ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease

Title
ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease
Authors
Keywords
Machado-Joseph disease, Spinocerebellar Ataxia Type 3, ataxin-3, autophagy, transcriptional dysregulation, Unc-51 like autophagy activating kinase 1 and 2, adeno-associated viral vectors, gene therapy, neuroprotection, motor improvements
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-07-22
DOI
10.1016/j.ymthe.2021.07.012

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