LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non‐alcoholic fatty liver disease

Nur77-activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis

(2020) Yun-feng Guan et al.   ONCOGENE

A novel lncRNA PLK4 up‐regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP‐mediated cell senescence

(2020) Yan Jia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway

(2020) Xingxing Xu et al.   Aging-US

Hepatic Stellate Cell Senescence in Liver Tumorigenesis

(2020) Nadine Martin et al.   HEPATOLOGY

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

(2020) Daniel Q. Huang et al.   Nature Reviews Gastroenterology & Hepatology

Oxidative Stress Induces Telomere Dysfunction and Senescence by Replication Fork Arrest

(2019) Elisa Coluzzi et al.   Cells

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

(2019) Lina Fu et al.   PLOS BIOLOGY

Long non-coding RNA MNX1-AS1 promotes hepatocellular carcinoma proliferation and invasion through targeting miR-218-5p/COMMD8 axis

(2019) Degang Ji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point

(2019) Veverka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999–2019: a systematic review and meta-analysis

(2019) Jie Li et al.   Lancet Gastroenterology & Hepatology

DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response

(2019) Huiming Lu et al.   NUCLEIC ACIDS RESEARCH

A possible relationship between telomere length and markers of neurodegeneration in rat brain after welding fume inhalation exposure

(2019) Mohammad Shoeb et al.   ENVIRONMENTAL RESEARCH

Oroxylin A inhibits ethanol-induced hepatocyte senescence via  YAP pathway

(2018) Huanhuan Jin et al.   CELL PROLIFERATION

dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence

(2018) Giulia Santinon et al.   EMBO JOURNAL

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis

(2018) Xu-Yun Zhao et al.   Nature Communications

A liver-specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis

(2017) Biljana Atanasovska et al.   HEPATOLOGY

Melatonin protects bone marrow mesenchymal stem cells against iron overload-induced aberrant differentiation and senescence

(2017) Fan Yang et al.   JOURNAL OF PINEAL RESEARCH

Lnc-ing ROR1–HER3 and Hippo signalling in metastasis

(2017) Wei Zhuo et al.   NATURE CELL BIOLOGY

ATRX is a regulator of therapy induced senescence in human cells

(2017) Marta Kovatcheva et al.   Nature Communications

Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity

(2017) Ci Ji Lim et al.   Nature Communications

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Sirtuins, Cell Senescence, and Vascular Aging

(2016) Yujiro Kida et al.   CANADIAN JOURNAL OF CARDIOLOGY

Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cells via Suppressing Mitochondrial ROS

(2016) Fan Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Senescence in chronic liver disease: Is the future in aging?

(2016) Aloysious D. Aravinthan et al.   JOURNAL OF HEPATOLOGY

Understanding TERT Promoter Mutations: A Common Path to Immortality

(2016) R. J. A. Bell et al.   MOLECULAR CANCER RESEARCH

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

(2016) H Jin et al.   Cell Death & Disease

Iron absorption in nonalcoholic steatohepatitis and dysmetabolic iron overload syndrome

(2015) Marc Ruivard et al.   HEPATOLOGY

Effects of iron overload on chronic metabolic diseases

(2014) José Manuel Fernández-Real et al.   Lancet Diabetes & Endocrinology

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning

(2013) Mekayla Storer et al.   CELL

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease

(2012) Aloysious Aravinthan et al.   JOURNAL OF HEPATOLOGY

Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease

(2011) Kris V. Kowdley et al.   HEPATOLOGY

p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis

(2010) F Talos et al.   CELL DEATH AND DIFFERENTIATION

Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease

(2010) James E. Nelson et al.   HEPATOLOGY

Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: Enoyl-coenzyme a hydratase down-regulation exacerbates hepatic steatosis

(2009) Xuequn Zhang et al.   HEPATOLOGY

Telomere shortening in the damaged small bile ducts in primary biliary cirrhosis reflects ongoing cellular senescence

(2008) Motoko Sasaki et al.   HEPATOLOGY