The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis

Claudin-3-deficient C57BL/6J mice display intact brain barriers

(2019) Mariana Castro Dias et al.   Scientific Reports

Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway

(2019) Shyanne Page et al.   NEUROMOLECULAR MEDICINE

Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

(2019) Erica Tornabene et al.   PLoS One

Claudin-12 is not required for blood–brain barrier tight junction function

(2019) Mariana Castro Dias et al.   Fluids and Barriers of the CNS

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport

(2018) Szilvia Veszelka et al.   Frontiers in Molecular Neuroscience

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Barrier properties and transcriptome expression in human iPSC-derived models of the blood-brain barrier

(2018) Louise Delsing et al.   STEM CELLS

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

(2018) Liqun He et al.   Scientific Data

Claudin-1 dependent destabilization of the blood-brain barrier in chronic stroke

(2018) Nikola Sladojevic et al.   JOURNAL OF NEUROSCIENCE

Expression and Functional Characterization of Drug Transporters in Brain Microvascular Endothelial Cells Derived from Human Induced Pluripotent Stem Cells

(2018) Toshiki Kurosawa et al.   MOLECULAR PHARMACEUTICS

Whole exome sequencing: a state-of-the-art approach for defining (and exploring!) genetic landscapes in pediatric nephrology

(2017) Ashima Gulati et al.   PEDIATRIC NEPHROLOGY

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury

(2017) Winfried Neuhaus   Frontiers in Molecular Neuroscience

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells

(2017) Antje Appelt-Menzel et al.   Stem Cell Reports

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Redox Regulation of Cell Contacts by Tricellulin and Occludin: Redox-Sensitive Cysteine Sites in Tricellulin Regulate Both Tri- and Bicellular Junctions in Tissue Barriers as Shown in Hypoxia and Ischemia

(2015) Jimmi Cording et al.   ANTIOXIDANTS & REDOX SIGNALING

Altered glycaemia differentially modulates efflux transporter expression and activity in hCMEC/D3 cell line

(2015) Ravi K. Sajja et al.   NEUROSCIENCE LETTERS

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier

(2014) Winfried Neuhaus et al.   Frontiers in Cellular Neuroscience

Inhibition of Proteasomal Glucocorticoid Receptor Degradation Restores Dexamethasone-Mediated Stabilization of the Blood–Brain Barrier After Traumatic Brain Injury*

(2013) Serge C. Thal et al.   CRITICAL CARE MEDICINE

Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model

(2012) Sumio Ohtsuki et al.   MOLECULAR PHARMACEUTICS

Design and validation issues in RNA-seq experiments

(2011) Z. Fang et al.   BRIEFINGS IN BIOINFORMATICS

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

Addition of NMDA-receptor antagonist MK801 during oxygen/glucose deprivation moderately attenuates the upregulation of glucose uptake after subsequent reoxygenation in brain endothelial cells

(2011) Winfried Neuhaus et al.   NEUROSCIENCE LETTERS

Glucocorticoid Insensitivity at the Hypoxic Blood–Brain Barrier Can Be Reversed by Inhibition of the Proteasome

(2011) Christoph Kleinschnitz et al.   STROKE

Peroxisome Proliferator-Activated Receptor-α Activation Protects Brain Capillary Endothelial Cells from Oxygen-Glucose Deprivation-Induced Hyperpermeability in the Blood-Brain Barrier

(2009) Caroline Mysiorek et al.   CURRENT NEUROVASCULAR RESEARCH

Validation of in vitro cell culture models of the blood–brain barrier: Tightness characterization of two promising cell lines

(2008) Winfried Neuhaus et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Differential effects of hydrocortisone and TNFα on tight junction proteins in anin vitromodel of the human blood-brain barrier

(2008) Carola Förster et al.   JOURNAL OF PHYSIOLOGY-LONDON