Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides

Substrate Controlled Divergence in Polyketide Synthase Catalysis

(2015) Douglas A. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The general mode of translation inhibition by macrolide antibiotics

(2014) Krishna Kannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrolide antibiotics allosterically predispose the ribosome for translation arrest

(2014) Shanmugapriya Sothiselvam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence selectivity of macrolide-induced translational attenuation

(2014) A. R. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin

(2013) Douglas A. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible

(2013) Pulkit Gupta et al.   Nature Communications

The last rRNA methyltransferase of E. coli revealed: The yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA

(2012) A. Y. Golovina et al.   RNA

Antibiotics in development targeting protein synthesis

(2011) Joyce A. Sutcliffe   Annals of the New York Academy of Sciences

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

(2011) N. Vazquez-Laslop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

(2010) Nora Vázquez-Laslop et al.   EMBO JOURNAL

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

(2010) J. A. Dunkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the structures of several antibiotics bound to the bacterial ribosome

(2010) D. Bulkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmed drug-dependent ribosome stalling

(2009) Haripriya Ramu et al.   MOLECULAR MICROBIOLOGY

The methymycin/pikromycin pathway: A model for metabolic diversity in natural product biosynthesis

(2008) Jeffrey D. Kittendorf et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Update on macrolide-lincosamide-streptogramin, ketolide, and oxazolidinone resistance genes

(2008) Marilyn C. Roberts   FEMS MICROBIOLOGY LETTERS

Molecular Mechanism of Drug-Dependent Ribosome Stalling

(2008) Nora Vazquez-Laslop et al.   MOLECULAR CELL