Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

(2021) Caillan Crowe-McAuliffe et al.   Nature Communications

A Chemical Counterpunch: Chromobacterium violaceum ATCC 31532 Produces Violacein in Response to Translation-Inhibiting Antibiotics

(2020) Gabriel L. Lozano et al.   mBio

Ribosome-Mediated Attenuation of vga(A) Expression Is Shaped by the Antibiotic Resistance Specificity of Vga(A) Protein Variants

(2020) Vladimir Vimberg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems

(2020) Arunkumar Krishnan et al.   NUCLEIC ACIDS RESEARCH

LmbU, a Cluster-Situated Regulator for Lincomycin, Consists of a DNA-Binding Domain, an Auto-Inhibitory Domain, and Forms Homodimer

(2019) Bingbing Hou et al.   Frontiers in Microbiology

ABC-F proteins in mRNA translation and antibiotic resistance

(2019) Farés Ousalem et al.   RESEARCH IN MICROBIOLOGY

Developmental regulator BldD directly regulates lincomycin biosynthesis in Streptomyces lincolnensis

(2019) Jie Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis

(2019) Yajing Kang et al.   Frontiers in Microbiology

Regulation of Antibiotic Production by Signaling Molecules in Streptomyces

(2019) Dekun Kong et al.   Frontiers in Microbiology

Control of Specialized Metabolism by Signaling and Transcriptional Regulation: Opportunities for New Platforms for Drug Discovery?

(2018) M. Daniel-Ivad et al.   Annual Review of Microbiology

A possible mechanism for lincomycin induction of secondary metabolism in Streptomyces coelicolor A3(2)

(2018) Misaki Ishizuka et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

G4PromFinder: an algorithm for predicting transcription promoters in GC-rich bacterial genomes based on AT-rich elements and G-quadruplex motifs

(2018) Marco Di Salvo et al.   BMC BIOINFORMATICS

Enhanced lincomycin production by co-overexpression of metK1 and metK2 in Streptomyces lincolnensis

(2018) Yurong Xu et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

(2018) Helga U. van der Heul et al.   NATURAL PRODUCT REPORTS

Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products

(2018) J. Janata et al.   NATURAL PRODUCT REPORTS

Ribosome protection by antibiotic resistance ATP-binding cassette protein

(2018) Weixin Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR

(2018) Caillan Crowe-McAuliffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

(2018) Victoriia Murina et al.   JOURNAL OF MOLECULAR BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis

(2017) Bingbing Hou et al.   JOURNAL OF BACTERIOLOGY

1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life

(2017) Supratim Mukherjee et al.   NATURE BIOTECHNOLOGY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Ribosome hibernation factor promotesStaphylococcalsurvival and differentially represses translation

(2016) Arnab Basu et al.   NUCLEIC ACIDS RESEARCH

Computational prediction of regulatory, premature transcription termination in bacteria

(2016) Adi Millman et al.   NUCLEIC ACIDS RESEARCH

Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria

(2016) D. Dar et al.   SCIENCE

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection

(2016) Liam K. R. Sharkey et al.   mBio

Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.

(2015) Yu Imai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Lincosamide Synthetase—A Unique Condensation System Combining Elements of Nonribosomal Peptide Synthetase and Mycothiol Metabolism

(2015) Jiri Janata et al.   PLoS One

Socially mediated induction and suppression of antibiosis during bacterial coexistence

(2015) Monica I. Abrudan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides

(2015) Mashal M. Almutairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Attenuation Controls Macrolide Inducible Efflux and Resistance in Streptococcus pneumoniae and in Other Gram-Positive Bacteria Containing mef/mel(msr(D)) Elements

(2015) Scott T. Chancey et al.   PLoS One

Detailed Mutational Analysis of Vga(A) Interdomain Linker: Implication for Antibiotic Resistance Specificity and Mechanism

(2014) Jakub Lenart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sequence analysis of porothramycin biosynthetic gene cluster

(2014) Lucie Najmanova et al.   FOLIA MICROBIOLOGICA

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

The expression of antibiotic resistance genes in antibiotic-producing bacteria

(2014) Stefanie Mak et al.   MOLECULAR MICROBIOLOGY

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

(2014) Grégory Boël et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics

(2014) Bo Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Impact of interspecific interactions on antimicrobial activity among soil bacteria

(2014) Olaf Tyc et al.   Frontiers in Microbiology

Manipulation of Regulatory Genes Reveals Complexity and Fidelity in Hormaomycin Biosynthesis

(2013) Xiaofeng Cai et al.   CHEMISTRY & BIOLOGY

The One Hour Yeast Proteome

(2013) Alexander S. Hebert et al.   MOLECULAR & CELLULAR PROTEOMICS

Competition sensing: the social side of bacterial stress responses

(2013) Daniel M. Cornforth et al.   NATURE REVIEWS MICROBIOLOGY

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

The antibiotic planosporicin coordinates its own production in the actinomycete Planomonospora alba

(2013) E. J. Sherwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the Mildiomycin Biosynthesis Gene Cluster in Streptoverticillum remofaciens ZJU5119 and Characterization of MilC, a Hydroxymethyl cytosyl-glucuronic Acid Synthase

(2012) Jun Wu et al.   CHEMBIOCHEM

SLiCE: a novel bacterial cell extract-based DNA cloning method

(2012) Yongwei Zhang et al.   NUCLEIC ACIDS RESEARCH

A Two-Step Mechanism for the Activation of Actinorhodin Export and Resistance in Streptomyces coelicolor

(2012) Y. Xu et al.   mBio

Insights into the Biosynthesis of Hormaomycin, An Exceptionally Complex Bacterial Signaling Metabolite

(2011) Ivonne Höfer et al.   CHEMISTRY & BIOLOGY

Pathway engineering via quorum sensing and sRNA riboregulators—Interconnected networks and controllers

(2011) Karen K. Carter et al.   METABOLIC ENGINEERING

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Transcriptional regulation of the novobiocin biosynthetic gene cluster

(2009) V. Dangel et al.   MICROBIOLOGY-SGM

Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone inStreptomyces antibioticus

(2009) Tung B. K. Le et al.   MOLECULAR MICROBIOLOGY

Coordination of export and glycosylation of landomycins inStreptomyces cyanogenusS136

(2008) Iryna Ostash et al.   FEMS MICROBIOLOGY LETTERS

Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466

(2008) M. Koběrská et al.   FOLIA MICROBIOLOGICA

Phase Transfer Surfactant-Aided Trypsin Digestion for Membrane Proteome Analysis

(2008) Takeshi Masuda et al.   JOURNAL OF PROTEOME RESEARCH