review and meta-analysis

(2016) Carolina O. Nastri et al.   FERTILITY AND STERILITY

Self-organization of the in vitro attached human embryo

(2016) Alessia Deglincerti et al.   NATURE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

(2015) Paul Blakeley et al.   DEVELOPMENT

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

(2014) S. C. van den Brink et al.   DEVELOPMENT

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

(2014) Aryeh Warmflash et al.   NATURE METHODS

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell