A novel platform for drug testing: Biomimetic three-dimensional hyaluronic acid-based scaffold seeded with human hepatocarcinoma cells

Understanding MAPK Signaling Pathways in Apoptosis

(2020) Jicheng Yue et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor-Stroma Interactions Alter the Sensitivity of Drug in Breast Cancer

(2020) Virginia Brancato et al.   Frontiers in Materials

The impact of photocatalytic Ag/TiO2 and Ag/N-TiO2 nanoparticles on human keratinocytes and epithelial lung cells

(2019) Daniela Rebleanu et al.   TOXICOLOGY

The comet assay applied to HepG2 liver spheroids

(2019) Elisabeth Elje et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Targeting STAT3 inhibition to reverse cisplatin resistance

(2019) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis

(2019) Monica Madalina Tucureanu et al.   Diabetes & Vascular Disease Research

Comparison of 2D and 3D cell culture models for cell growth, gene expression and drug resistance

(2019) Julia C. Fontoura et al.   Materials Science & Engineering C-Materials for Biological Applications

Galangin (GG) combined with cisplatin (DDP) to suppress human lung cancer by inhibition of STAT3-regulated NF-κB and Bcl-2/Bax signaling pathways

(2018) Shuo Yu et al.   BIOMEDICINE & PHARMACOTHERAPY

Zingiber officinale extract administration diminishes steroyl-CoA desaturase gene expression and activity in hyperlipidemic hamster liver by reducing the oxidative and endoplasmic reticulum stress

(2018) Mihaela Georgiana Carnuta et al.   PHYTOMEDICINE

Generation and characterization of hepatocellular carcinoma cell lines with enhanced cancer stem cell potential

(2018) Julienne K. Muenzner et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phytochemicals: Current strategy to sensitize cancer cells to cisplatin

(2018) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

A versatile 3D tissue matrix scaffold system for tumor modeling and drug screening

(2017) Girdhari Rijal et al.   Science Advances

Comparative analysis of 3D culture methods on human HepG2 cells

(2016) Claudia Luckert et al.   ARCHIVES OF TOXICOLOGY

3D scaffolds in breast cancer research

(2016) Girdhari Rijal et al.   BIOMATERIALS

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

(2016) Dario Barbone et al.   PLoS One

Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis

(2016) Hany A. Omar et al.   PLoS One

Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors

(2015) Man Yu et al.   CANCER SCIENCE

Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a

(2015) LIRUI ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preparation and physical properties of hyaluronic acid-based cryogels

(2015) Anna Ström et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Hepatocellular Carcinoma

(2015) M.-A. Buendia et al.   Cold Spring Harbor Perspectives in Medicine

Evaluation of Three-Dimensional Cultured HepG2 Cells in a Nano Culture Plate System: an In Vitro Human Model of Acetaminophen Hepatotoxicity

(2014) Kohei Aritomi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A silk fibroin based hepatocarcinoma model and the assessment of the drug response in hyaluronan-binding protein 1 overexpressed HepG2 cells

(2013) Banani Kundu et al.   BIOMATERIALS

Use of Molecular Biomarkers to Quantify the Spatial Distribution of Effects of Anticancer Drugs in Solid Tumors

(2013) J. K. Saggar et al.   MOLECULAR CANCER THERAPEUTICS

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function

(2012) Aleksander Skardal et al.   BIOMATERIALS

Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma

(2011) M Yamasaki et al.   BRITISH JOURNAL OF CANCER

The cytoskeletal organization of breast carcinoma and fibroblast cells inside three dimensional (3-D) isotropic silicon microstructures

(2010) Mehdi Nikkhah et al.   BIOMATERIALS

Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration

(2010) Jennifer Patterson et al.   BIOMATERIALS

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Anticancer drug development: the grand challenges

(2010) William N. Hait   NATURE REVIEWS DRUG DISCOVERY

Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening

(2010) Sebastian Greenhough et al.   TOXICOLOGY

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

(2007) Laurent David et al.   Acta Biomaterialia

Control of the molecular degradation of hyaluronic acid hydrogels for tissue augmentation

(2007) Eun Ju Oh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A