The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis

Challenges in Targeting a Basic Helix–Loop–Helix Transcription Factor with Hydrocarbon-Stapled Peptides

(2016) Amanda L. Edwards et al.   ACS Chemical Biology

Interspecies Complementation of the LuxR Family Pathway-Specific Regulator Involved in Macrolide Biosynthesis

(2016) SangJoon Mo et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

New Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a γ-Glutamyltransferase Cleave the C–C Bond?

(2016) Petra Jiraskova et al.   Frontiers in Microbiology

Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product

(2015) Wenshuai Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Co-overexpression oflmbWandmetKled to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain ofStreptomyces lincolnensis

(2015) A.-P. Pang et al.   JOURNAL OF APPLIED MICROBIOLOGY

Binding of a biosynthetic intermediate to AtrA modulates the production of lidamycin byStreptomyces globisporus

(2015) Xingxing Li et al.   MOLECULAR MICROBIOLOGY

Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A

(2015) Qunfei Zhao et al.   NATURE

Nitrogen regulator GlnR controls uptake and utilization of non-phosphotransferase-system carbon sources in actinomycetes

(2015) Cheng-Heng Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Coronafacoyl Phytotoxin Production by the PAS-LuxR Family Regulator CfaR in the Common Scab Pathogen Streptomyces scabies

(2015) Zhenlong Cheng et al.   PLoS One

Differential contributions of two SARP family regulatory genes to indigoidine biosynthesis in Streptomyces lavendulae FRI-5

(2014) Yohanes Novi Kurniawan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

In Vitro Characterization of LmbK and LmbO: Identification of GDP-d-erythro-α-d-gluco-octose as a Key Intermediate in Lincomycin A Biosynthesis

(2014) Chia-I Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of SAV7471, a TetR-Family Transcriptional Regulator Involved in the Regulation of Coenzyme A Metabolism in Streptomyces avermitilis

(2013) Y. Liu et al.   JOURNAL OF BACTERIOLOGY

Complex Structure of the DNA-binding Domain of AdpA, the Global Transcription Factor inStreptomyces griseus, and a Target Duplex DNA Reveals the Structural Basis of Its Tolerant DNA Sequence Specificity

(2013) Ming Dong Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The transcriptional regulator TamR fromStreptomyces coelicolorcontrols a key step in central metabolism during oxidative stress

(2013) Hao Huang et al.   MOLECULAR MICROBIOLOGY

JadR*-mediated feed-forward regulation of cofactor supply in jadomycin biosynthesis

(2013) Yanyan Zhang et al.   MOLECULAR MICROBIOLOGY

Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors

(2013) Jennifer R. Davis et al.   NUCLEIC ACIDS RESEARCH

The C-terminal domain of the transcriptional regulator BldD fromStreptomyces coelicolorA3(2) constitutes a novel fold of winged-helix domains

(2013) Jeong-Mok Kim et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Construction of the Octose 8-Phosphate Intermediate in Lincomycin A Biosynthesis: Characterization of the Reactions Catalyzed by LmbR and LmbN

(2012) Eita Sasaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas aeruginosa Virulence Genes

(2012) Edward E. Pryor et al.   PLoS Pathogens

Insights into the Biosynthesis of Hormaomycin, An Exceptionally Complex Bacterial Signaling Metabolite

(2011) Ivonne Höfer et al.   CHEMISTRY & BIOLOGY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

DNA recognition and transcriptional regulation by the WhiA sporulation factor

(2011) Brett K. Kaiser et al.   Scientific Reports

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

(2010) Juan-Francisco Martín et al.   CURRENT OPINION IN MICROBIOLOGY

Cloning and Characterization of the Biosynthetic Gene Cluster for Tomaymycin, an SJG-136 Monomeric Analog

(2009) W. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of Sibiromycin, a Potent Antitumor Antibiotic

(2009) W. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466

(2008) M. Koběrská et al.   FOLIA MICROBIOLOGICA

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production inStreptomyces coelicolor

(2008) Sean O'Rourke et al.   MOLECULAR MICROBIOLOGY