Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

Humidifier disinfectant and use characteristics associated with lung injury in Korea

(2019) Seung‐Hun Ryu et al.   INDOOR AIR

Electrochemical degradation of methylisothiazolinone by using Ti/SnO2-Sb2O3/α, β-PbO2 electrode: Kinetics, energy efficiency, oxidation mechanism and degradation pathway

(2019) Yingcai Wang et al.   CHEMICAL ENGINEERING JOURNAL

Simultaneous Quantitative Analysis of Six Isothiazolinones in Water-Based Adhesive Used for Food Contact Materials by High-Performance Liquid Chromatography–Tandem Mass Spectrometry (HPLC–MS/MS)

(2019) Huaining Zhong et al.   MOLECULES

Determination of booster biocides in sediments by focused ultrasound-assisted extraction and stir bar sorptive extraction–thermal desorption–gas chromatography–mass spectrometry

(2019) E. García et al.   MICROCHEMICAL JOURNAL

Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells

(2019) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury

(2018) Eun Lee et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Long-lasting isothiazolinone-based biocide obtained by encapsulation in micron-sized mesoporous matrices

(2018) Lucas E. Mardones et al.   PROGRESS IN ORGANIC COATINGS

MI (2-methyl-4-isothiazolin-3-one) contained in detergents is not detectable in machine washed textiles

(2018) Maja A. Hofmann et al.   Clinical and Translational Allergy

Simultaneous quantitative analysis of four isothiazolinones and 3-iodo-2-propynyl butyl carbamate present in hygienic consumer products

(2018) Jin Ju Heo et al.   Environmental Engineering Research

Metal-free intramolecular N-S bond formation to access benzisothiazol-3-ones

(2018) KE YANG et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Isothiazolinone Content of US Residential Interior Wall Paint

(2018) Molly C. Goodier et al.   Dermatitis

Isothiazolinone derivatives and allergic contact dermatitis: a review and update

(2018) Anne Herman et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

CMIT/MIT induce apoptosis and inflammation in alveolar epithelial cells through p38/JNK/ERK1/2 signaling pathway

(2018) Jooyeon Lee et al.   Molecular & Cellular Toxicology

Biocide Runoff from Building Facades: Degradation Kinetics in Soil

(2017) Ulla E. Bollmann et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

SeaNine 211 as antifouling biocide: A coastal pollutant of emerging concern

(2017) Lianguo Chen et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Self-sensitized photodegradation of benzisothiazolinone by low-pressure UV-C irradiation: Kinetics, mechanisms, and the effect of media

(2017) Ting Wang et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children

(2017) Hyun-Ju Cho et al.   PLoS One

Photodegradation of octylisothiazolinone and semi-field emissions from facade coatings

(2017) Ulla E. Bollmann et al.   Scientific Reports

Cross-reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay

(2016) J.F. Schwensen et al.   BRITISH JOURNAL OF DERMATOLOGY

Study on the removal of benzisothiazolinone biocide and its toxicity: The effectiveness of ozonation

(2016) Ang Li et al.   CHEMICAL ENGINEERING JOURNAL

The fate of two isothiazolinone biocides, 5-chloro-2-methylisothiazol-3(2H)-one (CMI) and 2-methylisothiazol-3(2H)-one (MI), in liquid air fresheners and assessment of inhalation exposure

(2016) Seon-Kyung Park et al.   CHEMOSPHERE

Occurrence and concentrations of isothiazolinones in detergents and cosmetics in Switzerland

(2016) Elena Garcia-Hidalgo et al.   CONTACT DERMATITIS

Octylisothiazolinone, an additional cause of allergic contact dermatitis caused by leather: case series and potential implications for the study of cross-reactivity with methylisothiazolinone

(2016) Olivier Aerts et al.   CONTACT DERMATITIS

Anogenital allergic contact dermatitis caused by methylchloroisothiazolinone, methylisothiazolinone and topical clotrimazole with subsequent generalized exanthem triggered by oral fluconazole

(2016) Shaaira Nasir et al.   CONTACT DERMATITIS

Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening

(2016) Zhi-Bin Tong et al.   JOURNAL OF APPLIED TOXICOLOGY

An efficient approach to construct benzisothiazol-3(2H)-ones via copper-catalyzed consecutive reaction of 2-halobenzamides and carbon disulfide

(2016) Ting Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Prevalence of contact allergy in the general population in different European regions

(2015) T.L. Diepgen et al.   BRITISH JOURNAL OF DERMATOLOGY

Degradation kinetics of a potent antifouling agent, butenolide, under various environmental conditions

(2015) Lianguo Chen et al.   CHEMOSPHERE

Methylchloroisothiazolinone and methylisothiazolinone contact allergy: an occupational perspective

(2015) Rachel Urwin et al.   CONTACT DERMATITIS

Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry

(2015) James B. Wittenberg et al.   JOURNAL OF SEPARATION SCIENCE

Isothiazolinones in commercial products at Danish workplaces

(2014) Ulrik Fischer Friis et al.   CONTACT DERMATITIS

Occupational contact dermatitis in blue-collar workers: results from a multicentre study from the Danish Contact Dermatitis Group (2003-2012)

(2014) Jakob F. Schwensen et al.   CONTACT DERMATITIS

The dramatic increase in the rate of methylisothiazolinone contact allergy in Belgium: a multicentre study

(2014) Olivier Aerts et al.   CONTACT DERMATITIS

Emission of Isothiazolinones from Water-Based Paints

(2014) Michael D. Lundov et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Analysis of isothiazolinone preservatives in polyvinyl alcohol cooling towels used in Japan

(2014) Tsuyoshi Kawakami et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Patch test results of hand eczema patients: relation to clinical types

(2014) M.B. Boonstra et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Major Pesticides Are More Toxic to Human Cells Than Their Declared Active Principles

(2014) Robin Mesnage et al.   Biomed Research International

Key Role for Efflux in the Preservative Susceptibility and Adaptive Resistance of Burkholderia cepacia Complex Bacteria

(2013) Laura Rushton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preparation of benzisothiazolones from 2-bromobenzamides and sulfur under copper catalysis conditions

(2013) V. Krasikova et al.   Chemistry of Heterocyclic Compounds

Determination of Preservatives in Cosmetics, Cleaning Agents and Pharmaceuticals Using Fast Liquid Chromatography

(2013) Irena Baranowska et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Three-phase hollow-fiber liquid-phase microextraction combined with HPLC-UV for the determination of isothiazolinone biocides in adhesives used for food packaging materials

(2013) Milton Rosero-Moreano et al.   JOURNAL OF SEPARATION SCIENCE

Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography–tandem mass spectrometry

(2012) Zhi-Feng Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Determination of 19 Preservatives in Various Matrices by High-Performance Liquid Chromatography

(2012) Na-Ri Cha et al.   ANALYTICAL LETTERS

Determination of isothiazolinone preservatives in cosmetics and household products by matrix solid-phase dispersion followed by high-performance liquid chromatography–tandem mass spectrometry

(2012) Gerardo Alvarez-Rivera et al.   JOURNAL OF CHROMATOGRAPHY A

Concise Approach to Benzisothiazol-3(2H)-one via Copper-Catalyzed Tandem Reaction of o-Bromobenzamide and Potassium Thiocyanate in Water

(2012) Fei Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Danger from the workplace: allergic contact dermatitis from the first exposure to isothiazolinones

(2011) Robert Willi et al.   CONTACT DERMATITIS

Determination of biocides and pesticides by on-line solid phase extraction coupled with mass spectrometry and their behaviour in wastewater and surface water

(2010) Heinz Singer et al.   ENVIRONMENTAL POLLUTION

Analysis of isothiazolinone biocides in paper for food packaging by ultra-high-performance liquid chromatography–tandem mass spectrometry

(2010) Q.-B. Lin et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Determination of biocides as well as some biocide metabolites from facade run-off waters by solid phase extraction and high performance liquid chromatographic separation and tandem mass spectrometry detection

(2010) K. Bester et al.   JOURNAL OF CHROMATOGRAPHY A

Trace analysis of isothiazolinones in water samples by large-volume direct injection liquid chromatography tandem mass spectrometry

(2010) P. Speksnijder et al.   JOURNAL OF CHROMATOGRAPHY A

Analyzing Cytotoxic Effects of Selected Isothiazol-3-one Biocides Using the Toxic Ratio Concept and Structure−Activity Relationship Considerations

(2009) Jürgen Arning et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure–activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2

(2008) Jürgen Arning et al.   TOXICOLOGY

Simultaneous determination of 21 preservatives in cosmetics by ultra performance liquid chromatography

(2008) T. Wu et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE