Colorectal Cancer Apoptosis Induced by Dietary δ-Valerobetaine Involves PINK1/Parkin Dependent-Mitophagy and SIRT3

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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BAG6 promotes PINK1 signaling pathway and is essential for mitophagy

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Colorectal Cancer and Diet

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Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production

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Cyclovirobuxine D Induced-Mitophagy through the p65/BNIP3/LC3 Axis Potentiates Its Apoptosis-Inducing Effects in Lung Cancer Cells

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Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress

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BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy

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ROS-Mediated Apoptotic Cell Death of Human Colon Cancer LoVo Cells by Milk δ-Valerobetaine

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Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell

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Synergistic Effect of Dietary Betaines on SIRT1-Mediated Apoptosis in Human Oral Squamous Cell Carcinoma Cal 27

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L-Carnitine Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme

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Antioxidant and Anti-Inflammatory Activities of Buffalo Milk δ-Valerobetaine

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Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity

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Mitophagy in Cancer: A Tale of Adaptation

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Sirtuin 3 silencing impairs mitochondrial biogenesis and metabolism in colon cancer cells

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PINK1 import regulation at a crossroad of mitochondrial fate: the molecular mechanisms of PINK1 import

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Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1α mediated signal pathway

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Ruminant meat and milk contain δ-valerobetaine, another precursor of trimethylamine N-oxide (TMAO) like γ-butyrobetaine

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Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer

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The multifaceted contributions of mitochondria to cellular metabolism

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Emodin Induces Apoptosis of Colon Cancer Cells via Induction of Autophagy in a ROS-Dependent Manner

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Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway

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Role of mitochondrial function in the invasiveness of human colon cancer cells

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SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production

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PINK1/Parkin-mediated mitophagy in mammalian cells

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Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy

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Elimination of damaged mitochondria through mitophagy reduces mitochondrial oxidative stress and increases tolerance to trichothecenes

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Parkin Sensitizes toward Apoptosis Induced by Mitochondrial Depolarization through Promoting Degradation of Mcl-1

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The Sirtuin 3 Expression Profile Is Associated with Pathological and Clinical Outcomes in Colon Cancer Patients

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The Synergistic Effect of Everolimus and Chloroquine on Endothelial Cell Number Reduction Is Paralleled by Increased Apoptosis and Reduced Autophagy Occurrence

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Parkin Pathway Activation Mitigates Glioma Cell Proliferation and Predicts Patient Survival

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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

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PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice

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