Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-01
DOI
10.1038/s41467-021-23590-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Copper-mediated synthesis of drug-like bicyclopentanes
- (2020) Xiaheng Zhang et al. NATURE
- Copper‐Catalyzed Deaminative Difluoromethylation
- (2020) Xiaojun Zeng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Combretastatins: An Overview of Structure, Probable Mechanisms of Action and Potential Applications
- (2020) Gökçe Şeker Karatoprak et al. MOLECULES
- Light-driven post-translational installation of reactive protein side chains
- (2020) Brian Josephson et al. NATURE
- Silver‐Enabled General Radical Difluoromethylation Reaction with TMSCF 2 H
- (2020) Jun Yang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Csp3–Csp3 Bond-Forming Reductive Elimination from Well-Defined Copper(III) Complexes
- (2019) Matthew Paeth et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Bromides with TMSCF2H
- (2019) Devin M. Ferguson et al. JOURNAL OF ORGANIC CHEMISTRY
- Copper‐Catalyzed Carbotrifluoromethylation of Unactivated Alkenes Driven by Trifluoromethylation of Alkyl Radicals
- (2019) Zhenzhen Zhang et al. CHINESE JOURNAL OF CHEMISTRY
- Photocatalyzed Cyanodifluoromethylation of Alkenes
- (2019) Min Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid
- (2019) Claudio F. Meyer et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Copper-Catalyzed Radical Aminotrifluoromethylation of Alkenes
- (2019) Haiwen Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copper-Catalyzed Decarboxylative Difluoromethylation
- (2019) Xiaojun Zeng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nickel-Catalyzed Difluoroalkylation-Alkylation of Enamides
- (2019) Chang Xu et al. ACS Catalysis
- N-Heterocyclic Carbene-Catalyzed Radical Relay Enabling Vicinal Alkylacylation of Alkenes
- (2019) Takuya Ishii et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent Progress on the Synthesis of CF2H-Containing Derivatives
- (2019) Noam Levi et al. SYNTHESIS-STUTTGART
- Chiral copper-catalyzed enantioselective Michael difluoromethylation of arylidene meldrum's acids with (difluoromethyl)zinc reagents
- (2019) Yu Endo et al. TETRAHEDRON
- Copper-Catalyzed, Chloroamide-Directed Benzylic C–H Difluoromethylation
- (2019) Xiaojun Zeng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Myth of d8 Copper(III)
- (2019) Ida M. DiMucci et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis and biological activity of fluorinated analogues of the DAF-12 receptor antagonist 24-hydroxy-4-cholen-3-one
- (2019) Cristian R. Rodriguez et al. STEROIDS
- Copper-Mediated Trifluoromethylation of Benzylic Csp3 −H Bonds
- (2018) Matthew Paeth et al. CHEMISTRY-A EUROPEAN JOURNAL
- Recent Advances in Transition Metal-Catalysed Three-Component Difunctionalization of Alkenes
- (2018) Tieqiao Chen et al. Chemistry-An Asian Journal
- A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation
- (2018) Timothée Naret et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone
- (2018) Wenjun Miao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor
- (2018) Barbara Zheng et al. ACS Medicinal Chemistry Letters
- Difluoromethylation of (hetero)aryl chlorides with chlorodifluoromethane catalyzed by nickel
- (2018) Chang Xu et al. Nature Communications
- Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations
- (2018) Fei Wang et al. ACCOUNTS OF CHEMICAL RESEARCH
- Metallaphotoredox Difluoromethylation of Aryl Bromides
- (2018) Vlad Bacauanu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct and Regioselective C–H Oxidative Difluoromethylation of Heteroarenes
- (2018) Sheng-Qing Zhu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Aqueous Benzylic C–H Trifluoromethylation for Late-Stage Functionalization
- (2018) Shuo Guo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Palladium-Catalyzed Decarbonylative Difluoromethylation of Acid Chlorides at Room Temperature
- (2018) Fei Pan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders
- (2018) Denise Rageot et al. JOURNAL OF MEDICINAL CHEMISTRY
- Visible-Light-Induced, Copper-Catalyzed Three-Component Coupling of Alkyl Halides, Olefins, and Trifluoromethylthiolate To Generate Trifluoromethyl Thioethers
- (2018) Jian He et al. ACS Catalysis
- Difluoromethyl Bioisostere: Examining the “Lipophilic Hydrogen Bond Donor” Concept
- (2017) Yossi Zafrani et al. JOURNAL OF MEDICINAL CHEMISTRY
- CF2H, a Hydrogen Bond Donor
- (2017) Chanan D. Sessler et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cu-Catalyzed Three-Component Carboamination of Alkenes
- (2017) Samuel N. Gockel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium
- (2017) Zhang Feng et al. Nature Chemistry
- Synthesis, Reactivity, and Catalytic Applications of Isolable (NHC)Cu(CHF2) Complexes
- (2017) James R. Bour et al. ORGANOMETALLICS
- Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides
- (2017) Changhui Lu et al. Chemical Science
- Metal-Catalyzed Direct Difluoromethylation Reactions
- (2017) Jian Rong et al. Asian Journal of Organic Chemistry
- Antioxidant properties in a non-polar environment of difluoromethyl bioisosteres of methyl hydroxycinnamates
- (2016) Mario D. Martínez et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Direct Difluoromethylation of Aryl Halides via Base Metal Catalysis at Room Temperature
- (2016) Long Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copper-Catalyzed Difluoromethylation of Aryl Iodides with (Difluoromethyl)zinc Reagent
- (2016) Hiroki Serizawa et al. ORGANIC LETTERS
- A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents
- (2016) T. Qin et al. SCIENCE
- Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay
- (2016) Wen Zhang et al. SCIENCE
- Recent Advances in Meerwein Arylation Chemistry
- (2016) Markus Heinrich et al. SYNTHESIS-STUTTGART
- Visible-Light-Induced Hydrodifluoromethylation of Alkenes with a Bromodifluoromethylphosphonium Bromide
- (2015) Qing-Yu Lin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct Photoredox-Catalyzed Reductive Difluoromethylation of Electron-Deficient Alkenes
- (2015) Xiao-Jun Tang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Recent Advances in Difluoromethylation Reaction
- (2015) Yang Lu et al. CURRENT ORGANIC CHEMISTRY
- Well-Defined, Shelf-Stable (NHC)Ag(CF2H) Complexes for Difluoromethylation
- (2015) Yang Gu et al. ORGANOMETALLICS
- Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups
- (2014) Hiromichi Egami et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
- (2014) Edon Vitaku et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sandmeyer Difluoromethylation of (Hetero-)Arenediazonium Salts
- (2014) Christian Matheis et al. ORGANIC LETTERS
- Cooperative dual palladium/silver catalyst for direct difluoromethylation of aryl bromides and iodides
- (2014) Yang Gu et al. Nature Communications
- Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
- (2013) Jiang Wang et al. CHEMICAL REVIEWS
- Copper-Mediated Difluoromethylation of (Hetero)aryl Iodides and β-Styryl Halides with Tributyl(difluoromethyl)stannane
- (2012) G. K. Surya Prakash et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A New Reagent for Direct Difluoromethylation
- (2012) Yuta Fujiwara et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copper-Mediated Difluoromethylation of Aryl and Vinyl Iodides
- (2012) Patrick S. Fier et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
- (2011) Nicholas A. Meanwell JOURNAL OF MEDICINAL CHEMISTRY
- Catalysis for fluorination and trifluoromethylation
- (2011) Takeru Furuya et al. NATURE
- Fluorine in medicinal chemistry
- (2007) Sophie Purser et al. CHEMICAL SOCIETY REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More