FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling

Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells

(2014) Xiaoli Ju et al.   CANCER SCIENCE

Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

(2014) Junyan Tao et al.   GASTROENTEROLOGY

Regulation of PCP by the Fat signaling pathway

(2013) M. Matis et al.   GENES & DEVELOPMENT

Sleeping Giants: Emerging Roles for the Fat Cadherins in Health and Disease

(2013) Elham Sadeqzadeh et al.   MEDICINAL RESEARCH REVIEWS

Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation

(2013) Amrita Das et al.   NATURE CELL BIOLOGY

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

(2013) Luc G T Morris et al.   NATURE GENETICS

An evolutionary shift in the regulation of the Hippo pathway between mice and flies

(2013) W Bossuyt et al.   ONCOGENE

Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer

(2012) S. Lee et al.   CANCER RESEARCH

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity

(2012) S. Saburi et al.   DEVELOPMENT

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

(2012) Masamichi Imajo et al.   EMBO JOURNAL

The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer

(2012) Marcello Ferretti Fanelli et al.   HISTOPATHOLOGY

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

(2012) Zhi Jiang Zang et al.   NATURE GENETICS

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

(2011) Y. Mao et al.   DEVELOPMENT

Targeting the Wnt/β-catenin signaling pathway in human cancers

(2011) Hisayuki Yao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis–relapse samples of precursor B-cell acute lymphoblastic leukemia

(2011) C E de Bock et al.   LEUKEMIA

DNA methylation biomarkers for lung cancer

(2011) Tibor A. Rauch et al.   TUMOR BIOLOGY

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Gastric cancer

(2009) Vincenzo Catalano et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Atrophin Proteins Interact with the Fat1 Cadherin and Regulate Migration and Orientation in Vascular Smooth Muscle Cells

(2009) Rong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex

(2009) Takashi Ishiuchi et al.   JOURNAL OF CELL BIOLOGY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Does vimentin help to delineate the so-called 'basal type breast cancer'?

(2009) Renata U Kusinska et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

(2009) K. Skouloudaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of Members of the Cadherin Superfamily in Cancer

(2009) G. Berx et al.   Cold Spring Harbor Perspectives in Biology

Membrane-type 1 matrix metalloproteinase regulates cell migration during zebrafish gastrulation: Evidence for an interaction with non-canonical Wnt signaling

(2008) Rebecca C. Coyle et al.   EXPERIMENTAL CELL RESEARCH

Molecular evolution of the cadherin superfamily

(2008) Paco Hulpiau et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Identification of Fat4 as a candidate tumor suppressor gene in breast cancers

(2008) Chao Qi et al.   INTERNATIONAL JOURNAL OF CANCER