Comparative study of two isothiazolinone biocides, 1,2-benzisothiazolin-3-one (BIT) and 4,5-dichloro-2-n-octyl-isothiazolin-3-one (DCOIT), on barrier function and mitochondrial bioenergetics using murine brain endothelial cell line (bEND.3)

A Commonly Used Biocide 2-N-octyl-4-isothiazolin-3-oneInduces Blood–Brain Barrier Dysfunction via Cellular Thiol Modification and Mitochondrial Damage

(2021) Donghyun Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mine-site derived particulate matter exposure exacerbates neurological and pulmonary inflammatory outcomes in an autoimmune mouse model

(2021) Alexis Wilson et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

A Physiological-Based Pharmacokinetic Model For The Broad Spectrum Antimicrobial Zinc Pyrithione: II. Dermal Absorption And Dosimetry In The Rat

(2021) Gary L. Diamond et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

High concentration of blood cobalt is associated with the impairment of blood-brain barrier permeability

(2021) Zhigang Li et al.   CHEMOSPHERE

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

(2020) Vânia Silva et al.   MOLECULES

The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis

(2020) Anna Gerhartl et al.   Fluids and Barriers of the CNS

Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia

(2020) Shaoxing Liu et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Influence of bifentrin, a pyrethriod pesticide, on human colorectal HCT-116 cells attributed to alterations in oxidative stress involving mitochondrial apoptotic processes

(2020) Chayma Bouaziz et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke

(2020) Sajad Sarvari et al.   METABOLIC BRAIN DISEASE

Autophagy-mediated occludin degradation contributes to blood–brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models

(2020) Kyeong-A Kim et al.   Fluids and Barriers of the CNS

Gestational exposure to tebuconazole affects the development of rat fetal Leydig cells

(2020) Feifei Ma et al.   CHEMOSPHERE

Diazinon impairs bioenergetics and induces membrane permeability transition on mitochondria isolated from rat liver

(2020) Camila Araújo Miranda et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Cadmium-Induced Oxidative Stress: Focus on the Central Nervous System

(2020) Jacopo J. V. Branca et al.   Antioxidants

Preeclampsia and Increased Permeability Over the Blood–Brain Barrier: A Role of Vascular Endothelial Growth Receptor 2

(2020) Lina Bergman et al.   AMERICAN JOURNAL OF HYPERTENSION

Mitochondrial dysfunction in cardiovascular disease: Current status of translational research/clinical and therapeutic implications

(2020) Antonis S. Manolis et al.   MEDICINAL RESEARCH REVIEWS

Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species

(2020) Donghyun Kim et al.   Antioxidants

Advanced glycation end-products disrupt brain microvascular endothelial cell barrier: The role of mitochondria and oxidative stress

(2020) Anthony Dobi et al.   MICROVASCULAR RESEARCH

Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders

(2020) Masamichi Ikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanistic Interplay between Autophagy and Apoptotic Signaling in Endosulfan-induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity

(2019) Chunjuan Song et al.   TOXICOLOGICAL SCIENCES

Zinc accumulation in mitochondria promotes ischemia-induced BBB disruption through Drp1-dependent mitochondria fission

(2019) Zhifeng Qi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cerebrovascular plasticity: Processes that lead to changes in the architecture of brain microvessels

(2019) Max I Bogorad et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An insight into toxicity and human-health-related adverse consequences of cosmeceuticals — A review

(2019) Muhammad Bilal et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Multi-omics investigation reveals benzalkonium chloride disinfectants alter sterol and lipid homeostasis in the mouse neonatal brain

(2019) Josi M Herron et al.   TOXICOLOGICAL SCIENCES

Mitochondria and Critical Illness

(2019) Gerald S. Supinski et al.   CHEST

Exposure to graphene nanoparticles induces changes in measures of vascular/renal function in a load and form-dependent manner in mice

(2019) K. Krajnak et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Effects of Cadmium on ZO-1 Tight Junction Integrity of the Blood Brain Barrier

(2019) Jacopo Junio Valerio Branca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of mitochondrial DNA in oxidative damage induced by sodium arsenite in human bronchial epithelial cells

(2019) Jing Wu et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The regulation of autophagy in the pesticide-induced toxicity: Angel or demon?

(2019) Bingnan He et al.   CHEMOSPHERE

Blood-Brain Barrier Dysfunction in Ischemic Stroke: Targeting Tight Junctions and Transporters for Vascular Protection

(2018) Wazir Abdullahi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protonophoric action of triclosan causes calcium efflux from mitochondria, plasma membrane depolarization and bursts of miniature end-plate potentials

(2018) Lyudmila B. Popova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Isothiazolinone Content of US Residential Interior Wall Paint

(2018) Molly C. Goodier et al.   Dermatitis

Isothiazolinone derivatives and allergic contact dermatitis: a review and update

(2018) Anne Herman et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

(2018) Shaonan Hu et al.   MOLECULES

Measuring Liver Mitochondrial Oxygen Consumption and Proton Leak Kinetics to Estimate Mitochondrial Respiration in Holstein Dairy Cattle

(2018) Heidi A. Rossow et al.   Jove-Journal of Visualized Experiments

Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

(2018) Changjun Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Exposure to pesticides and the associated human health effects

(2017) Ki-Hyun Kim et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Occurrence and concentrations of isothiazolinones in detergents and cosmetics in Switzerland

(2016) Elena Garcia-Hidalgo et al.   CONTACT DERMATITIS

The toxicity of the three antifouling biocides DCOIT, TPBP and medetomidine to the marine pelagic copepod Acartia tonsa

(2016) Ida Wendt et al.   ECOTOXICOLOGY

Mechanism and kinetics of electrochemical degradation of uric acid using conductive-diamond anodes

(2016) Sondos Dbira et al.   ENVIRONMENTAL TECHNOLOGY

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Environmental Toxins and Parkinson's Disease

(2013) Samuel M. Goldman   Annual Review of Pharmacology and Toxicology

Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling

(2013) Alexander V. Zhdanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Airborne and systemic dermatitis, mimicking atopic dermatitis, caused by methylisothiazolinone in a young child

(2013) Olivier Aerts et al.   CONTACT DERMATITIS

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

A novel bioactivity of andrographolide fromAndrographis paniculataon cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial cell apoptosis

(2013) Ting-Lin Yen et al.   PHARMACEUTICAL BIOLOGY

Determination of isothiazolinone preservatives in cosmetics and household products by matrix solid-phase dispersion followed by high-performance liquid chromatography–tandem mass spectrometry

(2012) Gerardo Alvarez-Rivera et al.   JOURNAL OF CHROMATOGRAPHY A

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

(2012) A Perelman et al.   Cell Death & Disease

Analysis of isothiazolinone biocides in paper for food packaging by ultra-high-performance liquid chromatography–tandem mass spectrometry

(2010) Q.-B. Lin et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Involvement of ROS in BBB dysfunction

(2009) Pamela B. L. Pun et al.   FREE RADICAL RESEARCH

Structure–activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2

(2008) Jürgen Arning et al.   TOXICOLOGY