Design, Synthesis and Anticancer Evaluation of Substituted Cinnamic Acid Bearing 2-Quinolone Hybrid Derivatives

Pentacyclic Triterpenoids with Nitrogen-Containing Heterocyclic Moiety, Privileged Hybrids in Anticancer Drug Discovery

(2021) Vuyolwethu Khwaza et al.   MOLECULES

Synthesis and cytotoxicity screening of some synthesized hybrid nitrogen molecules as anticancer agents

(2021) Ahmed A.E. Mourad et al.   JOURNAL OF MOLECULAR STRUCTURE

Arylidenes of Quinolin-2-one scaffold as Erlotinib analogues with activities against leukemia through inhibition of EGFR TK/ STAT-3 pathways

(2020) Mohammed A.I. Elbastawesy et al.   BIOORGANIC CHEMISTRY

Evaluation of the biological potential of ruthenium(II) complexes with cinnamic acid

(2020) Angelica E. Graminha et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tertiary phosphines in reactions with substituted cinnamic acids

(2020) Semyon Romanov et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Design and Synthesis of Molecular Hybrids of Sophora Alkaloids and Cinnamic Acids as Potential Antitumor Agents

(2020) Hai Shang et al.   MOLECULES

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

(2020) Shahad W. Kattan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Class-selective voltammetric determination of hydroxycinnamic acids structural analogs using a WS2/catechin-capped AuNPs/carbon black–based nanocomposite sensor

(2020) Flavio Della Pelle et al.   MICROCHIMICA ACTA

The indenoisoquinoline LMP517: a novel antitumor agent targeting both TOP1 and TOP2

(2020) Laetitia Marzi et al.   MOLECULAR CANCER THERAPEUTICS

Recent Advances of Cinnamic Acids in Organic Synthesis

(2020) Lihua Chen et al.   Asian Journal of Organic Chemistry

DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models

(2020) Hurng-Wern Huang et al.   Cancers

Design, synthesis, and cytotoxicity screening of new synthesized imidazolidine‐2‐thiones as VEGFR‐2 enzyme inhibitors

(2020) Islam Zaki et al.   ARCHIV DER PHARMAZIE

Cinnamic Acid Derivatives and Their Biological Efficacy

(2020) Ngonidzashe Ruwizhi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

(2020) Eman S. Tantawy et al.   JOURNAL OF MOLECULAR STRUCTURE

Natural Sources, Pharmacokinetics, Biological Activities and Health Benefits of Hydroxycinnamic Acids and Their Metabolites

(2020) Matej Sova et al.   Nutrients

Construction of cinnamic acids derived β-cyclodextrins and their emodin-based inclusions with enhanced water solubility, excellent antioxidant and antibacterial activities

(2020) Jing Zhang et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

(2020) Natassja G. Bush et al.   MOLECULES

Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies

(2019) Rajkumar Reddyrajula et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities

(2019) V. Raja Solomon et al.   Scientific Reports

Hydroxycinnamic acids and human health. Recent advances

(2019) Vasile Coman et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Exploration of quinolone and quinoline derivatives as potential anticancer agents

(2019) Jamshed Iqbal et al.   DARU-Journal of Pharmaceutical Sciences

Synthesis and evaluation of a novel quinoline-triazole analogs for antitubercular properties via molecular hybridization approach

(2019) Jurupula Ramprasad et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives

(2019) Ahmed I. Khodair et al.   CARBOHYDRATE RESEARCH

Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs

(2019) Ana Teresa Silva et al.   MOLECULES

Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents

(2019) Mohamed S. Nafie et al.   STEROIDS

An insight into the therapeutic potential of quinazoline derivatives as anticancer agents

(2017) Shagufta Shagufta et al.   MedChemComm

Small hybrid heteroaromatics: resourceful biological tools in cancer research

(2017) Vikrant Abbot et al.   RSC Advances

Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach

(2016) Bin Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, regioselective synthesis and cytotoxic evaluation of 2-aminoimidazole–quinoline hybrids against cancer and primary endothelial cells

(2014) Kuldeep Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Advances in the development of hybrid anticancer drugs

(2013) Sébastien Fortin et al.   Expert Opinion on Drug Discovery

Synthesis, cytotoxic evaluation, docking andin silicopharmacokinetic prediction of 4-arylideneamino/cycloalkylidineamino 1, 2-naphthoquinone thiosemicarbazones

(2012) Shubhanjali Shukla et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock

(2009) Zsolt Bikadi et al.   Journal of Cheminformatics