Precision medicine approaches for diabetic kidney disease: opportunities and challenges

Prediction and validation of exenatide risk marker effects on progression of renal disease: Insights from EXSCEL

(2020) Nienke M.A. Idzerda et al.   DIABETES OBESITY & METABOLISM

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Boris Bikbov et al.   LANCET

Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial

(2020) Nete Tofte et al.   Lancet Diabetes & Endocrinology

Genome-Wide Association Studies of CKD and Related Traits

(2020) Adrienne Tin et al.   Clinical Journal of the American Society of Nephrology

Treatment Options for MODY Patients: A Systematic Review of Literature

(2020) Maurizio Delvecchio et al.   Diabetes Therapy

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials

(2019) Hiddo J L Heerspink et al.   Lancet Diabetes & Endocrinology

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

(2019) Hiddo J L Heerspink et al.   LANCET

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes

(2019) Monika A. Niewczas et al.   NATURE MEDICINE

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

A catalog of genetic loci associated with kidney function from analyses of a million individuals

(2019) Matthias Wuttke et al.   NATURE GENETICS

Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data

(2019) John M Dennis et al.   Lancet Diabetes & Endocrinology

Genetic and Epigenetic Studies in Diabetic Kidney Disease

(2019) Harvest F. Gu   Frontiers in Genetics

Emerging urine-based proteomic biomarkers as valuable tools in the management of chronic kidney disease

(2019) Petra Zürbig et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

(2019) Rany M. Salem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2020

(2019)   DIABETES CARE

Distinguishing prognostic and predictive biomarkers: an information theoretic approach

(2018) Konstantinos Sechidis et al.   BIOINFORMATICS

Neonatal Diabetes Mellitus

(2018) Michelle Blanco Lemelman et al.   CLINICS IN PERINATOLOGY

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

(2018) Natalie R. van Zuydam et al.   DIABETES

NT-proBNP predicts the cardio-renal response to aliskiren in patients with type 2 diabetes at high renal and cardiovascular risk

(2018) Nienke M.A. Idzerda et al.   DIABETES OBESITY & METABOLISM

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

(2018) Emma Ahlqvist et al.   Lancet Diabetes & Endocrinology

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

ISPAD 2018 Consensus Guidelines: The diagnosis and management of monogenic diabetes in children and adolescents

(2018) Andrew T. Hattersley et al.   PEDIATRIC DIABETES

Precision Transplant Medicine: Biomarkers to the Rescue

(2017) Maarten Naesens et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasma Biomarkers and Kidney Function Decline in Early and Established Diabetic Kidney Disease

(2017) Steven G. Coca et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus

(2016) Hiddo J.L. Heerspink et al.   CIRCULATION

Recognition and Management of Individuals With Hyperglycemia Because of a Heterozygous Glucokinase Mutation

(2015) Ali J. Chakera et al.   DIABETES CARE

Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers

(2015) Bauke Schievink et al.   European Journal of Preventive Cardiology

Epidemiology and Risk Factors for Diabetic Kidney Disease

(2014) Valma Harjutsalo et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

The Endothelin Antagonist Atrasentan Lowers Residual Albuminuria in Patients with Type 2 Diabetic Nephropathy

(2014) D. de Zeeuw et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Diabetic nephropathy—emerging epigenetic mechanisms

(2014) Mitsuo Kato et al.   Nature Reviews Nephrology

Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy

(2014) Justyna Siwy et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Importance of Short-Term Off-Target Effects in Estimating the Long-Term Renal and Cardiovascular Protection of Angiotensin Receptor Blockers

(2013) P A Smink et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Ethnicity and long-term vascular outcomes in Type 2 diabetes: a prospective observational study (UKPDS 83)

(2013) T. M. E. Davis et al.   DIABETIC MEDICINE

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

(2013) Ron T Gansevoort et al.   LANCET

A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus

(2012) S. S. Roscioni et al.   DIABETOLOGIA

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

Confirmation of Genetic Associations at ELMO1 in the GoKinD Collection Supports Its Role as a Susceptibility Gene in Diabetic Nephropathy

(2009) M. G. Pezzolesi et al.   DIABETES

Risk Factors for Development and Progression of Diabetic Kidney Disease and Treatment Patterns Among Diabetic Siblings of Patients With Diabetic Kidney Disease

(2008) Anthony J. Bleyer et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Monogenic Diabetes in the Young, Pharmacogenetics and Relevance to Multifactorial Forms of Type 2 Diabetes

(2008) Martine Vaxillaire et al.   ENDOCRINE REVIEWS

ACE Gene Polymorphism and Losartan Treatment in Type 2 Diabetic Patients With Nephropathy

(2008) H.-H. Parving et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY