The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2

(2017) Sadam Yaseen et al.   FASEB JOURNAL

Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo

(2017) Ninette Genster et al.   Scientific Reports

Pneumococcal 6-Phospho-β-Glucosidase (BglA3) Is Involved in Virulence and Nutrient Metabolism

(2015) Vanessa Sofia Terra et al.   INFECTION AND IMMUNITY

Pneumococcal Adhesins PavB and PspC Are Important for the Interplay with Human Thrombospondin-1

(2015) Ulrike Binsker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement

(2015) Andrew P. Herbert et al.   JOURNAL OF IMMUNOLOGY

Lactate Dehydrogenase Is the Key Enzyme for Pneumococcal Pyruvate Metabolism and Pneumococcal Survival in Blood

(2014) Paula Gaspar et al.   INFECTION AND IMMUNITY

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection

(2014) Y. M. Ali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Choline-binding Protein PspC ofStreptococcus pneumoniaeInteracts with the C-terminal Heparin-binding Domain of Vitronectin

(2013) Sylvia Voss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion

(2012) V. Agarwal et al.   JOURNAL OF IMMUNOLOGY

Pneumococcal Surface Protein A Inhibits Complement Deposition on the Pneumococcal Surface by Competing with the Binding of C-Reactive Protein to Cell-Surface Phosphocholine

(2012) R. Mukerji et al.   JOURNAL OF IMMUNOLOGY

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

(2012) Youssif M. Ali et al.   PLoS Pathogens

Complement in health and disease

(2011) Maria V. Carroll et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

(2011) W. J. Schwaeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotype-Related Variation in Susceptibility to Complement Deposition and Opsonophagocytosis among Clinical Isolates of Streptococcus pneumoniae

(2010) M. Melin et al.   INFECTION AND IMMUNITY

Paths reunited: Initiation of the classical and lectin pathways of complement activation

(2009) Russell Wallis et al.   IMMUNOBIOLOGY

The Streptococcus pneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms

(2009) C. Hyams et al.   INFECTION AND IMMUNITY

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

(2009) A. Dieudonne-Vatran et al.   JOURNAL OF IMMUNOLOGY

The pneumococcus: why a commensal misbehaves

(2009) Jeffrey N. Weiser   JOURNAL OF MOLECULAR MEDICINE-JMM

The global epidemiology of childhood pneumonia 20 years on

(2008) J Anthony Scott   BULLETIN OF THE WORLD HEALTH ORGANIZATION