Uncovering the mechanism of the Shenzhi Jiannao formula against vascular dementia using a combined network pharmacology approach and molecular biology

RNA sequencing analysis of monocrotaline-induced PAH reveals dysregulated chemokine and neuroactive ligand receptor pathways

(2020) Genfa Xiao et al.   Aging-US

Protection against acute cerebral ischemia/reperfusion injury by QiShenYiQi via neuroinflammatory network mobilization

(2020) Yule Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease

(2020) Shi-Yu Chen et al.   Frontiers in Pharmacology

The Role of NMDA Receptors in Alzheimer’s Disease

(2019) Jinping Liu et al.   Frontiers in Neuroscience

Ginsenoside compound K attenuates cognitive deficits in vascular dementia rats by reducing the Aβ deposition

(2019) Wenjing Zong et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Naomaitai Ameliorated Brain Damage in Rats with Vascular Dementia by PI3K/PDK1/AKT Signaling Pathway

(2019) Kui Huang et al.   Evidence-based Complementary and Alternative Medicine

Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies

(2019) Ying-Jui Ho et al.   Frontiers in Neuroscience

Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment

(2019) Tamas Kiss et al.   GeroScience

Integrating Pharmacokinetics Study, Network Analysis, and Experimental Validation to Uncover the Mechanism of Qiliqiangxin Capsule Against Chronic Heart Failure

(2019) Yu Zhang et al.   Frontiers in Pharmacology

A combined molecular biology and network pharmacology approach to investigate the multi-target mechanisms of Chaihu Shugan San on Alzheimer’s disease

(2019) Qiang Zeng et al.   BIOMEDICINE & PHARMACOTHERAPY

Autodock Vina Adopts More Accurate Binding Poses but Autodock4 Forms Better Binding Affinity

(2019) Nguyen Thanh Nguyen et al.   Journal of Chemical Information and Modeling

Endothelial Cell Autonomous Role of Akt1Highlights

(2018) Monica Y. Lee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia

(2018) Xin Jiang et al.   BEHAVIOURAL BRAIN RESEARCH

Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options

(2018) Emine Sekerdag et al.   Current Neuropharmacology

Evaluation of AutoDock and AutoDock Vina on the CASF-2013 benchmark

(2018) Thomas Gaillard   Journal of Chemical Information and Modeling

Panax ginseng extract attenuates neuronal injury and cognitive deficits in rats with vascular dementia induced by chronic cerebral hypoperfusion

(2018) Jun-De Zhu et al.   Neural Regeneration Research

Aerobic exercise upregulates the BDNF-Serotonin systems and improves the cognitive function in rats

(2018) A. Pietrelli et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Dysfunctional Pro-Ceramide, ER Stress, and Insulin/IGF Signaling Networks with Progression of Alzheimer's Disease

(2018) Suzanne M. de la Monte et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature

(2018) Katherine McEvoy et al.   Current Psychiatry Reports

Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta-analysis

(2018) Ze-Yu Zhang et al.   BMC Complementary and Alternative Medicine

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

Role of Glutamate and NMDA Receptors in Alzheimer’s Disease

(2017) Rui Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Comprehensive profiling and characterization of chemical constituents of rhizome of Anemarrhena asphodeloides Bge.

(2017) De Ji et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Etidronate rescues cognitive deficits through improving synaptic transmission and suppressing apoptosis in 2-vessel occlusion model rats

(2017) Wen Li et al.   JOURNAL OF NEUROCHEMISTRY

Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury

(2017) Christopher R. Dorsett et al.   JOURNAL OF NEUROTRAUMA

Pathogenic mechanisms following ischemic stroke

(2017) Seyed Esmaeil Khoshnam et al.   NEUROLOGICAL SCIENCES

The PI3K/Akt pathway: a critical player in intervertebral disc degeneration

(2017) Zhi-Hua Ouyang et al.   Oncotarget

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

(2016) Raj N. Kalaria   ACTA NEUROPATHOLOGICA

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Major pathogenic mechanisms in vascular dementia: Roles of cellular stress response and hormesis in neuroprotection

(2016) Vittorio Calabrese et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Methamphetamine-induced dopaminergic toxicity prevented owing to the neuroprotective effects of salicylic acid

(2016) Bessy Thrash-Williams et al.   LIFE SCIENCES

Recent Knowledge on Medicinal Plants as Source of Cholinesterase Inhibitors for the Treatment of Dementia

(2016) Rosa Tundis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity

(2016) Sebastian P Fernandez et al.   NEUROPSYCHOPHARMACOLOGY

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

(2016) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Improving chemical similarity ensemble approach in target prediction

(2016) Zhonghua Wang et al.   Journal of Cheminformatics

BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine

(2016) Zhongyang Liu et al.   Scientific Reports

Protective effects of ginsenoside Rg1 on intestinal ischemia/reperfusion injury-induced oxidative stress and apoptosis via activation of the Wnt/β-catenin pathway

(2016) Guo Zu et al.   Scientific Reports

Insulin resistance predicts brain amyloid deposition in late middle-aged adults

(2015) Auriel A. Willette et al.   Alzheimers & Dementia

Atorvastatin attenuates cognitive deficits through Akt1/caspase-3 signaling pathway in ischemic stroke

(2015) Jie Yang et al.   BRAIN RESEARCH

Psychiatric and cognitive symptoms in Huntington's disease are modified by polymorphisms in catecholamine regulating enzyme genes

(2015) T. Vinther-Jensen et al.   CLINICAL GENETICS

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

SwissTargetPrediction: a web server for target prediction of bioactive small molecules

(2014) David Gfeller et al.   NUCLEIC ACIDS RESEARCH

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Nonautonomous Regulation of Neuronal Migration by Insulin Signaling, DAF-16/FOXO, and PAK-1

(2013) Lisa M. Kennedy et al.   Cell Reports

Incidence and Subtypes of MCI and Dementia 1 Year after First-Ever Stroke in Patients without Pre-Existing Cognitive Impairment

(2012) Hege Ihle-Hansen et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Prevalence of Poststroke Cognitive Impairment

(2012) Abdel Douiri et al.   STROKE

Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implications

(2011) Deborah A. Levine et al.   Neurotherapeutics

Transcriptomic analysis of EGb 761-regulated neuroactive receptor pathway in vivo

(2009) Shan-Yu Su et al.   JOURNAL OF ETHNOPHARMACOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols