Lymph-Node-Targeted Cholesterolized TLR7 Agonist Liposomes Provoke a Safe and Durable Antitumor Response

Cancer immunotherapy: Pros, cons and beyond

(2020) Shuzhen Tan et al.   BIOMEDICINE & PHARMACOTHERAPY

Lymph node-targeted immune-activation mediated by imiquimod-loaded mesoporous polydopamine based-nanocarriers

(2020) Lu Wang et al.   BIOMATERIALS

Visualizing DC morphology and T cell motility to characterize DC-T cell encounters in mouse lymph nodes under mTOR inhibition

(2019) Qiaoya Lin et al.   Science China-Life Sciences

DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node

(2019) Caterina Curato et al.   Frontiers in Immunology

Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

(2018) Liangliang Dai et al.   ADVANCED FUNCTIONAL MATERIALS

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

(2018) Ethel R. Pereira et al.   SCIENCE

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

(2018) M. Brown et al.   SCIENCE

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

(2018) Melody Smith et al.   OncoImmunology

Mechanisms and Dynamics of T Cell-Mediated Cytotoxicity In Vivo

(2017) Stephan Halle et al.   TRENDS IN IMMUNOLOGY

Intratumoral Delivery of Immunotherapy—Act Locally, Think Globally

(2016) M. Angela Aznar et al.   JOURNAL OF IMMUNOLOGY

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

(2016) Lutz Nuhn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo

(2015) Elliot C. Woods et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants

(2015) Melissa C. Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL

(2013) Hwee Ying Lim et al.   Cell Metabolism

Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?

(2013) L. M. Coussens et al.   SCIENCE

Systemic delivery of a TLR7 agonist in combination with radiation primes durable antitumor immune responses in mouse models of lymphoma

(2012) S. J. Dovedi et al.   BLOOD

Immunology beats cancer: a blueprint for successful translation

(2012) Drew M Pardoll   NATURE IMMUNOLOGY

Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy

(2011) Haipeng Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles

(2011) C. M. Jewell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

(2011) C. Nembrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pharmacokinetics of Toll-like receptor agonists and the impact on the immune system

(2011) Abbi L Engel et al.   Expert Review of Clinical Pharmacology

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

(2008) S. Baenziger et al.   BLOOD

TLR7 and TLR8 as targets in cancer therapy

(2008) M P Schön et al.   ONCOGENE