Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2

The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV

(2019) João T. Monteiro et al.   Viruses-Basel

RNA-Seq Profile Reveals Th-1 and Th-17-Type of Immune Responses in Mice Infected Systemically with Aspergillus fumigatus

(2018) Jata Shankar et al.   MYCOPATHOLOGIA

C-Type Lectin Receptor (CLR)–Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates

(2018) Sabine Mayer et al.   Frontiers in Immunology

β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant T H 2/T H 17 responses

(2017) Zhonghua Zhang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-1 plays a critical role in HDM-induced PGE 2 production in macrophages

(2017) Takashi Ito et al.   ALLERGOLOGY INTERNATIONAL

C-type lectins: their network and roles in pathogen recognition and immunity

(2016) Sabine Mayer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

IL-1β enhances inflammatory T H 2 differentiation

(2016) Stephan M. Caucheteux et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

(2016) Thomas Werfel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-1 Plays an Important Role in House Dust Mite–Induced Allergic Airway Inflammation through the Activation of CD11b+Dendritic Cells

(2016) Takashi Ito et al.   JOURNAL OF IMMUNOLOGY

Malassezia spp.-specific Immunoglobulin E Level is a Marker for Severity of Atopic Dermatitis in Adults

(2015) M Glatz et al.   ACTA DERMATO-VENEREOLOGICA

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14

(2015) J. J. Fong et al.   EMBO JOURNAL

Differential cytokine induction by the human skin–associated autoallergen thioredoxin in sensitized patients with atopic dermatitis and healthy control subjects

(2015) Susanne Hradetzky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Der p1 and Der p2-Specific T Cells Display a Th2, Th17, and Th2/Th17 Phenotype in Atopic Dermatitis

(2015) Lennart M. Roesner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dectin-2 promotes house dust mite-induced Th2 and Th17 cell differentiation and allergic airway inflammation in mice

(2014) Ayako Norimoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Malasseziayeasts activate the NLRP3 inflammasome in antigen-presenting cells via Syk-kinase signalling

(2014) Magdalena Kistowska et al.   EXPERIMENTAL DERMATOLOGY

IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage

(2014) G. L. Stritesky et al.   JOURNAL OF IMMUNOLOGY

Dectin-2 Regulates the Effector Phase of House Dust Mite-Elicited Pulmonary Inflammation Independently from Its Role in Sensitization

(2014) M. W. Parsons et al.   JOURNAL OF IMMUNOLOGY

Identification of Distinct Ligands for the C-type Lectin Receptors Mincle and Dectin-2 in the Pathogenic Fungus Malassezia

(2013) Tetsuaki Ishikawa et al.   Cell Host & Microbe

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation

(2013) Maha Maglinao et al.   JOURNAL OF CONTROLLED RELEASE

Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation

(2013) D L Clarke et al.   Mucosal Immunology

Signaling through Toll-like receptor 3 and Dectin-1 potentiates the capability of human monocyte-derived dendritic cells to promote T-helper 1 and T-helper 17 immune responses

(2012) Ana Dragicevic et al.   CYTOTHERAPY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

Triggering of specific Toll-like receptors and proinflammatory cytokines breaks allergen-specific T-cell tolerance in human tonsils and peripheral blood

(2012) Umut Can Kücüksezer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses

(2011) Kavita Reginald et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

(2011) Nora A. Barrett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Heat-shock proteins can promote as well as regulate autoimmunity

(2009) Rajesh Rajaiah et al.   AUTOIMMUNITY REVIEWS

Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes

(2009) M. Kobayashi et al.   BRITISH JOURNAL OF DERMATOLOGY

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response

(2008) Kilian Eyerich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of Malassezia in atopic dermatitis affecting the head and neck of adults

(2008) Kamruz Darabi et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY