Copper‐Catalyzed Carbotrifluoromethylation of Unactivated Alkenes Driven by Trifluoromethylation of Alkyl Radicals

Copper-Catalyzed Remote C(sp3 )−H Trifluoromethylation of Carboxamides and Sulfonamides

(2019) Zhonglin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Csp3–Csp3 Bond-Forming Reductive Elimination from Well-Defined Copper(III) Complexes

(2019) Matthew Paeth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oximinotrifluoromethylation of Unactivated Alkenes under Ambient Conditions

(2018) Na Wang et al.   CHEMICAL COMMUNICATIONS

Copper-Mediated Trifluoromethylation of Benzylic Csp3 −H Bonds

(2018) Matthew Paeth et al.   CHEMISTRY-A EUROPEAN JOURNAL

Radical Carbofluorination of Unactivated Alkenes with Fluoride Ions

(2018) Zhonglin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2018) Jacob A. Kautzky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Promoted Cascade Alkene Trifluoromethylation and Dearomatization of Indole Derivatives via Intermolecular Charge Transfer

(2018) Min Zhu et al.   ORGANIC LETTERS

Copper-catalyzed Intramolecular Carbotrifluoromethylation of Ene-Imines for the Construction of 3-(2,2,2-Trifluoro)ethylated 4-Amino-Chromans

(2018) Qin Ye et al.   ADVANCED SYNTHESIS & CATALYSIS

Carbotrifluoromethylation of Allylic Alcohols via 1,2-Aryl Migration Promoted by Visible-Light-Induced Photoredox Catalysis

(2018) Shunyou Cai et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocopper(III) Compounds with Well-defined Structures Undergo Reductive Elimination to Form C-C or C-Heteroatom Bonds

(2018) Liang Liu et al.   CHINESE JOURNAL OF CHEMISTRY

Synthesis of CF3CH2-Containing Indolines by Transition-Metal-Free Aryltrifluoromethylation of Unactivated Alkenes

(2018) Deqiang Liang et al.   JOURNAL OF ORGANIC CHEMISTRY

Aqueous Benzylic C–H Trifluoromethylation for Late-Stage Functionalization

(2018) Shuo Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Three-Component Difunctionalization of Alkenes via Radical Pathways: Access to CF3-Functionalized Alkyl-Substituted 1,4-Naphthoquinone Derivatives

(2018) Qijun Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

K2S2O8-Mediated Selective Trifluoromethylacylation and Trifluoromethylarylation of Alkenes under Transition-Metal-Free Conditions: Synthetic Scope and Mechanistic Studies

(2018) Lin Tang et al.   ORGANIC LETTERS

Trifluoromethylation of Alkyl Radicals in Aqueous Solution

(2017) Haigen Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2017) Xinqiang Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Radical Trifluoromethylalkynylation of Unactivated Alkenes

(2017) Shaofang Zhou et al.   ORGANIC LETTERS

Radical Alkynyltrifluoromethylation of Alkenes Initiated by an Electron Donor–Acceptor Complex

(2017) Heng Jiang et al.   ORGANIC LETTERS

A remote C–C bond cleavage–enabled skeletal reorganization: Access to medium-/large-sized cyclic alkenes

(2017) Lei Li et al.   Science Advances

Fine Design of Photoredox Systems for Catalytic Fluoromethylation of Carbon–Carbon Multiple Bonds

(2016) Takashi Koike et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Catalyzed Divergent Trifluoromethylation/Cyclization of Unactivated Alkenes

(2016) Jing Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Organic base-catalysed solvent-tuned chemoselective carbotrifluoromethylation and oxytrifluoromethylation of unactivated alkenes

(2016) Ning-Yuan Yang et al.   CHEMICAL COMMUNICATIONS

Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process

(2016) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TfNHNHBoc as a Trifluoromethylating Agent for Vicinal Difunctionalization of Terminal Alkenes

(2016) Jing-Yu Guo et al.   ORGANIC LETTERS

Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings

(2016) Lei Li et al.   Nature Communications

Visible-Light Photoredox-Catalyzed Semipinacol-Type Rearrangement: Trifluoromethylation/Ring Expansion by a Radical-Polar Mechanism

(2015) Basudev Sahoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible light promoted carbodifluoroalkylation of allylic alcohols via concomitant 1,2-aryl migration

(2015) Pan Xu et al.   CHEMICAL COMMUNICATIONS

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Difunctionalization of Alkenes via the Visible-Light-Induced Trifluoromethylarylation/1,4-Aryl Shift/Desulfonylation Cascade Reactions

(2015) Lewei Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Development of (Trifluoromethyl)zinc Reagent as Trifluoromethyl Anion and Difluorocarbene Sources

(2015) Kohsuke Aikawa et al.   ORGANIC LETTERS

Copper-Mediated Radical 1,2-Bis(trifluoromethylation) of Alkenes with Sodium Trifluoromethanesulfinate

(2015) Bin Yang et al.   ORGANIC LETTERS

Iron- or Copper-Catalyzed Trifluoromethylation of Acrylamide-Tethered Alkylidenecyclopropanes: Facile Synthesis of CF3-Containing Polycyclic Benzazepine Derivatives

(2015) Liu-Zhu Yu et al.   ACS Catalysis

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One pot and selective intermolecular aryl- and heteroaryl-trifluoromethylation of alkenes by photoredox catalysis

(2014) Aude Carboni et al.   CHEMICAL COMMUNICATIONS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Addition of CF3 across unsaturated moieties: a powerful functionalization tool

(2014) Estíbaliz Merino et al.   CHEMICAL SOCIETY REVIEWS

Stable but Reactive Perfluoroalkylzinc Reagents: Application in Ligand-Free Copper-Catalyzed Perfluoroalkylation of Aryl Iodides

(2014) Kohsuke Aikawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Distinct Mechanism of Oxidative Trifluoromethylation with a Well-Defined Cu(II) Fluoride Promoter: Hidden Catalysis

(2014) Noel Nebra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent

(2014) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethylation by Visible-Light-Driven Photoredox Catalysis

(2014) Takashi Koike et al.   TOPICS IN CATALYSIS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

(2010) Norio Shibata et al.   Beilstein Journal of Organic Chemistry

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Catalyst Regeneration in Transition-Metal-Mediated Atom-Transfer Radical Addition (ATRA) and Cyclization (ATRC) Reactions

(2010) Tomislav Pintauer   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Recent advances in enantioselective trifluoromethylation reactions

(2009) Norio Shibata et al.   TETRAHEDRON-ASYMMETRY