CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner

The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis

(2020) Mengnuo Chen et al.   Molecular Cancer

Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer

(2020) Yu Yang et al.   CANCER LETTERS

Dietary modifications for enhanced cancer therapy

(2020) Naama Kanarek et al.   NATURE

Role of amino acids in regulation of ROS balance in cancer

(2020) Emilie Jaune-Pons et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanism of RNA modification N6-methyladenosine in human cancer

(2020) Zijian Zhou et al.   Molecular Cancer

CircRNAs: biogenesis, functions, and role in drug-resistant Tumours

(2020) Shuo Ma et al.   Molecular Cancer

LINC00460-miR-149-5p/miR-150-5p-mutant p53 feedback loop promotes oxaliplatin resistance in colorectal cancer

(2020) Xiangfeng Meng et al.   Molecular Therapy-Nucleic Acids

Metabolic Reprogramming in Breast Cancer and Its Therapeutic Implications

(2019) Nishant Gandhi et al.   Cells

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress

(2019) Qidong Li et al.   Cell Metabolism

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer

(2019) Matthieu Lacroix et al.   Molecular Metabolism

Circular RNA Sequencing Identifies CircASAP1 as a Key Regulator in Hepatocellular Carcinoma Metastasis

(2019) Zhi‐Qiang Hu et al.   HEPATOLOGY

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes

(2018) Yajun Chen et al.   CELL DEATH AND DIFFERENTIATION

The why and how of amino acid analytics in cancer diagnostics and therapy

(2017) Friederike Manig et al.   JOURNAL OF BIOTECHNOLOGY

Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling

(2017) Jianwei Liao et al.   Molecular Cancer

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells

(2017) S Ros et al.   ONCOGENE

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype

(2016) Gregg L Semenza   EMBO JOURNAL

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

(2016) Michael E Pacold et al.   Nature Chemical Biology

p53 Protein-mediated Regulation of Phosphoglycerate Dehydrogenase (PHGDH) Is Crucial for the Apoptotic Response upon Serine Starvation

(2014) Yang Ou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Serine and glycine metabolism in cancer

(2014) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

An Alternative Pathway in Colorectal Carcinogenesis Based on the Mismatch Repair System and p53 Expression in Korean Patients with Sporadic Colorectal Cancer

(2012) Hyoung Ran Kim et al.   ANNALS OF SURGICAL ONCOLOGY

Microsatellite instability testing in Korean patients with colorectal cancer

(2012) Jung Ryul Oh et al.   Familial Cancer

How cancer metabolism is tuned for proliferation and vulnerable to disruption

(2012) Almut Schulze et al.   NATURE

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

(2012) Oliver D. K. Maddocks et al.   NATURE

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY