Xuebijing injection in septic rats mitigates kidney injury, reduces cortical microcirculatory disorders, and suppresses activation of local inflammation

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Serial Measurement of Cell-cycle Arrest Biomarkers [TIMP-2]•[IGFBP7] and Risk for Progression to Death, Dialysis or Severe Acute Kidney Injury in Patients with Septic Shock

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The current evidence for the treatment of sepsis with Xuebijing injection: Bioactive constituents, findings of clinical studies and potential mechanisms

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Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management

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Anti-sepsis protection of Xuebijing injection is mediated by differential regulation of pro- and anti-inflammatory Th17 and T regulatory cells in a murine model of polymicrobial sepsis

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Lactate as a Potential Biomarker of Sepsis in a Rat Cecal Ligation and Puncture Model

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Micro- and Macrocirculatory Changes During Sepsis and Septic Shock in a Rat Model

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Tissue distribution profiles of multiple major bioactive components in rats after intravenous administration of Xuebijing injection by UHPLC-Q-Orbitrap HRMS

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Rapid determination of 30 bioactive constituents in XueBiJing injection using ultra high performance liquid chromatography-high resolution hybrid quadrupole-orbitrap mass spectrometry coupled with principal component analysis

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Discovery of Xuebijing Injection Exhibiting Protective Efficacy on Sepsis by Inhibiting the Expression of HMGB1 in Septic Rat Model Designed by Cecal Ligation and Puncture

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The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

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Effects of Xuebijing injection on microcirculation in septic shock

(2016) Liang Wang et al.   JOURNAL OF SURGICAL RESEARCH

Xuebijing injection alleviates cytokine-induced inflammatory liver injury in CLP-induced septic rats through induction of suppressor of cytokine signaling 1

(2016) Ailin Li et al.   Experimental and Therapeutic Medicine

Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study

(2015) Eric A. J. Hoste et al.   INTENSIVE CARE MEDICINE

Urinary Biomarkers TIMP-2 and IGFBP7 Early Predict Acute Kidney Injury after Major Surgery

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In situassessment of the renal microcirculation in mechanically ventilated rats using sidestream dark-field imaging

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Remote Ischemic Preconditioning Mitigates Myocardial and Neurological Dysfunction Via KATP Channel Activation in a Rat Model of Hemorrhagic Shock

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A Unified Theory of Sepsis-Induced Acute Kidney Injury

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Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease

(2012) Alice Ding et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury

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The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats

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Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS

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Dose translation from animal to human studies revisited

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