Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes

The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers

(2015) B. Yao et al.   NUCLEIC ACIDS RESEARCH

Contribution of the Interleukin-6/STAT-3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells

(2015) Masahiro Kondo et al.   Arthritis & Rheumatology

Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

(2015) Shunsuke Tanigawa et al.   Stem Cell Reports

Fibroblast Growth Factor Maintains Chondrogenic Potential of Limb Bud Mesenchymal Cells by Modulating DNMT3A Recruitment

(2014) Deepak Kumar et al.   Cell Reports

Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions

(2013) Andrew Paul Hutchins et al.   NUCLEIC ACIDS RESEARCH

A far-upstream (−70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration

(2013) Timothy J. Mead et al.   NUCLEIC ACIDS RESEARCH

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

(2013) M R Pawlus et al.   ONCOGENE

STAT3 or USF2 Contributes to HIF Target Gene Specificity

(2013) Matthew R. Pawlus et al.   PLoS One

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

(2012) Janel L. Kopp et al.   CANCER CELL

Oncogenicity of the Developmental Transcription Factor Sox9

(2012) A. Matheu et al.   CANCER RESEARCH

Leukemia inhibitory factor: A paracrine mediator of bone metabolism

(2012) Natalie A. Sims et al.   GROWTH FACTORS

The postnatal role of Sox9 in cartilage

(2012) Stephen P Henry et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoblast/osteocyte-specific inactivation of Stat3 decreases load-driven bone formation and accumulates reactive oxygen species

(2011) Hongkang Zhou et al.   BONE

Muscle force regulates bone shaping for optimal load-bearing capacity during embryogenesis

(2011) A. Sharir et al.   DEVELOPMENT

SOX9 controls epithelial branching by activating RET effector genes during kidney development

(2011) Antoine Reginensi et al.   HUMAN MOLECULAR GENETICS

Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization

(2011) Ingrid J Poulton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome–like skeletal defects induced by Pdk1 or Cbp mutations in mice

(2011) Jae-Hyuck Shim et al.   JOURNAL OF CLINICAL INVESTIGATION

Signal Transducers and Activators of Transcription-3 Binding to the Fibroblast Growth Factor Receptor Is Activated by Receptor Amplification

(2010) A. A. Dudka et al.   CANCER RESEARCH

Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo

(2010) Jacqueline D. Peacock et al.   CIRCULATION RESEARCH

Stat3 is essential for neuronal differentiation through direct transcriptional regulation of the Sox6 gene

(2010) Marylynn Snyder et al.   FEBS LETTERS

Long-range regulation at the SOX9 locus in development and disease

(2009) C T Gordon et al.   JOURNAL OF MEDICAL GENETICS

Regulation of Sox2 by STAT3 Initiates Commitment to the Neural Precursor Cell Fate

(2008) Kara M. Foshay et al.   STEM CELLS AND DEVELOPMENT