Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells

Cyclin-Dependent Kinase 5 (CDK5)-Mediated Phosphorylation of Upstream Stimulatory Factor 2 (USF2) Contributes to Carcinogenesis

(2019) Tabughang Chi et al.   Cancers

Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study

(2019) Sophie Glatt et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis

(2018) Keiji Hirota et al.   IMMUNITY

IL-33/IL-31 Axis: A Potential Inflammatory Pathway

(2018) Eleonora Di Salvo et al.   MEDIATORS OF INFLAMMATION

PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells

(2018) Muluken S. Belew et al.   Stem Cell Reports

USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis

(2018) Yawen Tan et al.   CELLULAR SIGNALLING

Curcumin inhibiting Th17 cell differentiation by regulating the metabotropic glutamate receptor-4 expression on dendritic cells

(2017) Guangming Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Selected cytokine pathways in rheumatoid arthritis

(2017) Mélissa Noack et al.   Seminars in Immunopathology

Selective dysfunction of subsets of peripheral blood mononuclear cells during pediatric dengue and its relationship with clinical outcome

(2017) Federico Perdomo-Celis et al.   VIROLOGY

Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis

(2017) Dan Hu et al.   Nature Communications

IL-23 and Th17 Disease in Inflammatory Arthritis

(2017) et al.   Journal of Clinical Medicine

The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis

(2017) Shigeru Kotake et al.   Journal of Clinical Medicine

Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation

(2017) Jürgen Brück et al.   Scientific Reports

Therapeutic Targeting of IL-17 and IL-23 Cytokines in Immune-Mediated Diseases

(2016) George E. Fragoulis et al.   Annual Review of Medicine

Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats

(2016) Mingming Zhang et al.   BMC GASTROENTEROLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Infliximab Reduces the Frequency of Interleukin 17-Producing Cells and the Amounts of Interleukin 17 in Patients With Rheumatoid Arthritis

(2016) Hui Shen et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Treatment of low doses curcumin could modulate Th17/Treg balance specifically on CD4+ T cell cultures of systemic lupus erythematosus patients

(2015) Kusworini Handono et al.   Central European Journal of Immunology

The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis

(2015) Sandra M.J. Paulissen et al.   CYTOKINE

Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions

(2015) Dhavalkumar D. Patel et al.   IMMUNITY

Altered Immunoregulation in Rheumatoid Arthritis: The Role of Regulatory T Cells and Proinflammatory Th17 Cells and Therapeutic Implications

(2015) Alessia Alunno et al.   MEDIATORS OF INFLAMMATION

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(2015) Karin Andersson et al.   MOLECULAR MEDICINE

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

Protein kinases as switches for the function of upstream stimulatory factors: implications for tissue injury and cancer

(2015) Tina Horbach et al.   Frontiers in Pharmacology

TNFαPromotes Th17 Cell Differentiation through IL-6 and IL-1βProduced by Monocytes in Rheumatoid Arthritis

(2014) Yingxia Zheng et al.   Journal of Immunology Research

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

IL-17 and TNF Synergistically Modulate Cytokine Expression while Suppressing Melanogenesis: Potential Relevance to Psoriasis

(2013) Claire Q.F. Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Human Th17 subsets

(2012) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Secukinumab failure in Crohn's disease: the yeast connection?

(2012) Jean Frédéric Colombel et al.   GUT

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

Upstream Stimulating Factors Regulate the Expression of ROR T in Human Lymphocytes

(2012) M. Ratajewski et al.   JOURNAL OF IMMUNOLOGY

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

(2011) Lorenzo Cosmi et al.   ARTHRITIS AND RHEUMATISM

CCR6 as a mediator of immunity in the lung and gut

(2011) Toshihiro Ito et al.   EXPERIMENTAL CELL RESEARCH

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

Resolving the identity myth: Key markers of functional CD4+FoxP3+ regulatory T cells

(2011) Xin Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells

(2010) Mostafa A. Gabr et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

(2009) H. G. Evans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review

(2009) Andrea Rubbert-Roth et al.   ARTHRITIS RESEARCH & THERAPY