Whole body hypoxic preconditioning-mediated multiorgan protection in db/db mice via nitric oxide-BDNF-GSK-3β-Nrf2 signaling pathway

Cardiac Ischemic Preconditioning Promotes MG53 Secretion Through H 2 O 2 -Activated PKC-δ Signaling

(2020) Dan Shan et al.   CIRCULATION

Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice

(2020) Hongli Ma et al.   CLINICAL SCIENCE

Amelioration of diabetes-induced cognitive impairment by Transient Receptor Potential Vanilloid 2 (TRPV2) channel inhibitor: Behavioral and mechanistic study

(2020) P. Thapak et al.   NEUROCHEMISTRY INTERNATIONAL

Dietary α-Linolenic Acid Counters Cardioprotective Dysfunction in Diabetic Mice: Unconventional PUFA Protection

(2020) Jake S. Russell et al.   Nutrients

Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance via PTEN-mediated crosstalk between the PI3K/Akt and Erk/MAPKs signaling pathways in the skeletal muscles of db/db mice

(2020) Guang Chen et al.   Stem Cell Research & Therapy

Ischemic and hypoxic conditioning: Potential for protection of vital organs

(2019) Justin D. Sprick et al.   EXPERIMENTAL PHYSIOLOGY

Exercise and circulating BDNF: Mechanisms of release and implications for the design of exercise interventions

(2018) Jeremy James Walsh et al.   Applied Physiology Nutrition and Metabolism

ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection

(2018) Susana Cadenas   FREE RADICAL BIOLOGY AND MEDICINE

Aerobic exercise enhanced endothelium-dependent vasorelaxation in mesenteric arteries in spontaneously hypertensive rats: the role of melatonin

(2018) Fang Qiu et al.   HYPERTENSION RESEARCH

Brain-derived neurotrophic factor secreted by the cerebral endothelium: A new actor of brain function?

(2018) Christine Marie et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of l -arginine/SNAP/NO/cGMP/KATP channel signalling pathway in antinociceptive effect of α-terpineol in mice

(2018) Sara Safaripour et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Exercise preconditioning and low dose copper nanoparticles exhibits cardioprotection through targeting GSK-3β phosphorylation in ischemia/reperfusion induced myocardial infarction

(2018) Arun K. Sharma et al.   MICROVASCULAR RESEARCH

The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells

(2018) Harrison T. Supnick et al.   Oncotarget

Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation

(2018) Tuo Yang et al.   Redox Biology

Hypoxic preconditioning attenuates necroptotic neuronal death induced by global cerebral ischemia via Drp1-dependent signaling pathway mediated by CaMKIIα inactivation in adult rats

(2018) Lixuan Zhan et al.   FASEB JOURNAL

Involvement of Endothelin 1 in Remote Preconditioning-Induced Cardioprotection through connexin 43 and Akt/GSK-3β Signaling Pathway

(2018) Min Zhang et al.   Scientific Reports

Cardioprotection and improvement in endothelial-dependent vasodilation during late-phase of whole body hypoxic preconditioning in spontaneously hypertensive rats via VEGF and endothelin-1

(2018) Xing-Yu Hong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

UPLC-QTOFMS-based metabolomic analysis of the serum of hypoxic preconditioning mice

(2017) Jie Liu et al.   Molecular Medicine Reports

Interaction between nitric oxide signaling and gap junctions during ischemic preconditioning: Importance of S-nitrosylation vs. protein kinase G activation

(2017) Fei Xie et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes

(2017) Dajun Zhao et al.   Oxidative Medicine and Cellular Longevity

Neurobiology of local and intercellular BDNF signaling

(2017) Manju Sasi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet

(2017) Susan J. Burke et al.   Journal of Diabetes Research

Repression of the Antioxidant NRF2 Pathway in Premature Aging

(2016) Nard Kubben et al.   CELL

Brain BDNF levels are dependent on cerebrovascular endothelium-derived nitric oxide

(2016) Hayat Banoujaafar et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways

(2015) Thiago Bruder-Nascimento et al.   CLINICAL SCIENCE

High fat diet-induced diabetes in mice exacerbates cognitive deficit due to chronic hypoperfusion

(2015) Kristen L Zuloaga et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Late cardioprotection of exercise preconditioning against exhaustive exercise-induced myocardial injury by up-regulatation of connexin 43 expression in rat hearts

(2015) Kai Wang et al.   Asian Pacific Journal of Tropical Medicine

Riluzole Stimulates BDNF Release from Human Platelets

(2015) Patrick Türck et al.   Biomed Research International

GSK-3 as potential target for therapeutic intervention in cancer

(2015) James A. McCubrey et al.   Oncotarget

Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish (Danio rerio)

(2014) Katiucia Marques Capiotti et al.   BEHAVIOURAL BRAIN RESEARCH

Increased Risk of Subsequent Myocardial Infarction in Patients With Type 2 Diabetes: A Retrospective Cohort Study Using the U.K. General Practice Research Database

(2014) Huifang Liang et al.   DIABETES CARE

Increased BDNF Protein Expression after Ischemic Or PKC Epsilon Preconditioning Promotes Electrophysiologic Changes That Lead to Neuroprotection

(2014) Jake T Neumann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

BDNF secretion by human pulmonary artery endothelial cells in response to hypoxia

(2014) Martin Helan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitric oxide in the normal kidney and in patients with diabetic nephropathy

(2014) Paolo Tessari   JOURNAL OF NEPHROLOGY

Brain-derived neurotrophic factor in the airways

(2014) Y.S. Prakash et al.   PHARMACOLOGY & THERAPEUTICS

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling

(2013) Hannah J. Whittington et al.   CARDIOVASCULAR RESEARCH

Diabetes increases mortality after myocardial infarction by oxidizing CaMKII

(2013) Min Luo et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of TrkB agonist 7,8-dihydroxyflavone on sensory gating deficits in mice after administration of methamphetamine

(2013) Qian Ren et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Bitter Fate of the Sweet Heart: Impairment of Iron Homeostasis in Diabetic Heart Leads to Failure in Myocardial Protection by Preconditioning

(2013) Vladimir Vinokur et al.   PLoS One

Impact of Diabetes on Cardiovascular Disease: An Update

(2013) Alessandra Saldanha de Mattos Matheus et al.   International Journal of Hypertension

Low BDNF is associated with cognitive deficits in patients with type 2 diabetes

(2012) Yan Feng Zhen et al.   PSYCHOPHARMACOLOGY

Perconditioning and Postconditioning: Current Knowledge, Knowledge Gaps, Barriers to Adoption, and Future Directions

(2011) Jakob Vinten-Johansen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion

(2011) Robert M. Bell et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments