Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model

Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

(2021) Kathy Leung et al.   Eurosurveillance

Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein

(2021) Houriiyah Tegally et al.   NATURE

Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro

(2021) Martina Morokutti-Kurz et al.   PLoS One

Three Emerging Coronaviruses in Two Decades

(2020) Jeannette Guarner   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Remdesivir for Treatment of COVID-19: Combination of Pulmonary and IV Administration May Offer Aditional Benefit

(2020) Duxin Sun   AAPS Journal

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

(2020) Fabian Schmidt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro

(2020) Paul S. Kwon et al.   Cell Discovery

Spike mutation D614G alters SARS-CoV-2 fitness

(2020) Jessica A. Plante et al.   NATURE

Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application

(2019) Lee   Marine Drugs

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

(2018) Nina Derby et al.   Nature Communications

First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel

(2016) Barbara A. Friedland et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential

(2016) Sabrina Lusvarghi et al.   Viruses-Basel

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

(2015) Keith Levendosky et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

(2015) Tinoush Moulaei et al.   Retrovirology

Non-Clinical Safety Evaluation of Intranasal Iota-Carrageenan

(2015) Alexandra Hebar et al.   PLoS One

In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition

(2014) Aixa Rodríguez et al.   ANTIVIRAL RESEARCH

Carrageenan nasal spray in virus confirmed common cold: individual patient data analysis of two randomized controlled trials

(2014) Martin Koenighofer et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Zinc Acetate/Carrageenan Gels Exhibit Potent ActivityIn Vivoagainst High-Dose Herpes Simplex Virus 2 Vaginal and Rectal Challenge

(2011) José A. Fernández-Romero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Iota-Carrageenan Is a Potent Inhibitor of Influenza A Virus Infection

(2010) Andreas Leibbrandt et al.   PLoS One

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

(2009) B. R. O'Keefe et al.   JOURNAL OF VIROLOGY

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

(2009) B. R. O'Keefe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA