Caffeine and adenosine A2Areceptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease

Caffeine, Adenosine Receptors, and Synaptic Plasticity

(2017) Ana Rita Costenla et al.   JOURNAL OF ALZHEIMERS DISEASE

Chronic Caffeine Consumption Prevents Memory Disturbance in Different Animal Models of Memory Decline

(2017) Rodrigo A. Cunha et al.   JOURNAL OF ALZHEIMERS DISEASE

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease

(2012) A. T. Simoes et al.   BRAIN

Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes

(2012) Marco Matos et al.   GLIA

Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice

(2012) João M. N. Duarte et al.   PLoS One

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction

(2011) Nelson Rebola et al.   JOURNAL OF NEUROCHEMISTRY

Longitudinal study on MRI intensity changes of Machado–Joseph disease: correlation between MRI findings and neuropathological changes

(2011) Yoshihiko Horimoto et al.   JOURNAL OF NEUROLOGY

The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis

(2011) Kirsten Kuhlbrodt et al.   NATURE CELL BIOLOGY

Axonal inclusions in spinocerebellar ataxia type 3

(2010) Kay Seidel et al.   ACTA NEUROPATHOLOGICA

Adenosine receptors and brain diseases: Neuroprotection and neurodegeneration

(2010) Catarina V. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Protein homeostasis and synaptic plasticity

(2010) Iván J Cajigas et al.   EMBO JOURNAL

A Role for the Ubiquitin-Proteasome System in Activity-Dependent Presynaptic Silencing

(2010) X. Jiang et al.   JOURNAL OF NEUROSCIENCE

Ubiquitination Acutely Regulates Presynaptic Neurotransmitter Release in Mammalian Neurons

(2010) G. V. Rinetti et al.   JOURNAL OF NEUROSCIENCE

Motor uncoordination and neuropathology in a transgenic mouse model of Machado–Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products

(2010) Anabela Silva-Fernandes et al.   NEUROBIOLOGY OF DISEASE

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

(2010) An-Hsun Chou et al.   NEUROBIOLOGY OF DISEASE

The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin–proteasome system

(2009) Ming-Chang Chiang et al.   HUMAN MOLECULAR GENETICS

Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats

(2009) João M. N. Duarte et al.   JOURNAL OF NEUROCHEMISTRY

Axonal Dysfunction in the Deep White Matter in Machado-Joseph Disease

(2009) Anelyssa D'Abreu et al.   JOURNAL OF NEUROIMAGING

Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by  -Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway

(2009) P. M. Canas et al.   JOURNAL OF NEUROSCIENCE

Adenosine A2Areceptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms

(2008) Liqun Yu et al.   ANNALS OF NEUROLOGY

Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease

(2008) Sandro Alves et al.   HUMAN MOLECULAR GENETICS

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

(2008) Jianjun Wang et al.   JOURNAL OF CELL BIOLOGY

An update on the mechanisms of the psychostimulant effects of caffeine

(2008) Sergi Ferré   JOURNAL OF NEUROCHEMISTRY

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Neuroinflammation and Oxidation/Nitration of  -Synuclein Linked to Dopaminergic Neurodegeneration

(2008) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

Adenosine A2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

(2008) Nelson Rebola et al.   NEURON