miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway

MicroRNA‑22 alleviates inflammation in ischemic stroke via p38 MAPK pathways

(2019) Huixiao Dong et al.   Molecular Medicine Reports

Inhibition of miR-19a protects neurons against ischemic stroke through modulating glucose metabolism and neuronal apoptosis

(2019) Xiao-Li Ge et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition

(2019) Longjun Li et al.   CELL DEATH AND DIFFERENTIATION

microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinoma

(2018) Xue-Mei Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Cerebral ischemia and neuroregeneration

(2018) HungWen Lin et al.   Neural Regeneration Research

Anti-Inflammatory MicroRNAs and Their Potential for Inflammatory Diseases Treatment

(2018) Alireza Tahamtan et al.   Frontiers in Immunology

Regulation of microRNA function in animals

(2018) Luca F. R. Gebert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress

(2018) Sungjin Kim et al.   Cell Reports

The Role of Sirt1 in Ischemic Stroke: Pathogenesis and Therapeutic Strategies

(2018) Jun-Fang Zhang et al.   Frontiers in Neuroscience

Capsaicin protects cortical neurons against ischemia/reperfusion injury via down-regulating NMDA receptors

(2017) Ming Huang et al.   EXPERIMENTAL NEUROLOGY

Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response

(2017) Wei Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses

(2017) Tao Jiang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion

(2017) Danying Su et al.   JOURNAL OF NEUROIMMUNOLOGY

SIRT1 confers protection against ischemia/reperfusion injury in cardiomyocytes via regulation of uncoupling protein 2 expression

(2017) Min Deng et al.   Molecular Medicine Reports

FOXO Transcriptional Factors and Long-Term Living

(2017) Ghulam Murtaza et al.   Oxidative Medicine and Cellular Longevity

The FoxO3 gene and cause-specific mortality

(2016) Bradley J. Willcox et al.   AGING CELL

Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction

(2016) Fuyang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats

(2015) Mingge Ding et al.   Cardiovascular Diabetology

Inflammatory Responses in Brain Ischemia

(2015) Masahito Kawabori et al.   CURRENT MEDICINAL CHEMISTRY

Sphingosine kinase 1 as an anticancer therapeutic target

(2015) Ying Gao et al.   Drug Design Development and Therapy

Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity

(2015) Frederic Boal et al.   Scientific Reports

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Link Between Oxidative Stress and Acute Brain Ischemia

(2013) Djordje Radak et al.   ANGIOLOGY

Involvement of the FoxO3a pathway in the ischemia/reperfusion injury of cardiac microvascular endothelial cells

(2013) Xu-Feng Qi et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

SIRT1 Protein, by Blocking the Activities of Transcription Factors FoxO1 and FoxO3, Inhibits Muscle Atrophy and Promotes Muscle Growth

(2013) Donghoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian Sirt1: insights on its biological functions

(2011) Shahedur Rahman et al.   Cell Communication and Signaling

SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions

(2009) Tong Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS