MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
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Title
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
Authors
Keywords
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Journal
EMBO Molecular Medicine
Volume 4, Issue 3, Pages 143-159
Publisher
EMBO
Online
2012-02-21
DOI
10.1002/emmm.201100209
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Note: Only part of the references are listed.- MicroRNA Sequence and Expression Analysis in Breast Tumors by Deep Sequencing
- (2011) T. A. Farazi et al. CANCER RESEARCH
- A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
- (2011) Leonardo Salmena et al. CELL
- MicroRNAs as regulators of epithelial-mesenchymal transition
- (2011) Philip A. Gregory et al. CELL CYCLE
- Overexpression of Dicer predicts poor survival in colorectal cancer
- (2011) C. Faber et al. EUROPEAN JOURNAL OF CANCER
- The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma
- (2011) Xiaofang Guo et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles
- (2011) Balaji Muralidhar et al. JOURNAL OF PATHOLOGY
- Functional relevance of miRNA* sequences in human disease
- (2011) Mihir K. Bhayani et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Silencing microRNA by interfering nanoparticles in mice
- (2011) Jie Su et al. NUCLEIC ACIDS RESEARCH
- MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer
- (2011) Mattia Boeri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
- (2010) S. Rossi et al. BLOOD
- Hunting for robust gene signature from cancer profiling data: Sources of variability, different interpretations, and recent methodological developments
- (2010) Jian-zhen Xu et al. CANCER LETTERS
- microRNA Signature and Expression of Dicer and Drosha Can Predict Prognosis and Delineate Risk Groups in Neuroblastoma
- (2010) R.-J. Lin et al. CANCER RESEARCH
- MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity
- (2010) Elisa Giovannetti et al. CANCER RESEARCH
- MicroRNAs: From Decay to Decoy
- (2010) Michaela Beitzinger et al. CELL
- Transcriptional Control of Gene Expression by MicroRNAs
- (2010) Basel Khraiwesh et al. CELL
- A MicroRNA Targeting Dicer for Metastasis Control
- (2010) Graziano Martello et al. CELL
- Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
- (2010) Susana Gonzalez et al. CELL CYCLE
- Thelet-7microRNA reduces tumor growth in mouse models of lung cancer
- (2010) Aurora Esquela-Kerscher et al. CELL CYCLE
- MicroRNA-21 Is Induced Early in Pancreatic Ductal Adenocarcinoma Precursor Lesions
- (2010) M. C. du Rieu et al. CLINICAL CHEMISTRY
- Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
- (2010) Lei Yu et al. INTERNATIONAL JOURNAL OF CANCER
- MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression
- (2010) Ming Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB
- (2010) Justin L. Mott et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- MicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma
- (2010) Stefano Caramuta et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers
- (2010) Lingxiao Xing et al. MODERN PATHOLOGY
- Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy
- (2010) Yunching Chen et al. MOLECULAR THERAPY
- OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
- (2010) Pedro P. Medina et al. NATURE
- Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
- (2010) Li Ma et al. NATURE BIOTECHNOLOGY
- Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment
- (2010) Mariàngels de Planell-Saguer et al. Nature Protocols
- starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
- (2010) Jian-Hua Yang et al. NUCLEIC ACIDS RESEARCH
- Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
- (2010) Johannes H. Schulte et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
- (2010) X Rao et al. ONCOGENE
- Systemic miRNA-195 Differentiates Breast Cancer from Other Malignancies and Is a Potential Biomarker for Detecting Noninvasive and Early Stage Disease
- (2010) H. M. Heneghan et al. ONCOLOGIST
- Inhibition of c-FLIP expression by miR-512-3p contributes to Taxol-induced apoptosis in hepatocellular carcinoma cells
- (2010) Chen ONCOLOGY REPORTS
- miR-24 Regulates Apoptosis by Targeting the Open Reading Frame (ORF) Region of FAF1 in Cancer Cells
- (2010) Wenming Qin et al. PLoS One
- Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame
- (2010) F. Moretti et al. RNA
- In situ detection of mature microRNAs by labeled extension on ultramer templates
- (2009) Gerard J. Nuovo et al. BIOTECHNIQUES
- MicroRNA 29b functions in acute myeloid leukemia
- (2009) R. Garzon et al. BLOOD
- Expression profiling of microRNAs by deep sequencing
- (2009) C. J. Creighton et al. BRIEFINGS IN BIOINFORMATICS
- Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype
- (2009) G Grelier et al. BRITISH JOURNAL OF CANCER
- microRNA-205 Regulates HER3 in Human Breast Cancer
- (2009) M. V. Iorio et al. CANCER RESEARCH
- miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase C
- (2009) P. Gandellini et al. CANCER RESEARCH
- Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
- (2009) Janaiah Kota et al. CELL
- Suppression of cell growth and invasion by miR-205 in breast cancer
- (2009) Hailong Wu et al. CELL RESEARCH
- Salivary microRNA: Discovery, Characterization, and Clinical Utility for Oral Cancer Detection
- (2009) N. J. Park et al. CLINICAL CANCER RESEARCH
- Progress and prospects: immune responses to viral vectors
- (2009) S Nayak et al. GENE THERAPY
- Essential and overlapping functions for mammalian Argonautes in microRNA silencing
- (2009) H. Su et al. GENES & DEVELOPMENT
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- (2009) M. S. Kumar et al. GENES & DEVELOPMENT
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- (2009) P. Mu et al. GENES & DEVELOPMENT
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- (2009) Danit Lebanony et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2009) Ashish Lal et al. MOLECULAR CELL
- miRNA in situ hybridization in formaldehyde and EDC–fixed tissues
- (2009) John T G Pena et al. NATURE METHODS
- Causes and consequences of microRNA dysregulation in cancer
- (2009) Carlo M. Croce NATURE REVIEWS GENETICS
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- (2009) Junfang Ji et al. NEW ENGLAND JOURNAL OF MEDICINE
- miRGen 2.0: a database of microRNA genomic information and regulation
- (2009) Panagiotis Alexiou et al. NUCLEIC ACIDS RESEARCH
- DIANA-microT web server: elucidating microRNA functions through target prediction
- (2009) M. Maragkakis et al. NUCLEIC ACIDS RESEARCH
- Labeled microRNA pull-down assay system: an experimental approach for high-throughput identification of microRNA-target mRNAs
- (2009) Ren-Jun Hsu et al. NUCLEIC ACIDS RESEARCH
- deepBase: a database for deeply annotating and mining deep sequencing data
- (2009) Jian-Hua Yang et al. NUCLEIC ACIDS RESEARCH
- Exosomes from human saliva as a source of microRNA biomarkers
- (2009) A Michael et al. ORAL DISEASES
- Repertoire of microRNAs in Epithelial Ovarian Cancer as Determined by Next Generation Sequencing of Small RNA cDNA Libraries
- (2009) Stacia K. Wyman et al. PLoS One
- Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
- (2009) T.-C. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer
- (2009) Merle Hanke et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
- (2008) R. Garzon et al. BLOOD
- CoGemiR: A comparative genomics microRNA database
- (2008) Vincenza Maselli et al. BMC GENOMICS
- Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
- (2008) Charles H. Lawrie et al. BRITISH JOURNAL OF HAEMATOLOGY
- miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
- (2008) Na Li et al. CANCER LETTERS
- Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
- (2008) M. Toyota et al. CANCER RESEARCH
- Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters
- (2008) Andrea Ventura et al. CELL
- MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
- (2008) Shuomin Zhu et al. CELL RESEARCH
- Hypoxia induces microRNA miR-210 in vitro and in vivo
- (2008) Kati Pulkkinen et al. FEBS LETTERS
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
- (2008) Douglas D. Taylor et al. GYNECOLOGIC ONCOLOGY
- miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
- (2008) Lin Xia et al. INTERNATIONAL JOURNAL OF CANCER
- MicroRNA Expression Profiles Associated With Prognosis and Therapeutic Outcome in Colon Adenocarcinoma
- (2008) Aaron J. Schetter et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer
- (2008) Jian-Jun Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1
- (2008) Tyler E. Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Raising the Profile of Cancer of Unknown Primary
- (2008) Karin A. Oien et al. JOURNAL OF CLINICAL ONCOLOGY
- MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of Survival
- (2008) Mary Dillhoff et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
- (2008) O. Kovalchuk et al. MOLECULAR CANCER THERAPEUTICS
- MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
- (2008) Ulf Andersson Ørom et al. MOLECULAR CELL
- Endogenous human microRNAs that suppress breast cancer metastasis
- (2008) Sohail F. Tavazoie et al. NATURE
- LNA-mediated microRNA silencing in non-human primates
- (2008) Joacim Elmén et al. NATURE
- MicroRNAs accurately identify cancer tissue origin
- (2008) Nitzan Rosenfeld et al. NATURE BIOTECHNOLOGY
- Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
- (2008) Changchun Xiao et al. NATURE IMMUNOLOGY
- Stable knockdown of microRNA in vivo by lentiviral vectors
- (2008) Bernhard Gentner et al. NATURE METHODS
- Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
- (2008) Witold Filipowicz et al. NATURE REVIEWS GENETICS
- MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
- (2008) Lasse Sinkkonen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
- (2008) Roberta Benetti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer
- (2008) William M. Merritt et al. NEW ENGLAND JOURNAL OF MEDICINE
- miRecords: an integrated resource for microRNA-target interactions
- (2008) F. Xiao et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-directed transcriptional gene silencing in mammalian cells
- (2008) D. H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MiR-15a and miR-16-1 cluster functions in human leukemia
- (2008) George A. Calin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circulating microRNAs as stable blood-based markers for cancer detection
- (2008) P. S. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues
- (2008) H. J. Peltier et al. RNA
- Selective Blockade of MicroRNA Processing by Lin28
- (2008) S. R. Viswanathan et al. SCIENCE
- Widespread Translational Inhibition by Plant miRNAs and siRNAs
- (2008) P. Brodersen et al. SCIENCE
- Epigenetic inactivation of microRNA genehsa-mir-9-1in human breast cancer
- (2007) U Lehmann et al. JOURNAL OF PATHOLOGY
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