Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription

The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning

(2021) Eric J. Tomko et al.   JOURNAL OF MOLECULAR BIOLOGY

A high-resolution protein architecture of the budding yeast genome

(2021) Matthew J. Rossi et al.   NATURE

Structure of the human Mediator-bound transcription preinitiation complex

(2021) R. Abdella et al.   SCIENCE

Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core

(2021) Haiyan Zhao et al.   Nature Communications

Structures of mammalian RNA polymerase II pre-initiation complexes

(2021) Shintaro Aibara et al.   NATURE

Structure of the human Mediator–RNA polymerase II pre-initiation complex

(2021) Srinivasan Rengachari et al.   NATURE

Structural insights into preinitiation complex assembly on core promoters

(2021) Xizi Chen et al.   SCIENCE

Structures of the human Mediator and Mediator-bound preinitiation complex

(2021) Xizi Chen et al.   SCIENCE

Transcription in Living Cells: Molecular Mechanisms of Bursting

(2020) Joseph Rodriguez et al.   Annual Review of Biochemistry

Structure and mechanism of the RNA polymerase II transcription machinery

(2020) Allison C. Schier et al.   GENES & DEVELOPMENT

Biomolecular Condensates in the Nucleus

(2020) Benjamin R. Sabari et al.   TRENDS IN BIOCHEMICAL SCIENCES

Unexpected specificity within dynamic transcriptional protein–protein complexes

(2020) Matthew J. Henley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complete structure of the human TFIIH core complex

(2019) Basil J Greber et al.   eLife

50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms

(2019) Robert G. Roeder   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

(2018) Avinash B. Patel et al.   SCIENCE

Structures of transcription pre-initiation complex with TFIIH and Mediator

(2017) S. Schilbach et al.   NATURE

Mediator structure and rearrangements required for holoenzyme formation

(2017) Kuang-Lei Tsai et al.   NATURE

Paused RNA polymerase II inhibits new transcriptional initiation

(2017) Wanqing Shao et al.   NATURE GENETICS

CDK9-dependent RNA polymerase II pausing controls transcription initiation

(2017) Saskia Gressel et al.   eLife

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

(2016) Philip J. Robinson et al.   CELL

A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

(2016) Katjana Tantale et al.   Nature Communications

Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation

(2015) James Fishburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

(2011) Hidehisa Takahashi et al.   CELL