Recent Advances in 2D Material‐Mediated Immuno‐Combined Cancer Therapy

A glutathione responsive nanoplatform made of reduced graphene oxide and MnO2 nanoparticles for photothermal and chemodynamic combined therapy

(2021) Baojin Ma et al.   CARBON

Two-Dimensional Nanomaterials for Photothermal Therapy

(2020) Shuang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In situ Photothermal Activation of Necroptosis Potentiates Black Phosphorus-Mediated Cancer Photo-Immunotherapy

(2020) Henan Zhao et al.   CHEMICAL ENGINEERING JOURNAL

A Heterojunction Structured WO2.9-WSe2 Nanoradiosensitizer Increases Local Tumor Ablation and Checkpoint Blockade Immunotherapy upon Low Radiation Dose

(2020) Xinghua Dong et al.   ACS Nano

Immunological Responses Induced by Blood Protein Coronas on Two-Dimensional MoS2 Nanosheets

(2020) Didar Baimanov et al.   ACS Nano

Improving Cancer Immunotherapy Outcomes using Biomaterials

(2020) Xiaogang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy

(2020) Matteo Andrea Lucherelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immunostimulatory Potential of MoS2 Nanosheets: Enhancing Dendritic Cell Maturation, Migration and T Cell Elicitation

(2020) Lei Deng et al.   International Journal of Nanomedicine

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

Safe‐by‐Design Exfoliation of Niobium Diselenide Atomic Crystals as a Theory‐Oriented 2D Nanoagent from Anti‐Inflammation to Antitumor

(2020) Zhaohua Miao et al.   ADVANCED FUNCTIONAL MATERIALS

Polarization and function of tumor-associated macrophages mediate graphene oxide-induced photothermal cancer therapy

(2020) Xiangyu Deng et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Nanoscale Metal–Organic Framework Co-delivers TLR-7 Agonists and Anti-CD47 Antibodies to Modulate Macrophages and Orchestrate Cancer Immunotherapy

(2020) Kaiyuan Ni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoenzyme-Reinforced Injectable Hydrogel for Healing Diabetic Wounds Infected with Multidrug Resistant Bacteria

(2020) Shenqiang Wang et al.   NANO LETTERS

Nanoscale Metal–Organic Frameworks for Cancer Immunotherapy

(2020) Kaiyuan Ni et al.   ACCOUNTS OF CHEMICAL RESEARCH

Efficient Lymph Node-Targeted Delivery of Personalized Cancer Vaccines with Reactive Oxygen Species-Inducing Reduced Graphene Oxide Nanosheets

(2020) Cheng Xu et al.   ACS Nano

Bimetallic Oxide FeWO X Nanosheets as Multifunctional Cascade Bioreactors for Tumor Microenvironment‐Modulation and Enhanced Multimodal Cancer Therapy

(2020) Fei Gong et al.   ADVANCED FUNCTIONAL MATERIALS

Ultra-dispersed biomimetic nanoplatform fabricated by controlled etching agglomerated MnO2 for enhanced photodynamic therapy and immune activation

(2020) Qianyuan He et al.   CHEMICAL ENGINEERING JOURNAL

Controlled release of immunotherapeutics for enhanced cancer immunotherapy after local delivery

(2020) Qiutong Jin et al.   JOURNAL OF CONTROLLED RELEASE

Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy

(2020) Zhongjian Xie et al.   Light-Science & Applications

Combinatorial Photothermal 3D‐Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis

(2020) Chao He et al.   ADVANCED FUNCTIONAL MATERIALS

Improving safety of cancer immunotherapy via delivery technology

(2020) Doudou Hu et al.   BIOMATERIALS

Intelligent MoS2–CuO heterostructures with multiplexed imaging and remarkably enhanced antitumor efficacy via synergetic photothermal therapy/ chemodynamic therapy/ immunotherapy

(2020) Fan Jiang et al.   BIOMATERIALS

Host Immune Response Triggered by Graphene Quantum-Dot-Mediated Photodynamic Therapy for Oral Squamous Cell Carcinoma

(2020) Xiliu Zhang et al.   International Journal of Nanomedicine

Preparation and in Vitro Antitumor Study of Two-Dimensional Muscovite Nanosheets

(2020) Tian Xia et al.   LANGMUIR

Bioengineering of nano metal-organic frameworks for cancer immunotherapy

(2020) Gaowei Chong et al.   Nano Research

Inorganic nanoparticles in clinical trials and translations

(2020) Hui Huang et al.   Nano Today

Modulating macrophage activities to promote endogenous bone regeneration: Biological mechanisms and engineering approaches

(2020) Yiming Niu et al.   Bioactive Materials

Recent advances of two-dimensional materials in smart drug delivery nano-systems

(2020) Hua Zhang et al.   Bioactive Materials

Nano-immunotherapy: Unique mechanisms of nanomaterials in synergizing cancer immunotherapy

(2020) Quan Liu et al.   Nano Today

Evaluating the Surface Chemistry of Black Phosphorus during Ambient Degradation

(2019) Maart van Druenen et al.   LANGMUIR

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Nanoparticle‐Based Nanomedicines to Promote Cancer Immunotherapy: Recent Advances and Future Directions

(2019) Jianping Liu et al.   Small

Designing Bioinspired 2D MoSe 2 Nanosheet for Efficient Photothermal‐Triggered Cancer Immunotherapy with Reprogramming Tumor‐Associated Macrophages

(2019) Lizhen He et al.   ADVANCED FUNCTIONAL MATERIALS

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

(2019) Filipe Martins et al.   Nature Reviews Clinical Oncology

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Method for the Instant In-Flight Manufacture of Black Phosphorus to Assemble Core@Shell Nanocomposites for Targeted Photoimmunotherapy

(2019) Hanh Thuy Nguyen et al.   ACS Applied Materials & Interfaces

2D Nanomaterials for Cancer Theranostic Applications

(2019) Liang Cheng et al.   ADVANCED MATERIALS

Highly efficient cascading synergy of cancer photo-immunotherapy enabled by engineered graphene quantum dots/photosensitizer/CpG oligonucleotides hybrid nanotheranostics

(2019) Chunhui Wu et al.   BIOMATERIALS

Immune checkpoint inhibitor therapy in solid organ transplant recipients: A patient-centered systematic review

(2019) Juliya Fisher et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy

(2019) Kaiyuan Ni et al.   Chem

A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy

(2019) Cristina Martín et al.   ADVANCED FUNCTIONAL MATERIALS

Covalent Organic Framework‐Supported Molecularly Dispersed Near‐Infrared Dyes Boost Immunogenic Phototherapy against Tumors

(2019) Shaoju Gan et al.   ADVANCED FUNCTIONAL MATERIALS

Two-dimensional nanomaterials:fascinating materials in biomedical field

(2019) Tingting Hu et al.   Science Bulletin

Enzymatic Degradation of Graphene Quantum Dots by Human Peroxidases

(2019) Cristina Martín et al.   Small

Emerging 2D material-based nanocarrier for cancer therapy beyond graphene

(2019) Yingwei Wang et al.   COORDINATION CHEMISTRY REVIEWS

Dual Roles of Graphene Oxide To Attenuate Inflammation and Elicit Timely Polarization of Macrophage Phenotypes for Cardiac Repair

(2018) Jin Han et al.   ACS Nano

3D-printed IFN-γ-loading calcium silicate-β-tricalcium phosphate scaffold sequentially activates M1 and M2 polarization of macrophages to promote vascularization of tissue engineering bone

(2018) Tao Li et al.   Acta Biomaterialia

A Novel Top-Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging-Guided Cancer Therapy

(2018) Xiaoyuan Ji et al.   ADVANCED MATERIALS

A Cisplatin-Loaded Immunochemotherapeutic Nanohybrid Bearing Immune Checkpoint Inhibitors for Enhanced Cervical Cancer Therapy

(2018) Na Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-dimensional tellurium nanosheets for photoacoustic imaging-guided photodynamic therapy

(2018) Yan Lin et al.   CHEMICAL COMMUNICATIONS

Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors

(2018) Kristian M. Hargadon et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of Human Natural Killer Cells by Graphene Oxide-Templated Antibody Nanoclusters

(2018) Christian Loftus et al.   NANO LETTERS

Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

(2018) Kaiyuan Ni et al.   Nature Communications

Revealing the immune perturbation of black phosphorus nanomaterials to macrophages by understanding the protein corona

(2018) Jianbin Mo et al.   Nature Communications

Material Chemistry of Two-Dimensional Inorganic Nanosheets in Cancer Theranostics

(2018) Bowen Yang et al.   Chem

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model

(2018) Sung Won Lee et al.   Scientific Reports

Nanoscale Reduced Graphene Oxide-Mediated Photothermal Therapy Together with IDO Inhibition and PD-L1 Blockade Synergistically Promote Antitumor Immunity

(2018) Mengmeng Yan et al.   ACS Applied Materials & Interfaces

Alum-functionalized graphene oxide nanocomplexes for effective anticancer vaccination

(2018) Xiaoli Wang et al.   Acta Biomaterialia

Self-Assembled Copper–Amino Acid Nanoparticles for in Situ Glutathione “AND” H2O2 Sequentially Triggered Chemodynamic Therapy

(2018) Baojin Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CpG loaded MoS2 nanosheets as multifunctional agents for photothermal enhanced cancer immunotherapy

(2017) Qiusen Han et al.   Nanoscale

PEGylated graphene oxide elicits strong immunological responses despite surface passivation

(2017) Nana Luo et al.   Nature Communications

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

(2017) Sourav P. Mukherjee et al.   Nanoscale

Biomedical Uses for 2D Materials Beyond Graphene: Current Advances and Challenges Ahead

(2016) Rajendra Kurapati et al.   ADVANCED MATERIALS

Soluble and immobilized graphene oxide activates complement system differently dependent on surface oxidation state

(2016) Peter P. Wibroe et al.   BIOMATERIALS

Transition metal based layered double hydroxides tailored for energy conversion and storage

(2016) Xia Long et al.   Materials Today

Two-dimensional non-carbonaceous materials-enabled efficient photothermal cancer therapy

(2016) Yu Chen et al.   Nano Today

Emerging understanding of the protein corona at the nano-bio interfaces

(2016) Morteza Mahmoudi et al.   Nano Today

Recent Advances in Synthesis and Biomedical Applications of Two-Dimensional Transition Metal Dichalcogenide Nanosheets

(2016) Xiao Li et al.   Small

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Exploration of graphene oxide as an intelligent platform for cancer vaccines

(2015) Hua Yue et al.   Nanoscale

Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG

(2014) Shiyu Yan et al.   BIOMATERIALS

Immunostimulatory oligonucleotides-loaded cationic graphene oxide with photothermally enhanced immunogenicity for photothermal/immune cancer therapy

(2014) Yu Tao et al.   BIOMATERIALS

Nanoscale Metal–Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer

(2014) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Two-Dimensional Nanocrystals Produced by Exfoliation of Ti3AlC2

(2011) Michael Naguib et al.   ADVANCED MATERIALS

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE