Design, synthesis, and cytotoxicity screening of new synthesized imidazolidine‐2‐thiones as VEGFR‐2 enzyme inhibitors

VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents

(2020) Eman Y. Ahmed et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In Vitro Antitumor Evaluation of Some Hybrid Molecules Containing Coumarin and Quinolinone Moieties

(2019) Youstina W. Rizzk et al.   Anti-Cancer Agents in Medicinal Chemistry

Design, synthesis and in vitro evaluation of 6-amide-2-aryl benzoxazole/benzimidazole derivatives against tumor cells by inhibiting VEGFR-2 kinase

(2019) Xu Yuan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of arylamide-5-anilinoquinazoline-8-nitro derivatives as VEGFR-2 kinase inhibitors: Synthesis, in vitro biological evaluation and molecular docking

(2019) Yongqiang Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The discovery of the fundamental role of VEGF in the development of the vascular system

(2019) Domenico Ribatti   MECHANISMS OF DEVELOPMENT

Novel pyrrol-2(3 H )-ones and pyridazin-3(2 H )-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors

(2018) Mahmoud S. Abdelbaset et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological evaluation of pyrimidine-based derivatives as VEGFR-2 tyrosine kinase inhibitors

(2018) Wuji Sun et al.   BIOORGANIC CHEMISTRY

Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7

(2018) Eman F. Abdelhaleem et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line

(2018) Islam Zaki et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors

(2018) Mohammed K. AbdElhameid et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies

(2018) Khaled O. Mohamed et al.   BIOORGANIC CHEMISTRY

Third-Generation Tyrosine Kinase Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer

(2017) Tristan A. Barnes et al.   Frontiers in Oncology

Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2

(2016) Anatolii R. Syniugin et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells

(2015) Santhalakshmi Ranganathan et al.   PLoS One

Targeted anticancer therapy: Overexpressed receptors and nanotechnology

(2014) Mohd Javed Akhtar et al.   CLINICA CHIMICA ACTA

Novel VEGFR-2 kinase inhibitors identified by the back-to-front approach

(2013) Kingkan Sanphanya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2)

(2013) Enrico Perspicace et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors

(2012) M. McTigue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer property of gallic acid in A549, a human lung adenocarcinoma cell line, and possible mechanisms

(2010) Dharmendra K. Maurya et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype

(2009) N. Almog et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor Receptor-2 Expression Is Down-Regulated by 17β-Estradiol in MCF-7 Breast Cancer Cells by Estrogen Receptor α/Sp Proteins

(2007) Kelly J. Higgins et al.   MOLECULAR ENDOCRINOLOGY