Article
Multidisciplinary Sciences
Nuttinee Salee, Wantida Chaiyana, Artit Yawootti, Srisuwan Naruenartwongsakul, Wannaporn Klangpetch, Ponjan Walter, Niramon Utama-ang
Summary: This study aimed to investigate the use of pulsed electric field assisted water extraction (PEF-AWE) for enhancing the yields of C3G and P3G in black rice grain (BRG) and optimizing the extraction conditions. The results showed that optimized PEF-AWE conditions significantly increased the production of C3G and P3G and modulated the activity of sirtuin1 enzyme.
SCIENTIFIC REPORTS
(2022)
Review
Plant Sciences
Ponnuvel Deepa, Minji Hong, Kandhasamy Sowndhararajan, Songmun Kim
Summary: Obesity is a major health issue worldwide and is associated with various chronic diseases. Cyanidin-3-O-beta-glucoside (C3G), an anthocyanin compound, has shown potential health benefits in reducing obesity-related complications.
Article
Genetics & Heredity
Enerand Mackon, Yafei Ma, Guibeline Charlie Jeazet Dongho Epse Mackon, Babar Usman, Yitong Zhao, Qiufeng Li, Piqing Liu
Summary: This study identified a potential anthocyanin transporter, OsMATE34, in black rice caryopsis and revealed a large number of differentially expressed genes in black and white rice caryopsis at different developmental stages through RNA sequencing analysis.
Review
Biochemistry & Molecular Biology
Enerand Mackon, Guibeline Charlie Jeazet Dongho Epse Mackon, Yafei Ma, Muhammad Haneef Kashif, Niyaz Ali, Babar Usman, Piqing Liu
Summary: Anthocyanins are natural antioxidants that benefit human health. Understanding the complex biosynthesis and storage processes of anthocyanins in rice, which involve multiple genes, is important for rice breeding and genetic engineering. Research on anthocyanins in rice provides valuable insights for the food industry and scientific community.
Article
Food Science & Technology
Sariya Mapoung, Warathit Semmarath, Punnida Arjsri, Pilaiporn Thippraphan, Kamonwan Srisawad, Sonthaya Umsumarng, Kanokkarn Phromnoi, Sansanee Jamjod, Chanakan Prom-U-Thai, Pornngarm Dejkriengkraikul
Summary: This study evaluated the associations between phytochemical contents, antioxidants, and anti-inflammatory properties of different black rice varieties. The results showed that glutinous black rice had higher levels of anthocyanins, antioxidants, and anti-inflammatory properties. Additionally, C3G was strongly associated with antioxidant properties, and P3G was strongly associated with anti-inflammatory properties. Principal component analysis categorized the black rice varieties into three groups based on their characteristics.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Tanisha L. Currie, Marguerite M. Engler, Cara H. Olsen, Victor Krauthamer, Jonathan M. Scott, Patricia A. Deuster, Thomas P. Flagg
Summary: Oxidative stress is a key factor in cognitive decline and atherosclerosis, and berry flavonoids may promote cellular health by exerting antioxidant properties. Black currant and cranberry extracts, as well as their main ingredients D3R and C3G, demonstrate antioxidant effects and can inhibit oxidative stress in microglial and cardiomyocyte cell lines.
Review
Plant Sciences
Liangchuan Guo, Jinli Qiao, Lijun Zhang, Weijiao Yan, Meihui Zhang, Yongchuan Lu, Yutong Wang, Hexi Ma, Yan Liu, Yue Zhang, Jichuan Li, Dong Qin, Junwei Huo
Summary: This review summarizes the recent studies on anthocyanins in blue honeysuckle, including the types of anthocyanins, analysis of their content in berries, extraction and purification methods, as well as the biological effects and recommended utilization of blue honeysuckle.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Food Science & Technology
Umeo Takahama, JiWoo Park, Toshihiro Ansai, Sachiko Hirota
Summary: The study found that high-amylose rice had higher levels of C3G, indicating that C3G binds more efficiently with amylose. The release rate of starch/C3G complexes from cooked rice was highest in high-amylose rice, followed by non-glutinous rice and then glutinous rice. Starch/C3G complexes from high-amylose rice were released slowly, while amylopectin/C3G complexes from glutinous rice were hydrolyzed into smaller complexes that were difficult to further break down.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2022)
Article
Agriculture, Multidisciplinary
Hao Han, Caifen Liu, Wenchuan Gao, Zhongye Li, Gongwei Qin, Shanshan Qi, Hai Jiang, Xinsheng Li, Minghui Liu, Fei Yan, Qingbin Guo, Ching Yuan Hu
Summary: The study found that after the intake of 500 mg/kg cyanidin-3-glucoside in male rats, the primary metabolites were cyanidin and phenolic acids, mainly occurring in the jejunum and ileum between 1 and 5 hours post-ingestion.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Chonlada Bennett, Sujitra Funsueb, Sila Kittiwachana, Phumon Sookwong, Sugunya Mahatheeranont
Summary: This study found that certain mineral elements in the soil can promote the accumulation of anthocyanin content in rice plants and grains. Among the investigated elements, Mg, Se, and Cu treatment resulted in the highest anthocyanin content in the leaves, while B, Cr, and Se had the greatest effect on grain yield. Positive effects on yield components were observed with Mg, Cr, and B. The interaction of Zn*Se and Mg*Cu positively influenced anthocyanin content in grains.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Engineering, Environmental
Dacheng Yang, Yanhong Ran, Xusheng Li, Xinwei Jiang, Jiali Chen, Jianxia Sun, Lingmin Tian, Katia Teerds, Weibin Bai
Summary: The study demonstrated that C3G could mitigate the negative effects of Cd exposure on uterine epithelial cells, potentially preventing Cd-induced female reproductive toxicity. C3G exerts anti-estrogenic effects through various mechanisms to protect the uterus from the harm caused by Cd.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Applied
Xiaohan Wu, Qianwei Lin, Tarun Belwal, Hao Huang, Ligen Zou, Weide Lv, Zisheng Luo
Summary: The study found that the degradation rate of Cyanidin-3-O-glucoside (C3G) was significantly higher under sonophotolysis compared to individual ultrasonics or ultraviolet light photolysis. Additionally, the addition of gallic acid can reduce the degradation of C3G under high-intensity ultraviolet light and ultrasonics, making it more suitable for application in food processing.
Article
Chemistry, Applied
Jianxia Sun, Jiali Chen, Yanmei Bi, Yuhang Xiao, Lijun Ding, Weibin Bai
Summary: This study aimed to improve the stability of Cyanidin-3-glucoside (C3G) through the formation of nanoparticles, and the results indicated that grafting C3G to ss-CD-EP-CMC nanoparticles could significantly enhance its stability.
Article
Food Science & Technology
Itzel Yoali Hernandez-Montesinos, David Fernando Carreon-Delgado, Erik Ocaranza-Sanchez, Carlos Enrique Ochoa-Velasco, Angela Suarez-Jacobo, Carolina Ramirez-Lopez
Summary: This study evaluated the effects of two pretreatments (fermentation with Lactobacillus plantarum and heat processing) and two extraction solvents (70% ethanol and methanol) on the bioactivity of garlic peel extracts. The results showed that the pretreatments significantly increased the total phenolic and flavonoid content of the extracts, as well as their antioxidant and antimicrobial activities against food-spoilage strains. This study reveals an innovative approach to utilize garlic residues as a potential source of antioxidant and antimicrobial agents for food applications.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Meizhi Wan, Sixu Lin, Chang Tan, Mingyue Wang, Yuqi Tong, Yang Zhao, Yanwen Kong, Haotian Deng, Xianjun Meng, Yan Ma
Summary: This study reveals that the complexation of mannoprotein (MP) with cyanidin-3-glucoside (C3G) increases the stability and antioxidant activity of C3G, reduces its susceptibility to external factors, and enhances its bioavailability. The driving forces and structural changes during complexation are identified.
Review
Food Science & Technology
Kehao Huang, Yingzhi Yuan, Xu Baojun
Summary: Microencapsulation is an effective method for incorporating environmentally sensitive bioactive compounds into small capsules to enhance stability and bioavailability. This article provides a systematic review of state-of-the-art microencapsulation methods for bioactive compounds, discussing the differences between two types of microparticles and comparing the physicochemical properties produced by six microencapsulation techniques.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Yifan Zhou, Ammad Ahmad Farooqi, Baojun Xu
Summary: Nutrigenomics has revealed the interaction between diet and genes, deepening our understanding of the role of dietary factors in cancer prevention and inhibition. Dietary saponins have been found to exert anti-cancer activities through the regulation of multiple signaling pathways, but further clinical studies are needed to confirm their effectiveness in humans.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Keyue Wu, Yiyang Li, Yuqi Lin, Baojun Xu, Jiajia Yang, Li Mo, Riming Huang, Xiaoyong Zhang
Summary: This study isolated and characterized a sulfated exopolysaccharide, AVP141-A, from the broth of marine-derived fungus. AVP141-A exhibited potential as an immune activator by significantly enhancing the activity of inflammation factors and activating specific signaling pathways in macrophages. These findings suggest that AVP141-A has the potential for further development as a marine fungal-derived therapeutic compound.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Food Science & Technology
Rizwan Arshad, Saira Masood, Hafiz Rizwan Sharif, Gulden Goksen, Baojun Xu, Muhammad Faisal Manzoor
Summary: Nobiletin (NOB), a natural active ingredient belonging to the citrus family, has potential as an antioxidative, anti-inflammatory, anti-neurodegenerative, and anti-viral agent. Enhancing its solubility and bioavailability is of current interest. Multiple studies cover the therapeutic benefits of NOB against different diseases, but a comprehensive review of its chemistry, metabolism, and curative abilities is lacking.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Xin Huang, Sarita Devi, Matteo Bordiga, Charles S. S. Brennan, Baojun Xu
Summary: Gold nanoparticles (AuNPs) have been widely used in various fields due to their unique physical and chemical properties. Phenolic compounds (PCs), which are the most abundant phytochemicals in foods, have attracted attention for their exceptional health benefits. Recent studies have focused on the synthesis and conjugation of PCs onto AuNPs (AuNP/PC), as well as their bioactivities such as antimicrobial, anticancer, and anti-inflammatory effects. The presence of PCs not only acts as a reductant but also stabilizes the AuNPs during the synthesis process. Evaluating the synthesis parameters and properties of AuNP/PCs is crucial for achieving highly efficient bioactivities. The successful conjugation of PCs with AuNPs is indicated by the presence of surface hydroxyl groups in AuNP/PCs, which greatly enhances their bioactivities.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Jingwen Wang, Zhiling Yu, Ye Peng, Baojun Xu
Summary: Alzheimer's disease (AD) is a progressive neurodegenerative disease with various potential mechanisms involved, and diet intervention has been developed as a strategy for AD prevention. Some bioactive compounds and micronutrients from food have shown neuronal health-promoting effects through antiapoptotic, antioxidative, and anti-inflammatory properties. However, certain dietary components may also trigger AD-related protein production and inflammation. This review provides a comprehensive analysis of the neuroprotective or nerve damage-promoting role and underlying molecular mechanisms of flavonoids, vitamins, and fatty acids, offering insights into the prevention potential of these dietary components against AD.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Yingzi Wu, Jinhai Luo, Baojun Xu
Summary: This study identified the mechanism of geniposide in regulating oxidative stress in colorectal cancer (CRC) through network pharmacology and bioinformatics analysis. The study found that geniposide can regulate oxidative stress and may exert anti-CRC effects through multiple biological processes and signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Biochemistry & Molecular Biology
Baojun Xu
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Nutrition & Dietetics
Bincheng Han, Jinhai Luo, Baojun Xu
Summary: Chroogomphus rutilus is a wild mushroom with important medicinal and economic value, containing various active compounds that have health-promoting effects. Current research is mainly focused on cellular and animal levels, and further clinical trials are needed.
Review
Food Science & Technology
Ashaimaa Y. Moussa, Baojun Xu
Summary: This article reports on the isolated secondary metabolites from 39 edible mushrooms, with 107 compounds showing activity. Among these, 61 compounds demonstrated antitubercular activities, with IC50 values ranging from 0.2 to 50 µg/mL, and 46 compounds showed antimalarial effects, with IC50 values ranging from 0.061 to 36 µg/mL. Despite the identification of over 2,000 strains of edible mushrooms, this review highlights the lack of research on these organisms, which are globally important culinary ingredients. The study conducted a thorough search on basidiomycetes to discuss the chemistry and biology of the isolated compounds, structure-activity relationships, and cytotoxicity profiles, primarily focusing on the active anti-plasmodial and antitubercular molecules. The review emphasizes the significance of lanostane triterpenoids as the only molecules with combined activities against both malaria and tuberculosis, as well as the importance of 3β- and 7α-hydroxylation in the anti-tuberculosis activity and the terminal unsaturated moiety between C-4 and C-28 in the antimalarial activity.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Biochemistry & Molecular Biology
Li Chen, Yuxin Wang, Jiaxin Liu, Zhiyuan Hong, Ka-Hing Wong, Jia-Chi Chiou, Baojun Xu, Carlos L. Cespedes-Acuna, Weibin Bai, Lingmin Tian
Summary: The study aimed to investigate the structural characteristics and in vitro fermentation patterns of polysaccharides from Boletus mushrooms. Polysaccharides were solubilized from selected mushrooms using subcritical water extraction and their physicochemical properties, monosaccharide composition, and molecular weight were analyzed. The utilization of Boletus polysaccharides by gut microbiota and their modulation of microbial communities were studied. The results showed that Boletus polysaccharides exhibited a wide range of molecular weights and were gradually utilized by the human fecal microbiota, promoting the production of SCFAs. The consumption of B. bicolor polysaccharides showed better fermentability and prebiotic effects, making it a potential approach to support gut health.
Review
Biochemistry & Molecular Biology
Ammara Arooj, Roshina Rabail, Muhammad Naeem, Gulden Goksen, Baojun Xu, Rana Muhammad Aadil
Summary: Sesame seeds have therapeutic effects on bone-related health issues due to their rich content of calcium, vitamins, proteins, oil, and carbohydrates. This comprehensive review explores the impact of sesame seeds on bone mineralization in postmenopausal women and highlights their positive influence on bone health, particularly for those with osteoporosis and arthritis. The supplementation of sesame seeds in a regular diet is found to have a protective role and improve hormone balance in women experiencing menopause.
Article
Food Science & Technology
Aien He, Baojun Xu
Summary: This study compared the physiochemical and sensory properties of plant-based milk made from adzuki bean, adlay, and oat, and investigated the effects of household and high-pressure homogenizer on these properties. The results showed that high-pressure homogenization significantly improved the food quality of plant-based milk, and adzuki bean and oat were preferred ingredients.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Kaiyuan Huang, Baojun Xu
Summary: This study focuses on exploring and explaining the bioactive components of Armillaria mellea (AM), as well as its potential applications in cancer treatment and food processing. The research shows that AM contains various compounds with medicinal value, some of which exhibit anticancer activity. In addition, ultrasonic disruption extraction is an effective method in food processing.
Review
Biochemistry & Molecular Biology
Kaiyuan Huang, Baojun Xu
Summary: Research on the nutritional and medicinal properties of wild edible mushrooms, particularly Armillaria mellea (AM), has increased significantly in recent years. Previous studies have identified various biologically active components in AM, including carbohydrates, sterols, fatty acids, sesquiterpenes, and adenosine derivatives. Some specific bioactive substances isolated from AM, like armillarikin, have shown promising anticancer effects. This study aims to provide a comprehensive overview of AM's phytochemical profiles and investigate its therapeutic benefits.
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
