Structural basis of ketamine action on human NMDA receptors

Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors

(2021) Gary J. Iacobucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational spread and dynamics in allostery of NMDA receptors

(2020) Ryan J. Durham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1

(2020) Jasenko Zivanov et al.   IUCrJ

Structural Basis of Functional Transitions in Mammalian NMDA Receptors

(2020) Tsung-Han Chou et al.   CELL

Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function

(2019) Eric W. Lumsden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine

(2019) Lijia Chang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

(2018) Samuel T. Wilkinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Mechanism of NMDA receptor channel block by MK-801 and memantine

(2018) Xianqiang Song et al.   NATURE

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

(2018) Yan Yang et al.   NATURE

Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor

(2018) Farzad Jalali-Yazdi et al.   CELL

Depression

(2018) Gin S Malhi et al.   LANCET

Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

(2018) Maurizio Fava et al.   MOLECULAR PSYCHIATRY

Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors

(2018) Jin-Bao Zhang et al.   Cell Reports

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation

(2017) Wei Lü et al.   SCIENCE

Mechanism of NMDA Receptor Inhibition and Activation

(2016) Shujia Zhu et al.   CELL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis of kainate subtype glutamate receptor desensitization

(2016) Joel R. Meyerson et al.   NATURE

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

(2016) Ronald S Duman et al.   NATURE MEDICINE

New tools for structure refinement inPHENIX

(2015) Paul Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION A

g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations

(2014) Rashmi Kumari et al.   Journal of Chemical Information and Modeling

NMDA receptor structures reveal subunit arrangement and pore architecture

(2014) Chia-Hsueh Lee et al.   NATURE

Crystal structure of a heterotetrameric NMDA receptor ion channel

(2014) E. Karakas et al.   SCIENCE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing

(2012) K. Vanommeslaeghe et al.   Journal of Chemical Information and Modeling

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY