Stat3 loss in mesenchymal progenitors causes Job syndrome–like skeletal defects by reducing Wnt/β-catenin signaling

Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin

(2020) Taifeng Zhou et al.   eLife

An atlas of dynamic chromatin landscapes in mouse fetal development

(2020) David U. Gorkin et al.   NATURE

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

(2019) Phillip T. Newton et al.   NATURE

A Novel STAT3 Mutation in a Qatari Patient With Hyper-IgE Syndrome

(2019) Natalia S. Chaimowitz et al.   Frontiers in Pediatrics

A new background subtraction method for Western blot densitometry band quantification through image analysis software

(2018) Gabriel Gallo-Oller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression

(2018) Yusuke Mochizuki et al.   DEVELOPMENTAL CELL

TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes

(2018) Nikolaos Doumpas et al.   EMBO JOURNAL

InducedGnasR201Hexpression from the endogenousGnaslocus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling

(2017) Sanjoy Kumar Khan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes

(2017) Michael D. Hall et al.   PLoS Genetics

Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation

(2017) Yinzi Liu et al.   PLoS Genetics

Loss of stat3 function leads to spine malformation and immune disorder in zebrafish

(2017) Shuting Xiong et al.   Science Bulletin

Signal transducer and activator of transcription 3

(2016) Lisa R. Forbes et al.   CURRENT OPINION IN HEMATOLOGY

STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells

(2016) Minkyung Shin et al.   MOLECULES AND CELLS

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation

(2016) Jianqiang Wu et al.   Cell Reports

High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

(2015) Paul J Niziolek et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity

(2015) Claudia Mertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

(2014) J. D. Milner et al.   BLOOD

Cell competition: how to eliminate your neighbours

(2014) M. Amoyel et al.   DEVELOPMENT

Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones

(2014) Paritosh Prashar et al.   DEVELOPMENTAL BIOLOGY

STAT3 paradoxically stimulates β-catenin expression but inhibits β-catenin function

(2014) Salih Ibrahem et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

(2014) Sarah E Flanagan et al.   NATURE GENETICS

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoclasts: more than ‘bone eaters’

(2014) Julia F. Charles et al.   TRENDS IN MOLECULAR MEDICINE

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

(2014) Xin Zhou et al.   PLoS Genetics

Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor

(2013) Graziano Martello et al.   EMBO JOURNAL

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

(2013) Jean B Regard et al.   NATURE MEDICINE

DAVID-WS: a stateful web service to facilitate gene/protein list analysis

(2012) X. Jiao et al.   BIOINFORMATICS

Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes

(2012) Peter Dy et al.   DEVELOPMENTAL CELL

The Wnt/β-Catenin Pathway Cross-Talks with STAT3 Signaling to Regulate Survival of Retinal Pigment Epithelium Cells

(2012) Miryam A. Fragoso et al.   PLoS One

Osteoblast/osteocyte-specific inactivation of Stat3 decreases load-driven bone formation and accumulates reactive oxygen species

(2011) Hongkang Zhou et al.   BONE

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells

(2011) L. Lin et al.   CANCER RESEARCH

Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization

(2011) Ingrid J Poulton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Lrp5 functions in bone to regulate bone mass

(2011) Yajun Cui et al.   NATURE MEDICINE

Pharmaceutical inhibition of glycogen synthetase kinase-3  reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model

(2010) W. G. Gunn et al.   BLOOD

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome

(2010) Cristina Woellner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling

(2008) Peter ten Dijke et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME