Targeting the Wnt/β-catenin signaling pathway in human cancers

Targeting Wnt Signaling in Colon Cancer Stem Cells

(2010) E. M. F. de Sousa et al.   CLINICAL CANCER RESEARCH

Future Prospect of RNA Interference for Cancer Therapies

(2010) Eishi Ashihara et al.   CURRENT DRUG TARGETS

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Transcriptional inactivation of secreted frizzled-related protein 1 by promoter hypermethylation as a potential biomarker for non-small cell lung cancer

(2010) Y. Zhang et al.   NEOPLASMA

Prognostic relevance ofβ-cateninexpression in T2-3N0M0 esophageal squamous cell carcinoma

(2010) Dong-Rong Situ   WORLD JOURNAL OF GASTROENTEROLOGY

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

Isoreserpine promotes β-catenin degradation via Siah-1 up-regulation in HCT116 colon cancer cells

(2009) Jungsug Gwak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

(2009) Otto Schmalhofer et al.   CANCER AND METASTASIS REVIEWS

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

 -Catenin Small Interfering RNA Successfully Suppressed Progression of Multiple Myeloma in a Mouse Model

(2009) E. Ashihara et al.   CLINICAL CANCER RESEARCH

Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells

(2009) Wei Wei et al.   Molecular Cancer

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Imatinib and beyond—exploring the full potential of targeted therapy for CML

(2009) Alfonso Quintás-Cardama et al.   Nature Reviews Clinical Oncology

Overexpression of Wnt-2 in colorectal cancers

(2009) J. Park et al.   NEOPLASMA

Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma

(2009) G Akiri et al.   ONCOGENE

Wnt signaling: the good and the bad

(2008) Xi Chen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

(2008) H Suzuki et al.   BRITISH JOURNAL OF CANCER

Promoter methylation of the Wnt/β-catenin signaling antagonistDkk-3is associated with poor survival in gastric cancer

(2008) Jun Yu et al.   CANCER

Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

(2008) J. B. Tuynman et al.   CANCER RESEARCH

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

(2008) T. T. Onder et al.   CANCER RESEARCH

Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling

(2008) Ilaria Malanchi et al.   NATURE

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

(2008) D. Peer et al.   SCIENCE

Nuclear β-catenin expression as a prognostic factor in advanced colorectal carcinoma

(2008) Adam Elzagheid et al.   WORLD JOURNAL OF GASTROENTEROLOGY