The Role of Sirt1 in Ischemic Stroke: Pathogenesis and Therapeutic Strategies

MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset

(2018) Götz Thomalla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

(2018) Gregory W. Albers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

(2018) Raul G. Nogueira et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia

(2018) Tao Chen et al.   Redox Biology

GLUT4 Mobilization Supports Energetic Demands of Active Synapses

(2017) Ghazaleh Ashrafi et al.   NEURON

Magnolol attenuates the inflammation and apoptosis through the activation of SIRT1 in experimental stroke rats

(2017) Dong-Quan Kou et al.   Pharmacological Reports

Neuronal SIRT1 (Silent Information Regulator 2 Homologue 1) Regulates Glycolysis and Mediates Resveratrol-Induced Ischemic Tolerance

(2017) Kevin B. Koronowski et al.   STROKE

Nrf2/antioxidant defense pathway is involved in the neuroprotective effects of Sirt1 against focal cerebral ischemia in rats after hyperbaric oxygen preconditioning

(2016) Fen Xue et al.   BEHAVIOURAL BRAIN RESEARCH

Curcumin pretreatment attenuates inflammation and mitochondrial dysfunction in experimental stroke: The possible role of Sirt1 signaling

(2016) Yanping Miao et al.   BRAIN RESEARCH BULLETIN

Resveratrol provides neuroprotection by inhibiting phosphodiesterases and regulating the cAMP/AMPK/SIRT1 pathway after stroke in rats

(2016) Dan Wan et al.   BRAIN RESEARCH BULLETIN

Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function

(2016) SoRi Jang et al.   NEURON

The Importance of Considering Sex Differences in Translational Stroke Research

(2016) Hilda Ahnstedt et al.   Translational Stroke Research

Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment

(2015) Giulio Maria Pasinetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson’s disease patients

(2015) Shahidee Zainal Abidin et al.   BMC Neurology

Calorie restriction attenuates cerebral ischemic injury via increasing SIRT1 synthesis in the rat

(2015) Mingzi Ran et al.   BRAIN RESEARCH

Salvianolic acid B attenuates apoptosis and inflammation via SIRT1 activation in experimental stroke rats

(2015) Hongdi Lv et al.   BRAIN RESEARCH BULLETIN

SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow

(2015) Yorito Hattori et al.   NEUROREPORT

Resveratrol Preconditioning Induces a Novel Extended Window of Ischemic Tolerance in the Mouse Brain

(2015) Kevin B. Koronowski et al.   STROKE

Neuronal autophagy: Going the distance to the axon

(2014) Zhenyu Yue et al.   Autophagy

Resveratrol Protects Neurons and the Myocardium by Reducing Oxidative Stress and Ameliorating Mitochondria Damage in a Cerebral Ischemia Rat Model

(2014) Ran Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Signaling pathways leading to ischemic mitochondrial neuroprotection

(2014) John W. Thompson et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

A Critical Role for Interferon Regulatory Factor 9 in Cerebral Ischemic Stroke

(2014) H.-Z. Chen et al.   JOURNAL OF NEUROSCIENCE

SIRT1 in Neurodevelopment and Brain Senescence

(2014) A. Zara Herskovits et al.   NEURON

Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia

(2014) B. Fu et al.   NEUROSCIENCE

Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase

(2014) Yorito Hattori et al.   STROKE

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

Sirt1 Mediates Hyperbaric Oxygen Preconditioning-Induced Ischemic Tolerance in Rat Brain

(2013) Wenjun Yan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke

(2013) Olivia Hurtado et al.   JOURNAL OF NEUROCHEMISTRY

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

SIRT1 Regulation Modulates Stroke Outcome

(2013) Valérie Petegnief et al.   Translational Stroke Research

SIRT1 metabolic actions: Integrating recent advances from mouse models

(2013) Marie Boutant et al.   Molecular Metabolism

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Revisiting the timing hypothesis: Biomarkers that define the therapeutic window of estrogen for stroke

(2012) Farida Sohrabji et al.   HORMONES AND BEHAVIOR

Acute Resveratrol Treatment Modulates Multiple Signaling Pathways in the Ischemic Brain

(2012) Jin A. Shin et al.   NEUROCHEMICAL RESEARCH

A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia

(2012) Shadia E. Nada et al.   NEUROCHEMISTRY INTERNATIONAL

The neurobiology of sirtuins and their role in neurodegeneration

(2012) Gizem Donmez   TRENDS IN PHARMACOLOGICAL SCIENCES

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

SIRT1 Acts as a Modulator of Neointima Formation Following Vascular Injury in Mice

(2011) Li Li et al.   CIRCULATION RESEARCH

Stroke and the immune system: from pathophysiology to new therapeutic strategies

(2011) Richard Macrez et al.   LANCET NEUROLOGY

Leptin Reduces Infarct Size in Association with Enhanced Expression of CB2, TRPV1, SIRT-1 and Leptin Receptor

(2010) Yosefa Avraham et al.   CURRENT NEUROVASCULAR RESEARCH

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

Resveratrol as a Therapeutic Agent for Neurodegenerative Diseases

(2010) Albert Y. Sun et al.   MOLECULAR NEUROBIOLOGY

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α Expression in experimental stroke

(2010) Hai-rong Zhu et al.   NEUROPHARMACOLOGY

Stroke in Women: Disparities and Outcomes

(2010) Rebecca W. Persky et al.   Current Cardiology Reports

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator

(2009) Gregory J. del Zoppo et al.   STROKE

Estimated 10-year stroke risk by region and race in the United States

(2008) Mary Cushman et al.   ANNALS OF NEUROLOGY

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

(2008) J. Weber et al.   CURRENT MEDICINAL CHEMISTRY

Transient Hypoxia Stimulates Mitochondrial Biogenesis in Brain Subcortex by a Neuronal Nitric Oxide Synthase-Dependent Mechanism

(2008) D. R. Gutsaeva et al.   JOURNAL OF NEUROSCIENCE

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Mechanisms of ischemic brain damage

(2008) Kristian P. Doyle et al.   NEUROPHARMACOLOGY

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death

(2008) Suping Wang et al.   STROKE

Food restriction attenuates ischemia-induced spatial learning and memory deficits despite extensive CA1 ischemic injury

(2007) Marie-Claude Roberge et al.   BEHAVIOURAL BRAIN RESEARCH

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy

(2007) John et al.   Frontiers in Bioscience-Landmark