The Role of IL-17-Producing Cells in Cutaneous Fungal Infections

The clinical significance of fungi in atopic dermatitis

(2020) Arsa Thammahong et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Paracoccidioides brasiliensis activates mesenchymal stem cells through TLR2, TLR4, and Dectin-1

(2020) Carolina Rodriguez-Echeverri et al.   MEDICAL MYCOLOGY

Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis

(2020) Isaque Medeiros Siqueira et al.   PLoS Neglected Tropical Diseases

Candida and Complement: New Aspects in an Old Battle

(2020) Verena Harpf et al.   Frontiers in Immunology

The role of Th17 cells in psoriasis

(2020) Binbin Li et al.   IMMUNOLOGIC RESEARCH

Fonsecaeapedrosoi Conidia and Hyphae Activate Neutrophils Distinctly: Requirement of TLR-2 and TLR-4 in Neutrophil Effector Functions

(2020) Leandro Carvalho Dantas Breda et al.   Frontiers in Immunology

Candida albicans Virulence Factors and Pathogenicity for Endodontic Infections

(2020) Yeon-Jee Yoo et al.   Microorganisms

Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells

(2020) Dan Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of alpha-mannan by dectin 2 is essential for onset of Kawasaki disease-like murine vasculitis induced by Candida albicans cell-wall polysaccharide

(2019) Toshiaki Oharaseki et al.   Modern Rheumatology

The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation

(2019) Florian Sparber et al.   Cell Host & Microbe

Malassezia ‐derived aryl hydrocarbon receptor ligands enhance the CCL 20/ Th17/soluble CD 163 pathogenic axis in extra‐mammary Paget's disease

(2019) Yota Sato et al.   EXPERIMENTAL DERMATOLOGY

Are new variants of psoriasis therapy ( IL ‐17 inhibitors) safe?

(2019) Dominika Wcisło‐Dziadecka et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Trichophyton tonsurans ‐induced kerion celsi with decreased defensin expression and paradoxically increased interleukin‐17A production

(2019) Yoshihiro Goto et al.   JOURNAL OF DERMATOLOGY

Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2

(2019) L. M. Roesner et al.   Scientific Reports

The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species

(2019) Mohammed Haider et al.   PLoS One

Caspase-11-dependent IL-1α release boosts Th17 immunity against Paracoccidioides brasiliensis

(2019) Natália Ketelut-Carneiro et al.   PLoS Pathogens

Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1

(2019) Jesper B. Moeller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thromboxane A 2 facilitates IL-17A production from Vγ4 + γδ T cells and promotes psoriatic dermatitis in mice

(2018) Yuri Ueharaguchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NLRP3 inflammasome is involved in the recognition of Paracoccidioides brasiliensis by human dendritic cells and in the induction of Th17 cells

(2018) Lívia Furquim de Castro et al.   JOURNAL OF INFECTION

IL-17–Mediated Immunity Controls Skin Infection and T Helper 1 Response during Experimental Microsporum canis  Dermatophytosis

(2018) Verónica L. Burstein et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of interleukin-17 in a murine community-associated methicillin-resistant Staphylococcus aureus pneumonia model

(2018) Yasushi Shibue et al.   MICROBES AND INFECTION

Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression

(2018) Natsuko Saito-Sasaki et al.   Scientific Reports

Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production

(2018) Bilin Dong et al.   PLoS Neglected Tropical Diseases

Sporothrix schenckii Immunization, but Not Infection, Induces Protective Th17 Responses Mediated by Circulating Memory CD4+ T Cells

(2018) Alberto García-Lozano et al.   Frontiers in Microbiology

Resolvin E1 attenuates murine psoriatic dermatitis

(2018) Yu Sawada et al.   Scientific Reports

FIBCD1 Binds Aspergillus fumigatus and Regulates Lung Epithelial Response to Cell Wall Components

(2018) Christine Schoeler Jepsen et al.   Frontiers in Immunology

Candida infections in psoriatic patients on anti-IL17 therapy: a case series

(2018) Manuela Papini et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

The epithelial immune microenvironment (EIME) in atopic dermatitis and psoriasis

(2018) Teruki Dainichi et al.   NATURE IMMUNOLOGY

Cell wall mannan of Candida krusei mediates dendritic cell apoptosis and orchestrates Th17 polarization via TLR-2/MyD88-dependent pathway

(2018) Thu Ngoc Yen Nguyen et al.   Scientific Reports

The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection

(2017) Amanda Costa Gonçalves et al.   IMMUNOLOGY

Staged development of long-lived T-cell receptor αβ T H 17 resident memory T-cell population to Candida albicans after skin infection

(2017) Chang Ook Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Psoriasis pathogenesis and the development of novel targeted immune therapies

(2017) Jason E. Hawkes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TLR9 stimulation induces increase in fungicidal activity of human dendritic cells challenged with Paracoccidioides brasiliensis

(2017) Ivy Rafacho Vieira et al.   MEDICAL MYCOLOGY

Dectin-1 expression by macrophages and related antifungal mechanisms in a murine model of Sporothrix schenckii sensu stricto systemic infection

(2017) Juliana Aparecida Jellmayer et al.   MICROBIAL PATHOGENESIS

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

(2017) Teruaki Nakatsuji et al.   Science Translational Medicine

NOD-Like Receptor P3 Inflammasome Controls Protective Th1/Th17 Immunity against Pulmonary Paracoccidioidomycosis

(2017) Claudia Feriotti et al.   Frontiers in Immunology

The Major Chromoblastomycosis Etiologic Agent Fonsecaea pedrosoi Activates the NLRP3 Inflammasome

(2017) Raffael Júnio Araújo de Castro et al.   Frontiers in Immunology

The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection

(2017) Eliseu Frank de Araújo et al.   Frontiers in Immunology

High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells

(2017) Satoshi Nakamizo et al.   Scientific Reports

A possible pathogenetic role of IL-23/IL-17 axis in rheumatoid nodules in patients with rheumatoid arthritis

(2016) Natsuko Saito-Sasaki et al.   CLINICAL IMMUNOLOGY

Card9- and MyD88-Mediated Gamma Interferon and Nitric Oxide Production Is Essential for Resistance to Subcutaneous Coccidioides posadasii Infection

(2016) Chiung-Yu Hung et al.   INFECTION AND IMMUNITY

Dectin-1 and Dectin-2 promote control of the fungal pathogen Trichophyton rubrum independently of IL-17 and adaptive immunity in experimental deep dermatophytosis

(2016) Fabio SY Yoshikawa et al.   Innate Immunity

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1

(2016) Sofía Sirvent et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic and Invasive Fungal Infections in a Family with CARD9 Deficiency

(2016) Ana Karina Alves de Medeiros et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Tinea Capitis: Current Status

(2016) R. J. Hay   MYCOPATHOLOGIA

Immune response in human chromoblastomycosis and eumycetoma - focusing on human interleukin-17A, interferon-gamma, tumour necrosis factor-alpha, interleukin-1 beta and human beta-defensin-2

(2016) Charussri Leeyaphan et al.   MYCOSES

Skin Immunity to Candida albicans

(2016) Sakeen W. Kashem et al.   TRENDS IN IMMUNOLOGY

Paracoccin Induces M1 Polarization of Macrophages via Interaction with TLR4

(2016) Mateus S. Freitas et al.   Frontiers in Microbiology

Increased circulating Th17 cell in a patient with tinea capitis caused by Microsporum canis

(2016) Yumiko Sakuragi et al.   ALLERGOLOGY INTERNATIONAL

Nociceptive Sensory Fibers Drive Interleukin-23 Production from CD301b+ Dermal Dendritic Cells and Drive Protective Cutaneous Immunity

(2015) Sakeen W. Kashem et al.   IMMUNITY

Optimal clearance of Sporothrix schenckii requires an intact Th17 response in a mouse model of systemic infection

(2015) Lucas Souza Ferreira et al.   IMMUNOBIOLOGY

Dermatomycoses and inflammation: The adaptive balance between growth, damage, and survival

(2015) B. Hube et al.   JOURNAL DE MYCOLOGIE MEDICALE

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis

(2015) Yun Ling et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunological and histopathological characterization of cutaneous candidiasis

(2015) Tacito Graminha Campois et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Role of mannose-binding lectin in intestinal homeostasis and fungal elimination

(2015) L Choteau et al.   Mucosal Immunology

Extracellular vesicles from Paracoccidioides pathogenic species transport polysaccharide and expose ligands for DC-SIGN receptors

(2015) Roberta Peres da Silva et al.   Scientific Reports

IL-1 signaling inhibitsTrichophyton rubrumconidia development and modulates the IL-17 response in vivo

(2015) Fábio Seiti Yamada Yoshikawa et al.   Virulence

The role of pattern recognition receptors in the innate recognition ofCandida albicans

(2015) Nan-Xin Zheng et al.   Virulence

Antigen-Specific Th17 Cells Are Primed by Distinct and Complementary Dendritic Cell Subsets in Oropharyngeal Candidiasis

(2015) Kerstin Trautwein-Weidner et al.   PLoS Pathogens

TLR-4 cooperates with Dectin-1 and mannose receptor to expand Th17 and Tc17 cells induced by Paracoccidioides brasiliensis stimulated dendritic cells

(2015) Flávio V. Loures et al.   Frontiers in Microbiology

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Influence of TLR-2 in the immune response in the infection induced by fungusSporothrix schenckii

(2014) Thais de C. Negrini et al.   IMMUNOLOGICAL INVESTIGATIONS

Chemical Organization of the Cell Wall Polysaccharide Core ofMalassezia restricta

(2014) Thomas Stalhberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skin manifestations of adult T-cell leukemia/lymphoma: Clinical, cytological and immunological features

(2014) Yoshiki Tokura et al.   JOURNAL OF DERMATOLOGY

IL-17A Enhances Vitamin D3-Induced Expression of Cathelicidin Antimicrobial Peptide in Human Keratinocytes

(2014) M. Peric et al.   JOURNAL OF IMMUNOLOGY

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

C-Type Lectin Receptors Differentially Induce Th17 Cells and Vaccine Immunity to the Endemic Mycosis of North America

(2014) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Dectin-1 Induces M1 Macrophages and Prominent Expansion of CD8+IL-17+ Cells in Pulmonary Paracoccidioidomycosis

(2014) Flávio V. Loures et al.   JOURNAL OF INFECTIOUS DISEASES

IL-23 from Langerhans Cells Is Required for the Development of Imiquimod-Induced Psoriasis-Like Dermatitis by Induction of IL-17A-Producing γδ T Cells

(2014) Ryutaro Yoshiki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Global epidemiology of sporotrichosis

(2014) A. Chakrabarti et al.   MEDICAL MYCOLOGY

A Chitin-Like Component on Sclerotic Cells of Fonsecaea pedrosoi Inhibits Dectin-1-Mediated Murine Th17 Development by Masking β-Glucans

(2014) Bilin Dong et al.   PLoS One

In Situ Immune Response in Human Chromoblastomycosis – A Possible Role for Regulatory and Th17 T Cells

(2014) Aline Alves de Lima Silva et al.   PLoS Neglected Tropical Diseases

Defective epidermal induction of S100A7/psoriasin associated with low frequencies of skin-infiltrating Th17 cells in dermatophytosis-prone adult T cell leukemia/lymphoma

(2013) Yu Sawada et al.   CLINICAL IMMUNOLOGY

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

Deep Dermatophytosis and Inherited CARD9 Deficiency

(2013) Fanny Lanternier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-like receptors (TLR2 and TLR4) recognize polysaccharides of Pseudallescheria boydii cell wall

(2012) Rodrigo Tinoco Figueiredo et al.   CARBOHYDRATE RESEARCH

The role of galectin-3 in phagocytosis ofCandida albicansandCandida parapsilosisby human neutrophils

(2012) Jennifer R. Linden et al.   CELLULAR MICROBIOLOGY

Defective Epidermal Innate Immunity and Resultant Superficial Dermatophytosis in Adult T-cell Leukemia/Lymphoma

(2012) Y. Sawada et al.   CLINICAL CANCER RESEARCH

Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis

(2012) Carmelo Biondo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory response of human keratinocytes triggered by Sporothrix schenckii via toll-like receptor 2 and 4

(2012) Min Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Langerhans Cells Require MyD88-Dependent Signals for Candida albicans Response but Not for Contact Hypersensitivity or Migration

(2012) K. Haley et al.   JOURNAL OF IMMUNOLOGY

Update of Immune Events in the Murine Contact Hypersensitivity Model: Toward the Understanding of Allergic Contact Dermatitis

(2012) Tetsuya Honda et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD8+ T Cells in the Lesional Skin of Atopic Dermatitis and Psoriasis Patients Are an Important Source of IFN-γ, IL-13, IL-17, and IL-22

(2012) DirkJan Hijnen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Taenia taeniaeformis in Rat Favors Protracted Skin Lesions Caused by Sporothrix schenckii Infection: Dectin-1 and IL-17 Are Dispensable for Clearance of This Fungus

(2012) Xiaohui Zhang et al.   PLoS One

Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

(2011) Maria da Glória Sousa et al.   Cell Host & Microbe

MyD88 Signaling Is Required for Efficient Innate and Adaptive Immune Responses to Paracoccidioides brasiliensis Infection

(2011) Flávio V. Loures et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9 Modulates Macrophage Antifungal Effector Function during Innate Recognition of Candida albicans and Saccharomyces cerevisiae

(2011) Pia V. Kasperkovitz et al.   INFECTION AND IMMUNITY

Vaccine Immunity to Coccidioidomycosis Occurs by Early Activation of Three Signal Pathways of T Helper Cell Response (Th1, Th2, and Th17)

(2011) Chiung-Yu Hung et al.   INFECTION AND IMMUNITY

Malassezia sympodialis thioredoxin–specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis

(2011) Hari Balaji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

(2011) Marcel Wüthrich et al.   JOURNAL OF CLINICAL INVESTIGATION

Skin as a Peripheral Lymphoid Organ: Revisiting the Concept of Skin-Associated Lymphoid Tissues

(2011) Gyohei Egawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Paracoccidioidomycosis: Cells expressing IL17 and Foxp3 in cutaneous and mucosal lesions

(2011) Carla Pagliari et al.   MICROBIAL PATHOGENESIS

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease

(2010) Stewart Leung et al.   Cellular & Molecular Immunology

TLR4 RecognizesPseudallescheria boydiiConidia and Purified Rhamnomannans

(2010) Rodrigo T. Figueiredo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Susceptibility of TLR4-defective C3H/HeJ mice toCoccidioides posadasiiinfection

(2010) Shanjana Awasthi   MEDICAL MYCOLOGY

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

Response of macrophage Toll-like receptor 4 to aSporothrix schenckiilipid extract during experimental sporotrichosis

(2009) Micheli F. Sassá et al.   IMMUNOLOGY

Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

(2009) A. Miyazato et al.   INFECTION AND IMMUNITY

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

(2009) Terry K. Means et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines

(2009) Consuelo Ortega et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lack of Galectin-3 Drives Response to Paracoccidioides brasiliensis toward a Th2-Biased Immunity

(2009) Luciana Pereira Ruas et al.   PLoS One

Vitamin D Analogs Differentially Control Antimicrobial Peptide/“Alarmin”Expression in Psoriasis

(2009) Mark Peric et al.   PLoS One

IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response

(2008) Kilian Eyerich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis

(2008) Chizuko Koga et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY