Optimization of N-Phenylpropenoyl-l-amino Acids as Potent and Selective Inducible Nitric Oxide Synthase Inhibitors for Parkinson’s Disease

MiR ‐302b‐5p enhances the neuroprotective effect of IGF ‐1 in methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced Parkinson's disease by regulating inducible nitric‐oxide synthase

(2020) Xiaorui Cui et al.   CELL BIOCHEMISTRY AND FUNCTION

Optimization of Blood–Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold

(2019) Ha T. Do et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inducible nitric oxide synthase: Regulation, structure, and inhibition

(2019) Maris A. Cinelli et al.   MEDICINAL RESEARCH REVIEWS

Inducible nitric oxide synthase inhibitors: A comprehensive update

(2019) Richa Minhas et al.   MEDICINAL RESEARCH REVIEWS

Potential new therapies against a toxic relationship

(2019) Lais S. Rodrigues et al.   BEHAVIOURAL PHARMACOLOGY

Development of a SPR aptasensor containing oriented aptamer for direct capture and detection of tetracycline in multiple honey samples

(2018) Sai Wang et al.   BIOSENSORS & BIOELECTRONICS

Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo

(2018) Xiao-Long Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement

(2017) XiaoLong Hu et al.   NEUROPHARMACOLOGY

NADPH oxidase-derived H 2 O 2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease

(2017) Liyan Hou et al.   Redox Biology

Surface Plasmon Resonance (SPR) Biosensors in Pharmaceutical Analysis

(2015) Andreea Olaru et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

Effect of opicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity and motor fluctuations in patients with Parkinson's disease

(2015) J. J. Ferreira et al.   EUROPEAN JOURNAL OF NEUROLOGY

CETSA: a target engagement assay with potential to transform drug discovery

(2015) Annika Jenmalm Jensen et al.   Future Medicinal Chemistry

Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration

(2015) Durga Praveen Meka et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacological Treatment of Parkinson Disease

(2014) Barbara S. Connolly et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The cellular thermal shift assay for evaluating drug target interactions in cells

(2014) Rozbeh Jafari et al.   Nature Protocols

UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances l-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset

(2014) Philippe Huot et al.   NEUROPHARMACOLOGY

Probenecid potentiates MPTP/MPP+toxicity by interference with cellular energy metabolism

(2013) Daniel Alvarez-Fischer et al.   JOURNAL OF NEUROCHEMISTRY

Monoamine Oxidase B Inhibitors for the Treatment of Parkinsonʼs Disease

(2011) Anthony H.V. Schapira   CNS DRUGS

Determination of Ensemble-Average Pairwise Root Mean-Square Deviation from Experimental B-Factors

(2010) Antonija Kuzmanic et al.   BIOPHYSICAL JOURNAL

Neuroprotection by the selective iNOS inhibitor GW274150 in a model of Parkinson disease

(2010) Lauren Broom et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neurogenesis in Neurotoxin-induced Animal Models for Parkinson's Disease-A Review of the Current Status

(2009) Xi Jun He et al.   Journal of Toxicologic Pathology

Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats

(2008) Caroline Capitelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Discovery of a series of aminopiperidines as novel iNOS inhibitors

(2007) Bertrand Le Bourdonnec et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deficiency of Inducible Nitric Oxide Synthase Protects Against MPTP Toxicity In Vivo

(2003) Thomas Dehmer et al.   JOURNAL OF NEUROCHEMISTRY