Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence

Mononuclear phagocytic system and fibrosis: back to the future?

(2021) Kjetil Ask et al.   EUROPEAN RESPIRATORY JOURNAL

UUO induces lung fibrosis with macrophage-myofibroblast transition in rats

(2021) Fan Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Blood monocyte counts as a potential prognostic marker for IPF: Analysis from the Australian IPF registry

(2020) Alan K. Y. Teoh et al.   EUROPEAN RESPIRATORY JOURNAL

Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis

(2020) Filipa Lopes-Coelho et al.   Cells

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

(2020) Sarah Bowling et al.   CELL

Intraglomerular Monocyte/Macrophage Infiltration and Macrophage–Myofibroblast Transition during Diabetic Nephropathy Is Regulated by the A2B Adenosine Receptor

(2020) Ángelo Torres et al.   Cells

The Emerging Role of Innate Immunity in Chronic Kidney Diseases

(2020) Philip Chiu-Tsun Tang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage–myofibroblast transition

(2020) Patrick Ming-Kuen Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress induces monocyte‐to‐myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma

(2020) Xin Huang et al.   Clinical and Translational Medicine

Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

(2020) Kasha P. Singh et al.   PLoS Pathogens

FK506-binding Protein 13 Expression is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity: A Potentially Protective Role

(2020) Victor Tat et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Deciphering the cellular mechanisms underlying fibrosis-associated diseases and therapeutic avenues

(2020) Hua Miao et al.   PHARMACOLOGICAL RESEARCH

Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation

(2020) Stephanie Evans et al.   PLoS Computational Biology

Macrophage and Fibroblast Interactions in Biomaterial-Mediated Fibrosis

(2019) Claire E. Witherel et al.   Advanced Healthcare Materials

Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases: a retrospective, multicentre cohort study

(2019) Madeleine K D Scott et al.   Lancet Respiratory Medicine

Macrophages: versatile players in renal inflammation and fibrosis

(2019) Patrick Ming-Kuen Tang et al.   Nature Reviews Nephrology

Transcription Factor MafB Suppresses Type I Interferon Production by CD14+ Monocytes in Patients With Chronic Hepatitis C

(2019) Tie-Mei Liu et al.   Frontiers in Microbiology

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney

(2019) Swayam Prakash Srivastava et al.   Frontiers in Pharmacology

In vivo Differentiation of Human Monocytes

(2019) Alice Coillard et al.   Frontiers in Immunology

Protein Misfolding and ER stress in Chronic Lung Disease: Will Cell-Specific Targeting be the Key to the Cure?

(2019) Safaa Naiel et al.   CHEST

Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction

(2019) Nezam Haider et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Epigenetic Control of CXCL10: Regulating the Counterregulator in Idiopathic Pulmonary Fibrosis

(2018) Jesse Roman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pharmacological inhibition of Rac1 exerts a protective role in ischemia/reperfusion-induced renal fibrosis

(2018) Hua Liang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibroblast heterogeneity: implications for human disease

(2018) Magnus D. Lynch et al.   JOURNAL OF CLINICAL INVESTIGATION

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring

(2018) Patrick Ming-Kuen Tang et al.   KIDNEY INTERNATIONAL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

A new and efficient culture method for porcine bone marrow-derived M1- and M2-polarized macrophages

(2018) Jiye Gao et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Cardiac fibrosis: new insights into the pathogenesis

(2018) Zhen-Guo Ma et al.   International Journal of Biological Sciences

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Inhibition of Wnt/β-catenin signaling suppresses myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis

(2018) Honghui Cao et al.   Scientific Reports

Fate alteration of bone marrow-derived macrophages ameliorates kidney fibrosis in murine model of unilateral ureteral obstruction

(2018) Ying Yang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

(2017) Ying-Ying Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection

(2017) Hayley C. Warsinske et al.   JOURNAL OF THEORETICAL BIOLOGY

Fibroblasts: Diverse Cells Critical to Biomaterials Integration

(2017) Riley T. Hannan et al.   ACS Biomaterials-Science & Engineering

Fibroblasts: Diverse Cells Critical to Biomaterials Integration

(2017) Riley T. Hannan et al.   ACS Biomaterials Science & Engineering

Myofibroblasts

(2016) Boris Hinz   EXPERIMENTAL EYE RESEARCH

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

(2016) Xiao-Ming Meng et al.   Cell Death & Disease

Role of Bone Marrow-Derived Fibroblasts in Renal Fibrosis

(2016) Jingyin Yan et al.   Frontiers in Physiology

p38 MAPK inhibition alleviates experimental acute pancreatitis in mice

(2015) Ming-Hua Cao et al.   Hepatobiliary & Pancreatic Diseases International

TGF-β/Smad3 signalling regulates the transition of bone marrowderived macrophages into myofibroblasts during tissue fibrosis

(2015) Shuang Wang et al.   Oncotarget

TGF-β/Smad signaling in renal fibrosis

(2015) Xiao-Ming Meng et al.   Frontiers in Physiology

From the Reticuloendothelial to Mononuclear Phagocyte System – The Unaccounted Years

(2015) Simon Yona et al.   Frontiers in Immunology

M2 Polarization of Human Macrophages Favors Survival of the Intracellular Pathogen Chlamydia pneumoniae

(2015) Tanja Buchacher et al.   PLoS One

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Monitoring fibrogenic progression in the liver

(2014) Olav A. Gressner et al.   CLINICA CHIMICA ACTA

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Chitinase 3-Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis

(2014) Y. Zhou et al.   Science Translational Medicine

Macrophages promote renal fibrosis through direct and indirect mechanisms

(2014) David J. Nikolic-Paterson et al.   Kidney International Supplements

Cellular Mechanisms of Tissue Fibrosis. 3. Novel mechanisms of kidney fibrosis

(2013) Gabriela Campanholle et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models

(2013) Gissela B Lieber et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Adenosine A2B receptor-mediated VEGF induction promotes diabetic glomerulopathy

(2012) Angel Cárdenas et al.   LABORATORY INVESTIGATION

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

(2011) Michael A. Gibbons et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype

(2010) Susan K Mathai et al.   LABORATORY INVESTIGATION

Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis

(2009) Antje Moeller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats

(2009) H. Roa et al.   FEBS LETTERS

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Rac Inhibition Reverses the Phenotype of Fibrotic Fibroblasts

(2009) Xu Shi-wen et al.   PLoS One

Differentiation and heterogeneity in the mononuclear phagocyte system

(2008) D A Hume   Mucosal Immunology