Nontypeable Haemophilus influenzae P5 Binds Human C4b-Binding Protein, Promoting Serum Resistance

Complement evasion by the human respiratory tract pathogens Haemophilus influenzae and Moraxella catarrhalis

(2020) Kristian Riesbeck   FEBS LETTERS

Decreased prevalence of Moraxella catarrhalis in addition to Streptococcus pneumoniae in children with upper respiratory tract infection after introduction of conjugated pneumococcal vaccine: a retrospective cohort study

(2020) N. Littorin et al.   CLINICAL MICROBIOLOGY AND INFECTION

Epidemiology of Haemophilus influenzae in the Republic of Ireland, 2010–2018

(2020) Martha McElligott et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing

(2020) Maisem Laabei et al.   Frontiers in Immunology

The Laminin Interactome: A Multifactorial Laminin-Binding Strategy by Nontypeable Haemophilus influenzae for Effective Adherence and Colonization

(2019) Yu-Ching Su et al.   JOURNAL OF INFECTIOUS DISEASES

The hijackers guide to escaping complement: Lessons learned from pathogens

(2019) David Ermert et al.   MOLECULAR IMMUNOLOGY

Panel 7 – Pathogenesis of otitis media – a review of the literature between 2015 and 2019

(2019) R.B. Thornton et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Widespread of non‐typeable Haemophilus influenzae with high genetic diversity after two decades use of Hib vaccine in China

(2019) Qiaoli Dong et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development

(2018) Farshid Jalalvand et al.   Expert Review of Vaccines

Haemophilus influenzaegenome evolution during persistence in the human airways in chronic obstructive pulmonary disease

(2018) Melinda M. Pettigrew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential distribution of IgA-protease genotypes in mucosal and invasive isolates of Haemophilus influenzae in Sweden

(2018) Fredrik Resman et al.   BMC INFECTIOUS DISEASES

Non-typeable Haemophilus influenzae invasive blood isolates are mainly phosphorylcholine negative and show decreased complement-mediated killing in comparison to colonizing isolates from the oropharynx, which is associated with lower binding of IgM and CRP to the bacterial surface

(2018) Jeroen D. Langereis et al.   INFECTION AND IMMUNITY

The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface

(2018) Kashif S. Haleem et al.   INFECTION AND IMMUNITY

Increasing trend in invasive non-typeable Haemophilus influenzae disease and molecular characterization of the isolates, Italy, 2012–2016

(2018) Maria Giufrè et al.   VACCINE

The Interplay Between Immune Response and Bacterial Infection in COPD: Focus Upon Non-typeable Haemophilus influenzae

(2018) Yu-Ching Su et al.   Frontiers in Immunology

Factor H–IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial PathogenStreptococcus pyogenes

(2017) Anna M. Blom et al.   JOURNAL OF IMMUNOLOGY

Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia

(2016) Naomi J. Gadsby et al.   CLINICAL INFECTIOUS DISEASES

C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend

(2016) David Ermert et al.   IMMUNOLOGY LETTERS

A Novel Factor H–Fc Chimeric Immunotherapeutic Molecule againstNeisseria gonorrhoeae

(2016) Jutamas Shaughnessy et al.   JOURNAL OF IMMUNOLOGY

Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable Haemophilus influenzae

(2016) Sandy M. Wong et al.   Frontiers in Cellular and Infection Microbiology

A Novel Interaction between Complement Inhibitor C4b-binding Protein and Plasminogen That Enhances Plasminogen Activation

(2015) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haemophilus influenzaeP4 Interacts With Extracellular Matrix Proteins Promoting Adhesion and Serum Resistance

(2015) Yu-Ching Su et al.   JOURNAL OF INFECTIOUS DISEASES

Nasopharyngeal and Adenoid Colonization by Haemophilus influenzae and Haemophilus parainfluenzae in Children Undergoing Adenoidectomy and the Ability of Bacterial Isolates to Biofilm Production

(2015) Urszula Kosikowska et al.   MEDICINE

Carriage of Haemophilus influenzae is associated with pneumococcal vaccination in Italian children

(2015) Romina Camilli et al.   VACCINE

Persistence of non-typeableHaemophilus Influenzaein the pharynx of children with adenotonsillar hypertrophy after treatment with azithromycin

(2015) O. Olszewska-Sosińska et al.   Pathogens and Disease

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Relative Contribution of P5 and Hap Surface Proteins to Nontypable Haemophilus influenzae Interplay with the Host Upper and Lower Airways

(2015) Begoña Euba et al.   PLoS One

Fusion Protein Comprising Factor H Domains 6 and 7 and Human IgG1 Fc as an Antibacterial Immunotherapeutic

(2014) Jutamas Shaughnessy et al.   Clinical and Vaccine Immunology

Haemophilus influenzae Interacts with the Human Complement Inhibitor Factor H

(2014) T. Hallstrom et al.   JOURNAL OF IMMUNOLOGY

Identification of a Haemophilus influenzae Factor H-Binding Lipoprotein Involved in Serum Resistance

(2014) C. Fleury et al.   JOURNAL OF IMMUNOLOGY

What is behind the ear drum? The microbiology of otitis media and the nasopharyngeal flora in children in the era of pneumococcal vaccination

(2014) Nikki Mills et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Binding of human factor H to outer membrane protein P5 of non-typeableHaemophilus influenzaecontributes to complement resistance

(2014) Jeroen D. Langereis et al.   MOLECULAR MICROBIOLOGY

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Outer Membrane Protein P5 Is Required for Resistance of Nontypeable Haemophilus influenzae to Both the Classical and Alternative Complement Pathways

(2013) Charles V. Rosadini et al.   INFECTION AND IMMUNITY

Binding of Complement Inhibitor C4b-binding Protein to a Highly VirulentStreptococcus pyogenesM1 Strain Is Mediated by Protein H and Enhances Adhesion to and Invasion of Endothelial Cells

(2013) David Ermert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haemophilus influenzae Resides in Tonsils and Uses Immunoglobulin D Binding as an Evasion Strategy

(2013) Kalpana Singh et al.   JOURNAL OF INFECTIOUS DISEASES

Haemophilus influenzaeacquires vitronectin via the ubiquitous Protein F to subvert host innate immunity

(2013) Yu-Ching Su et al.   MOLECULAR MICROBIOLOGY

Lung microbiology and exacerbations in COPD

(2012) Sebastian Johnston et al.   International Journal of Chronic Obstructive Pulmonary Disease

Molecular Basis of Increased Serum Resistance among Pulmonary Isolates of Non-typeable Haemophilus influenzae

(2011) Shigeki Nakamura et al.   PLoS Pathogens

Invasive disease caused by Haemophilus influenzae in Sweden 1997–2009; evidence of increasing incidence and clinical burden of non-type b strains

(2010) F. Resman et al.   CLINICAL MICROBIOLOGY AND INFECTION

Binding of Complement Regulators to Invasive NontypeableHaemophilus influenzaeIsolates Is Not Increased Compared to Nasopharyngeal Isolates, but Serum Resistance Is Linked to Disease Severity

(2010) Teresia Hallström et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Haemophilus influenzae and the complement system

(2010) Teresia Hallström et al.   TRENDS IN MICROBIOLOGY

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

(2009) A. Dieudonne-Vatran et al.   JOURNAL OF IMMUNOLOGY

Nontypeable Haemophilus influenzae Protein E Binds Vitronectin and Is Important for Serum Resistance

(2009) T. Hallstrom et al.   JOURNAL OF IMMUNOLOGY